Term
| How much specimen do you send to the lab? |
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Definition
| as much as you can, ecept if its tissue then you need one gram |
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Term
| At what temperature do you culture? |
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Definition
|
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Term
| How much blood do you need for a blood culture? |
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Definition
|
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Term
| How long does it take to get a blood culture back? |
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Definition
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Term
| Antiobiotic selection is based on ____ decisions. |
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Definition
| P and T formulary decisions |
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Term
| What are the three different classifications of zone sizes that determine the susceptibility of antibiotics when testing disk diffusion? |
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Definition
| sesitive, intermediate, resistant |
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Term
| What are the different ways to measure antibiotic susceptibility to an unknown organism you are culturing? |
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Definition
| kirby bauer susceptibilities, minimum inhibitory concentration, automated systems |
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Term
| How do automated systems tell you info about organism susceptibility? |
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Definition
| panels of drugs are based on organism and classes of drug; approximation of real MIC (minimum inhibitory concentration) |
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Term
| What type of test can you use for fastidious/difficult organisms? |
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Definition
|
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Term
|
Definition
| minimal inhibition concentration that inhibits 90% of isolates |
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Term
| How do antibiograms help? |
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Definition
| empiric therapy selection (prior to organism ID and after organism ID), tracking hospital trends, formulatory decisions, information to regional/national agencies |
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Term
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Definition
| ones that ahve an inducible beta-lactamase (serratia, peudomonas, indole-+ proteus, citrobacter, enterobacter) |
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Term
| What is pharmocokinetics? |
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Definition
| determining how dosage regimen determines concentration versus time in serum and where else besides the serum the drug is concentrated at |
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Term
| What is pharymacodynamics? |
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Definition
| concentration versus time in tissues and other body fluids & concentration versus time at the site of infection. And how these things lead to pharmacologic or toxicologic effects and how they effect the microbe. |
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Term
|
Definition
| the area under the drug concentration over time curve that is above the MIC |
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