Term
| hypersecretion of the adrenal cortex may result in the production of excess amounts of corticosteroids particularly glucocorticoid |
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Definition
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Term
| the condition that results from excess cortisol |
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Definition
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Term
| endogenous causes of cushing syndrome |
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Definition
| corticotropin secreting pituitary tumors, corisol secreting neoplasm within the adrneal glands, excess secretion of corticotropin by a carcinoma of the lung or other tissues |
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Term
| excessive production of ACTH because of a pituitary tumor is called |
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Definition
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Term
| the single exogenous cause of cushing syndrome is prologed administration of high doeses of |
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Definition
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Term
| hyperadrenalism produces marked changes in the personal appearance of the affected person including |
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Definition
| obesity, facial redness, hirsutism, menstrual disorders, hypertension of varying degrees, and muscle wasting of the extremities |
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Term
| additional findings of cushing syndrome |
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Definition
| delayed wound healing, insomnia, irrational ehavior and mood disturbances |
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Term
| hallmark findings that lead to diagnosis of cushing disease |
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Definition
| truncal obesity, protein wasting, facial fullness, purple striae on the abdomen, breast buttocks or thighs, osteoporosis, hypokalemia |
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Term
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Definition
| polycythemia, hypokalemia, hypernatremia, hyperglycemia, leukocyotsis, glycosuria, hypocalcemia, elevated plasma cortisol |
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Term
| an example of an aldosterone antagonis |
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Definition
| spironolactone (aldactone) |
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Term
| a cytotoxic substance that is used as a palliative treatment of inoperable adrenal tumors |
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Definition
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Term
| agents that interfere with cortisol production |
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Definition
| metyrapone (metopirone), aminoglutethimide(cytadren), ketoconazole(nizoral) |
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Term
| metyrapone is also used in combination with _________ for enhanced effects |
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Definition
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Term
| minor symptoms such as ____ can indicate the onset of a potentially serious infection |
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Definition
| low grade fever, sore throat or aches |
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