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100
Exam 2
57
Physics
Professional
11/08/2011

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Term
Define "velocity"
Definition
speed (distance over time)
Term
What are the SI units for velocity?
Definition
m/sec
Term
What are the CGS units for velocity?
Definition
cm/sec
Term
What are the British units for velocity?
Definition
ft/sec
Term
Which units of velocity are used for echocardiograhy?
Definition
SI: m/sec
Term
Which units of velocity are used for vascular?
Definition
CGS: cm/sec
Term
What is the equation that defines the relationship among flow, velocity, and area?
Definition
Q=A•V
Term
If the area of the aorta is 3.3 cm², what is the diameter? (How do you obtain the diameter?)
Definition
D = 2√(A/π)
D = 2√(3.3/π)
= 2.05 cm
Term
If the diameter of the aorta is 2.05 cm, what is the area? (How do you obtain the area?)
Definition
A = D²•0.785
A = 2.05²•0.785
3.3 cm²
Term
If the velocity is 33 cm/sec, and the flow is 4.4 L/min, what is the diameter of the aorta? (How do you obtain the diameter?)
Definition
A=Q/V
First, convert Q to cm³/sec
4.4 L/min(1000/60) = 73.33 cm³/sec
A=73.33/33
A=2.22 cm²
Term
If the area of the aorta is 2.7 cm², and the flow is 5.1 L/min, and the aorta branches in arteries totaling 50 cm², what is the velocity in each branch artery? (How do you obtain the velocity?)
Definition
V=Q/Total CSA of branches
First, convert Q to cm³/sec
5.1 L/min(1000/60) = 85 cm³/sec
V=85/50 = 1.7 cm/sec

*The area of the aorta is insignificant information
Term
What is the first branch off the aorta not including the coronary arteries.
Definition
Brachiocephalic (Innominate) Artery
Term
The velocity of blood flow in the LVOT is 88 cm/sec, and the area of the LVOT is 7.7 cm², and the velocity in the aortic valve is 4.4 m/sec. What is the valve area? (How do you obtain the area?)
Definition

V1A1=V2A2

in this case:

(V1A1)/V2

But first convert V2 to cm/sec:

4.4 m/sec • 100 = 440 cm/sec

A2 = (88•7.7)/440 = 1.54 cm2

 

Term
Define "laminar" blood flow
Definition
Blood flowing in orderly, undisturbed, concentric layers.
Term
What are the two basic velocity profiles? Where and when do they occur?
Definition
Plug and parabolic.
Plug profile occurs during acceleration in systole in larger vessles and at stenoses and branches.
Parabolic profile occurs during diastole in larger vessels and throughout the smaller vessles all the time.
Term
Describe parabolic flow profile
Definition
Velocity is highest in the center, dropping off toward wall. Peak velocity is twice the mean velocity. Velocity at walls is theoretically zero.
Term
Describe plug flow profile
Definition
Velocities are the same almost all the way across the lumen. Wall drag still slows down the outer layers.
Term
Define "turbulence" and what noises might it cause in the body?
Definition
Chaotic and disorderly flow. In cardiac studies, turbulence is called a "murmur" and called a "brooie" in vascular studies.
Term
What are the variables that influence the likelihood of turbulence?
Definition
If V=velocity, d=diameter or ρ=density is increased, or η=viscosity is decreased, the likelihood of turbulence will increase.
Term
Give the equation that predicts the likelihood of turbulence and who developed it?
Definition
The Reynolds number equation:
Re=Vρd/η

V=velocity, d=diameter, ρ=density, η=viscosity

A Reynolds number >2000 predicts turbulence
Term
What is the effect on the likelihood of turbulence with a tripling of viscosity?
Definition
The likelihood of turbulence will decrease 1/3.
Term
When might a cardiac murmur be normal?
Definition
During systole
Term
When is a cardiac murmur never normal?
Definition
During diastole
Term
Define "viscosity"
Definition
An internal friction created by molecular attraction, creating a tendency to resist motion.
Term
What degree of stenosis must be reached in most arteries to be critical?
Definition
70% or greater
Term
How is "critial stenosis" defined?
Definition
A sudden reduction in flow and blood pressure.
Term
What is the the behavior of blood flow before, within, and distal to the hemodynamically significant stenosis?
Definition
There is no noticable change in blood flow, but within the stenosis, the velocity increase due to the narrowing of the vessel. Once the flow is distal to the stenosis, turbulence ensues.
Term
What happens to pressure within a stenosis and why?
Definition
There is a reduction in pressure due to the Bernoulli effect which states, "As the speed of a moving fluid increases, the pressure within the fluid decreases."
Term
If velocity through a mitral valve is 410 cm/sec, what is the pressure gradient across the valve?
Definition

P1-P2 = 4(V2)

First, convert cm to m

410 cm/sec • 100 = 4.1 m/sec

ΔP = 4(4.12) = 67 mmHg

Term
What is the most common complication resulting from atherosclerotic diease in the coronary arteries?
Definition
Myocardial Infarction
Term
What is the most common complication resulting from atherosclerotic diease in the carotid arteries?
Definition
Ischemic Stroke
Term
What is almost always the first symptom of lower extremity PAD?
Definition
Pain with exercise, relief with rest.
Term
What is an aneurysm and possible causes?
Definition
Weakening and bulging of the cardiac or arterial wall. Can be due to infarcted tissue, atherosclerotic degeneration, infection, or congenital weakness.
Term
What is the formula for the Law of LaPlace? Define the variables. Explain its significance in the vascular system.
Definition
T∝P•d
Wall tention (T) is proportional to (∝) pressure (P) multiplied by diameter(d). The larger the vessel's diameter, the more tension is required to sustain a given pressure. In the body, the mean pressure doesn't change much--it's the diameter that changes as the wall weakens, requiring more wall tension to hold things together.
Term
What are the units for wall tention?
Definition
dynes/cm
Term
What happens to wall tension if the diameter is tripled?
Definition
T∝P•d
It increases
Term
What is usually found on the wall of an aneurysm?
Definition
A thrombus
Term
What are the two basic functions of the venous part of the circulatory system?
Definition
To return blood back to the heart and venous resevior.
Term
What are the two possible useful functions of the venous reservor?
Definition
To provide increased flow during exercise and provide volume to the core circulation in the event of severe hemorrhage.
Term
What is compliance?
Definition
The ability to expand and contgain more volume with little pressure increase.
Term
What makes veins compliant?
Definition
Veins are compliant because of normally semi-collapsed state.
Term
What makes arteries compliant?
Definition
Elastin
Term
What are the physical characteristics of veins compared to arteries.
Definition
Roughly half the wall thickness than arteries. Veins contain less elastin and smooth muscle in the media comparted to arteries.
Term
Define "hydrostatic pressure"
Definition
Force of gravity acting on a column of fluid.
Term
How much hydrostatic pressure is possible in an average person standing still for a long time?
Definition
90 mmHg
Term
What structures help prevent hydrostatic pressure from happening?
Definition
Venous valves and calf muscle.
Term
What are the 5 mechanisms that help with venous return to the heart?
Definition
1. Venous valves
2. Skeletal muscle pump
3. Respiratory pump
4. Cardiac suction effect
5. Vasomotor tone
Term
What are the 3 types of venous structures in the lower extremities, and how do they function?
Definition
Flow moves from (1) superficial veins to (2) deep veins via (3) perforating veins.
Term
What is Virchow's triad?
Definition
1. Stasis
2. Hypercoagulability
3. Vessel wall injury
Term
How is LE DVT thought to form?
Definition
DVT is thought to originate often in two places from stasis:
1. Muscular veins in calf
2. Behind valve leaflets
Term
What is the most serious complication of DVT?
Definition
Pulmonary Embolism
Term
What are the two basic types of testing for DVT?
Definition
1. Venous outflow plethysmography
2. Ultrasound
Term
How is venous imaging performed?
Definition
Ultrasound
Term
What demostrates patency of the vein?
Definition
Compress veins with ultrasound probe to provoke reflux.
Term
What image characteristics are present for acute thrombus?
Definition
1. Dark intraluminal echoes
2. Homogeneous echoes
3. Distension of vein
4. Poor wall attachment ("tail")
Term
What image characteristics are present for chronic thrombus?
Definition
1. Bright intraluminal echoes
2. Heterogeneous echoes
3. Possible retracted, small lumen
4. Well attached to wall
5. May see recanalization collaterals
6. Vein may be invisible
Term
How is Doppler ultrasoundused to diagnose venous valvular insuffciency?
Definition
flow direction, proximal compression, distal release.
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