Term
| adrenal insufficiency may be classified as either |
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Definition
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Term
| frequently the result of a destructive disease process affecting the adrenal glands that causes deficiencies of cortisol and aldosterone |
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Definition
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Term
| the most common cause of addison disease |
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Definition
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Term
| an autoimmune disease in which adrenal tissue is destroyed by antibodies formed by th patient's own immune system |
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Definition
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Term
| other causes of addison disease |
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Definition
| tb, hemorrhage r/t aticoagulant therapy, fungal infections, AIDS, metastatic cancer, gram-negative sepsis, adrenalectomy, adrenal toxins and abrupt withdrawal of exogenous steroids |
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Term
| secondary adrenal insufficiency is a result of dysfunction of the ______ or pituitary, which leads to decreased ________ |
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Definition
| hypothalamus, androgen and cortisol production |
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Term
| insufficiency of adrenocortical steroids causes defects associated with the loss of |
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Definition
| mineralocorticoids and glucocorticoids |
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Term
| may result from accelerated sodium and water excretion |
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Definition
| hypovolemia and hyponatremia |
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Term
| other manifestations of adrneal insufficiency |
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Definition
| progressive weakness, lethargy, unexplained abdominal pain and malais, skin hyperpigmentation, pressure points, joints, creases of the body |
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Term
| life threatening emergency that usually results form a sudden marked decrease in available adrenal hormones |
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Definition
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Term
| priciptating factors of addisonian crisis |
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Definition
| adrenal surgery, pituitary distruction, abrupt withdrawal of steroid therapy, stress |
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Term
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Definition
| infection, illness, trauma, emotional or psychiatric disturbances |
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Term
| manifestations of addisonian crisis include more sever symptoms of meneralocorticoid and glucocorticoid deficiency |
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Definition
| hypotension, tachycardia, dehydration, confusion, hyponatremia, hyperkalemia, hypercalcemia, hypoglycemia |
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Term
| if addisonian crisis is left untreated f&e imbalances can lead to |
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Definition
| circulatory collapse, cardiac dysrhythmias, cardiac arrest, coma and death |
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Term
| Addison disease is diagnosed on the basis of clinical manifestions and a lab findings including |
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Definition
| low serum and urinary cortisol level, decreased fasting glucose, hyponatremia, hyperkalemia and increased BUN |
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Term
| the most commonly used replacement hormone |
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Definition
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Term
| glucocorticoids usually peak in the early_____ and are at their lowest level in the _______ |
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Definition
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Term
| secondary adrenal insufficiency is itreated with |
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Definition
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Term
| addisonian crisis is treated with |
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Definition
| IV fluids, hydrocortisone, electrolytes, and dextrose |
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Term
| details of health history that are relevant to addison disease are |
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Definition
| weight loss, salt cravin, n/v, abdominal cramping and diarrhea, muscle weakness and aches, poor stress response, decresed libido and amenorrhea |
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Term
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Definition
| pale skin with bronzed areas, emaciation, sparse body hair, poor skin turgor, hypotension and muscle wasting |
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Term
| salt is not restricted because pt with addison disease tend to lose |
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Definition
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