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VVC Microbiology
Microbiology Chapter 22 Pathogenic Fungi
32
Microbiology
Undergraduate 2
06/02/2013

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Term
Mycoses
Definition
Mycoses - Fungal diseases
Term
Fungi are often resistant to .....
Definition
antifungal agents
Term
Mycoses are acquired by
Definition
inhalation, trauma, or ingestion
Term
Most mycoses are not contagious except ....
Definition
Dermatophytes (candida & pneumocystis
Term
List (4) pathogenic fungi
Definition
Blastomyces
Coccidiodes
Histoplasma
Paracoccidioides
Term
Factors for opportunistic mycoses
Definition
Invasive medical procedure
Medical therapies
Certain disease conditions
lifestyle factors
Term
Dermatophytes occur?
Definition
on skin and nails
Term
Toxicoses
Definition
Toxicoses - disease condition due to poisoning (eating mushrooms)
Term
Sabouraud dextrose agar
Definition
used to culture fungi
Term
Fungi often resist ?
Definition
T-cell mediated immune response
Term
What is more similar to human cell, fungi or bacteria?
Definition
fungi
Term
Antifungal drugs often target which part of fungi?
Definition
ergosterol which is only produced by fungi(not found in humans and plant cells)
Term
Amphotericin B
Definition
is an antifungal drug treats Histoplasmosis, Blastomycosis, and Paracoccidioidomycosis
Term
Opportunistic fungal infections require 2 step treatment
Definition
High dose - reduces fungal pathogen
low dose - maintenance therapy
Term
Antifungal vaccines are difficult because
Definition
fungal metabolism is similar to our own
Term
There are fungal vaccines for ?
Definition
Coccidioides
Candida
Blastomycosis
Term
Fungal infections usually begin as
Definition
pulmonary infection
Term
Histoplasmosis Capsulatum
Definition
most common pathogenic fungi found in soil with high nitrogen levels, Eastern US, Africa, Asia
Term
Chronic pulmonary histoplasmosis
Definition
severe cough
Term
Chronic cutaneous histoplasmosis
Definition
skin lessions
Term
Systemic histoplasmosis
Definition
affects spleen and liver
Term
Ocular histoplasmosis
Definition
Type I hypersensitivity to eyes
Term
Blastomycosis
Definition
pathogenic fungi found in soil with rich organic matter, in eastern US and Canada
Term
Cutaneous Blastomycosis
Definition
infection on skin, face, and upper body
Term
Osteoarticular Blastomycosis
Definition
infection in the joints
Term
Meningitis Blastomycosis
Definition
inflammation of meninges
Term
Spherule
Definition
fungal parasitic form
Term
Coccidioidomycosis
Definition
pathogenic fungi found in southwest US in desert soil, rodent burrows, remains, and mines
Term
Arthroconidia
Definition
fungal spores
Term
Paracoccidioidomycosis
Definition
pathogenic fungi found in US and Mexico affecting farm workers, causes chronic inflammatory disease
Term
Ketoconazole
Definition
antifungal drug used to treat Paracoccidioidomycosis
Term
(5) types of Opportunistic Fungi
Definition
Pneumosystis
Candida
Aspergillus
Crytococcus
Mucor
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