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Hidradenitis Suppurativa |
Only after puberty |
Sinus tracts |
1) Women 2) AA 3) h/o acne 4) Tight, curly hair (ingrown) 5) Obesity 6) Tight clothing |
1) I&D 2) PO or topical abx 3) Bleach baths 4) Laser 5) Accutane |
Bullous Pemphigoid |
IgG autoantibodies bind to the basement membrane leading to separation of dermis from epidermis |
Unknown |
Rare. Onset usu. >65yo, men = women |
Tense bullae that heal /s scarring |
Fleural surfaces |
1) Topical steroids 2) Long-term oral prednisone 3) Tertacycline 4) Methotextrate 5) Immunosuppressants |
Vitiligo |
20yo |
Sharply circumscribed white patches that become confluent. MC face, neck, scalp. |
Unknown. Autoimmune, some genetic inheritance. |
1) Topical steroids 2) Topical immunomodulators (protopic, Elidel) 3) UV 4) Laser 5) Oral steroids 6) Depigmentation 7) Surgery |
Dermatitis herpetiformis |
30's |
Very pruritic, burning sensation, erythematous excoriated papules or plaques and herpetiform lesions |
Elbows, knees, and buttock. Palms and soles are spared. |
Biopsy |
1) Gluten free diet 2) Dapsone |
Hemolysis, methemoglobinemia, peripheral neuropathy, cross rxn w/ sulfa allergy |
lymphoma and intestinal CA |
Psoriasis |
Autoimmune. Fast turnover of dermal cells - 3 to 5 days (normal 23days) |
Elbows and knees. Plaque psoriasis. |
1) Plaque 2) Guttate 3) Inverse 4) Pustular 5) Erythrodermic |
<1cm "dew drop" plaques all over the body. |
Young, healthy people. Typicalll /p strep infection. |
Moist, "beefy red", not scaly. Occurs in skin folds, axillae, groin. |
palms and soles |
Generalized erythema and scale. |
No |
Koebner phenomenon |
NSAIDS, Lithium, Inderal, Indomethacin, anti-malarials, beta blockers |
psoriatic arthritis |
Topical and intranasal steroids |
1) UV 2) Biologics (Enbrel, Humira, Amevive, Remicade, Raptiva) 3) Methotextrate 4) Cyclosporin |
Vitamin D analogue (Dovonex, Vectical) |
Pityriasis Rosea |
15-40yo. Trunk. |
Collarette of fine scale OR Christmas tree pattern that is symmetric and gen. on trunks and extremities |
Viral. Spring and Fall. |
None - self limiting 8-12wks. UV can help, mild topical steroids PRN. |
Asthma and allergies |
The itch that rashes |
Red papules or plaques with scale, lichenification |
Flexural surfaces |
Annular, coin-shaped lesions |
1) Harsh chemicals/soaps 2) Excessive nathing/dry skin 3) Foods that worsen 4) Pet dander 5) Excessive heat |
1)Topical steroids 2) Topical immunosuppressants (Elidel and Protopic) 3) UV light 4) Antihistamines |
Affects >90% of the population, MC in adolescents |
Non-inflammatory and inflammatory |
Comedones - blackheads (open) and whiteheads (closed) |
Papules/pustules (superficial) and cysts/nodules (deep) |
1) Skin cells plug hair follicle 2) Excess sebum 3) Bacteria (P. Acnes) 4) Inflammation |
Topical abx (clindamycin, erythromycin), high resistance - need to use benzoyl peroxide to prevent resistance |
Oral isotretinoin (accutane, sotret, claravis, amnesteem) |
Acne Fulminans. High levels of testosterone and P. acnes |
Erythema, rosacea |
1) Vascular 2) Acne 3) Phymatous 4) Occular |
Vascular, facial redness that spares the periorbital area |
Papules and pustules w/ central facial redness and telangiectasias |
Skin thickening and irregular surface |
MC the nose (rhinophyma), also chin, forehead, eyelids |
Only tx is surgery |
Usu. chronic blepharitis and conjunctivitis, dryness, sting/burning of eyes |
Sun, alcohol, heat, exercise, spicy foods, alcohol |