Hidradenitis Suppurativa
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Only after puberty
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Sinus tracts
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1) Women 2) AA 3) h/o acne 4) Tight, curly hair (ingrown) 5) Obesity 6) Tight clothing
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1) I&D 2) PO or topical abx 3) Bleach baths 4) Laser 5) Accutane
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Bullous Pemphigoid
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IgG autoantibodies bind to the basement membrane leading to separation of dermis from epidermis
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Unknown
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Rare. Onset usu. >65yo, men = women
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Tense bullae that heal /s scarring
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Fleural surfaces
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1) Topical steroids 2) Long-term oral prednisone 3) Tertacycline 4) Methotextrate 5) Immunosuppressants
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Vitiligo
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20yo
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Sharply circumscribed white patches that become confluent. MC face, neck, scalp.
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Unknown. Autoimmune, some genetic inheritance.
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1) Topical steroids 2) Topical immunomodulators (protopic, Elidel) 3) UV 4) Laser 5) Oral steroids 6) Depigmentation 7) Surgery
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Dermatitis herpetiformis
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30's
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Very pruritic, burning sensation, erythematous excoriated papules or plaques and herpetiform lesions
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Elbows, knees, and buttock. Palms and soles are spared.
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Biopsy
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1) Gluten free diet 2) Dapsone
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Hemolysis, methemoglobinemia, peripheral neuropathy, cross rxn w/ sulfa allergy
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lymphoma and intestinal CA
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Psoriasis
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Autoimmune. Fast turnover of dermal cells - 3 to 5 days (normal 23days)
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Elbows and knees. Plaque psoriasis.
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1) Plaque 2) Guttate 3) Inverse 4) Pustular 5) Erythrodermic
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<1cm "dew drop" plaques all over the body.
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Young, healthy people. Typicalll /p strep infection.
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Moist, "beefy red", not scaly. Occurs in skin folds, axillae, groin.
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palms and soles
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Generalized erythema and scale.
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No
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Koebner phenomenon
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NSAIDS, Lithium, Inderal, Indomethacin, anti-malarials, beta blockers
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psoriatic arthritis
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Topical and intranasal steroids
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1) UV 2) Biologics (Enbrel, Humira, Amevive, Remicade, Raptiva) 3) Methotextrate 4) Cyclosporin
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Vitamin D analogue (Dovonex, Vectical)
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Pityriasis Rosea
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15-40yo. Trunk.
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Collarette of fine scale OR Christmas tree pattern that is symmetric and gen. on trunks and extremities
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Viral. Spring and Fall.
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None - self limiting 8-12wks. UV can help, mild topical steroids PRN.
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Asthma and allergies
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The itch that rashes
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Red papules or plaques with scale, lichenification
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Flexural surfaces
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Annular, coin-shaped lesions
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1) Harsh chemicals/soaps 2) Excessive nathing/dry skin 3) Foods that worsen 4) Pet dander 5) Excessive heat
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1)Topical steroids 2) Topical immunosuppressants (Elidel and Protopic) 3) UV light 4) Antihistamines
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Affects >90% of the population, MC in adolescents
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Non-inflammatory and inflammatory
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Comedones - blackheads (open) and whiteheads (closed)
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Papules/pustules (superficial) and cysts/nodules (deep)
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1) Skin cells plug hair follicle 2) Excess sebum 3) Bacteria (P. Acnes) 4) Inflammation
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Topical abx (clindamycin, erythromycin), high resistance - need to use benzoyl peroxide to prevent resistance
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Oral isotretinoin (accutane, sotret, claravis, amnesteem)
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Acne Fulminans. High levels of testosterone and P. acnes
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Erythema, rosacea
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1) Vascular 2) Acne 3) Phymatous 4) Occular
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Vascular, facial redness that spares the periorbital area
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Papules and pustules w/ central facial redness and telangiectasias
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Skin thickening and irregular surface
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MC the nose (rhinophyma), also chin, forehead, eyelids
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Only tx is surgery
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Usu. chronic blepharitis and conjunctivitis, dryness, sting/burning of eyes
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Sun, alcohol, heat, exercise, spicy foods, alcohol