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1.11 CBC
By Dr. Jely
23
Pathology
Professional
01/12/2012

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Cards

Term
What are the units of RBC count?
Definition
number/uL
Term
What is hematocrit?
Definition
percent volume of pack erythrocytes to whole blood sample
Term
How is hct calculated?
Definition
HCT = (MCV X RBC)/10
Term
What is a estimated mathematical relationship between RBC, HGB, and HCT?
Definition
RRBC x 3= HGB
HGB x 3 = HCT
Term
What is MCH?
Definition
relationship between individual red blood cells and the hemoglobin concentration
Term
What is MCHC?
Definition
red blood cell population as a whole and the hemoglobin concentration
Term
Units of MCV=
Definition
u3 or femtoliters (fL)
Term
What cause macrocytic anemias?
Definition
megaloblastic anemia, polychromasia, or reticuocytosis
Term
MCV is decreased in what type of anemia?
Definition
microcytic hypochromic anemia
Term
How do you calculate MCH?
Definition
MCH=(HGB/RBC) x 10
Term
How do you calculate MCHC?
Definition
HGB/HCT
Term
An increase in MCHC is seen only in what two disorders?
Definition
spherocytosis and cold agglutinin
Term
What is the first value to become abnormal in blood loss?
Definition
RDW
Term
RDW can be used to diagnose what genetic RBC disorder?
Definition
thalassemia syndromes
Term
What do you call a population of red blood cells that vary from each other in size and shape?
Definition
anisopoikilocytosis
Term
Why are platelets difficult to count?
Definition
they are small, must be differentiated from debris, have a tendency to adhere to glass/foreign body or each other causing a false low count to be obtained
Term
What are the two types of causes of thrombocytosis?
Definition
reactive (e.g. d/t blood loss) or primary (e.g. myeloproliferative neoplasm such as essential thrombocythemia)
Term
What can cause decreased production of platlets?
Definition
decreased number of megakaryocytes d/t marrow replacement by a metastatic tumor or leukemia or ineffective production as in megaloblastic anemia
Term
What can cause increased destruction of platelets leading to thrombocytopenia?
Definition
immune thrombocytopenia or disseminated intravascular coagulation
Term
What lab value varies inversely with the platelet count?
Definition
the average volume or size of the platelets
Term
What is the corrected WBC?
Definition
WBC minus the NRBCs
Term
What age group has NRBCs?
Definition
newborns
Term
Does the manual cell count provide the relative or absolute differential WBC count?
Definition
relative
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