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South College
Phys Test #3
54
Physiology
Graduate
12/03/2008

Additional Physiology Flashcards

 


 

Cards

Term

What are the laboratory findings in polycythemia vera?

a.       Decreased hemoglobin and/or hematocrit; increased RBC’s and granulocytes; decreased platelets

b.      Increased hemoglobin and/or hemoglobin; increased RBC’s, granulocytes, and platelets

c.       Normal hemoglobin and hematocrit; normal RBC’s; increased granulocytes and platelets

d.      Increased hemoglobin and/or hematocrit; increased RBC’s; decreased granulocytes and platelets

Definition
d. Increased hemoglobin and/or hematocrit; increased RBC’s; decreased granulocytes and platelets
Term

Which statement is most correct regarding erythropoietin?

a.       Erythropoietin is mainly secreted by the liver

b.      Injection of erythropoietin leads to a rapid increase in the number of circulating RBC’s within the next 48 hours. 

c.       Excessive x-ray exposure with destruction of the bone marrow leads to an increased erythropoietin secretion.

d. Erythropoietin acts on the spleen by decreasing RBC destruction.
Definition

c.       Excessive x-ray exposure with destruction of the bone marrow leads to an increased erythropoietin secretion.

Term

What is the safest and least expensive treatment for patients with polycythemia vera?

a.       High altitude

b.      Decrease of iron levels

c.       Therapeutic phlebotomy

d. Decrease of erythropoietin levels
Definition

c.      Therapeutic phlebotomy

Term

A patient with a sore on his lip visits his physician.  Examination found no pain or drainage from the sore.  The patient was subsequently admitted to the hospital with a fever.  Laboratory results showed the following values: hematocrit of 34%, platelet count of 300,000/µl, and white blood cell (WBC) count of 4200/µl, with 68% lymphocytes and 20% neutrophils.  What is the diagnosis for this patient?

a.       A mild, nontreatable infection

b.      Agranulocytosis

c.       Aplastic anemia

d.      Acute leukemia

e.      Hemolytic anemia

Definition
b. Agranulocytosis
Term

A 20-year old man presents to the emergency department with a 2-week history of diarrhea after a trip out of the county.  He is admitted to the hospital for dehydration.  His stool specimen is positive for parasitic eggs.  Which type of WBC’s would have elevated numbers?

a.       Eosinophils

b.      Neutrophils

c.       T lymphocytes

d.      B lymphocytes

e.      Monocytes

Definition

a.       Eosinophils

Term

What occurs after activation of basophils?

a) Decreased diapedesis of neutrophils     

b)Decreased ameboid motion

c) Contraction of blood vessels

d) Increased capillary permeability

 

Definition

d) Increased capillary permeability

Term

Neutrophils are capable of all of the following except which funtion?

a)diapedesis

b)phagocytosis of whole red blood cells

c)ameboid motion

d)production of proteolytic enzymes for digestion of bacteria

Definition

b)phagocytosis of whole red blood cells

Term

Basophils share functional and morphological charactereistics with

a)monocytes

b)macrophages

c)mast cells

d)myelocytes

Definition

c)mast cells

Term

What causes the release of histamine in an allergic reaction

a)The binding of IgM to basophils      

b)The binding of IgE to mast cells

c)The releasae of histamine by helper T cells

d)The free radical stimultion of endothelial cells

Definition

b)The binding of IgE to mast cells

Term

Circulating antibodies are secreted mainly by

a)Helper T lymphocytes

b)Suppressor T lymphocytes

c)Dormant B lymphocytes

d)Plasma cells

e)Killer T lymphocytes

Definition

d)Plasma cells

Term

What causes tolerance to one’s own body?

a. lack of antigens on cells

b. lack of receptors on lymphocytes to antigens

c. loss of lymphocytes reactive to native agents

d. activation of suppressor cells

Definition

c. loss of lymphocytes reactive to native agents

Term

In sensitized person’s, immediate hypersensitivity responses are primarily the result of liberation of vasoactive substances by the action of which of the following?

a. Activate T lymphocytes on smooth muscle cells

b.  IgA on basophils and mast cells

c. IgA on neutrophils and eosinophils

D. IgE on basophils and mast cells

e. IeG on neutrophils and eosinophils

Definition

D. IgE on basophils and mast cells

Term

What is the proper pathway for the extrinsic clotting pathway?

a. Contact of blood with collagen, formation of prothrombin activator, conversion of prothrombin into thrombin and conversion of fibroginogen into fibrin threads

B. Tissue trauma, formation of prothrombin activator, conversion of prothrombin into thrombin and conversion of fribrogen into fibrin threads

c.  Activation of platelets, formation of prethrombin activators, conversion of preothrombin into thrombin, and conversion of fibroginen into fibrin

d.  Trauma
Definition

B*. Tissue trauma, formation of prothrombin activator, conversion of prothrombin into thrombin and conversion of fribrogen into fibrin threads

Term

What condition leads to deficiency in factor 9, which can be corrected by an intravenous injection of vitamin K?

a.  Classis hemophilia

b. Hepatitis B

C. Bile duct obstruction

d. Genetic deficiency in antithrombin 3

Definition

C*. Bile duct obstruction

Term
A 2 year old boy bruises easily and has a history of nose bleeds,  His physical exam shows several small bruises you suspect the patient has deficiency in what number coagulation factor
Definition
factor 8
Term

All of the following statements regarding heparin are correct except:

A. Heparin acts by increasing the effectiveness of antithrombin III

B. The concentration of heparin in the blood is normally very slight

C. Heparin can be an effective anticoagulant even in the absence of antithrombin III

D. Heparin is a powerful anticoagulant

E. Heparin can be produced and released by basophils and mast cells

Definition

C. Heparin can be an effective anticoagulant even in the absence of antithrombin III

Term

Which of the following is a function of thrombin?

                A. Activation of Factor XIII to stabilize fibrolysis

                B. Conversion of Factor VII to VIIa

                C. Conversion of fibrinogen to fibrin

                D. Enhancement of Factor V, VIII, and XI activity

Definition

C. Conversion of fibrinogen to fibrin

Term

A patient with a platelet count of 212 x10^3 /ul and a bleeding time of 12 minutes. These results suggest which condition?

                A. Decreased platelet production

                B. Defective platelet function

                C. Increased platelet production

                D. Increased platelet destruction

Definition
B. Defective platelet function
Term

Which of the following conditions does not result in an increased bleeding tendency?

                A. Liver disease

                B. Vitamin A deficiency

                C. Warfarin overdoes

                D. Chronic aspirin medication

Definition
B. Vitamin A deficiency
Term

The excessive bleeding of a person with hemophilia A (i.e. classic hemophilia) is usually caused by

                A. Excessive endogenous secretion of heparin

                B. A genetic lack of Factor VIII

                C. An inability to absorb vitamin K

                D. Severe Pulmonary disease.

Definition
B. A genetic lack of Factor VIII
Term

Which one of the following most likely is associated with a decrease in circulating erythropoietin concentration?

a. moving from sea leavel to high altitude

b. decreased renal mass

c. chronic intestincal blood loss

d. severe pulmonary disease

Definition

b. decreased renal mass

Term

Which one of the following most likely is associated with a decrease in the concentration of reticulocytes (newly released blood cells) in the peripheral blood

a. chronic blood loss

b. bone marrow aplasia

c. hemolytic anemia

d. moving from sea level to a high altitude

Definition

b. bone marrow aplasia

Term

A 64 year old male patient develops a macrocytic anemia after surgery to remove a large part of his stomach. Which one of the following is most likely the cause of this patient’s problem.

a. poor absorption of dietary iron

b. hereditary spherocytosis

c. hemolytic anemia

d. inadequate vitamin B12 absorption

Definition

d. inadequate vitamin B12 absorption

Term

Which one of the following best represents the primary form in which iron is transported in the plasma?

a. intrinsic factor

b. ferritin

c. transferrin

d. hemosiderin

Definition

c. transferrin

Term