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testing meds
HTN test II
37
Pharmacology
Graduate
10/16/2010

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Cards

Term
hydrochlorothiazide
Definition
"microzide" diuretic thiazide, 12.5-25 mg qd HTN
Term
C/I of THaizide
Definition
hypersensitivity, anuria, renal decomposition, pregnancy
Term
A/E of thiazides
Definition
hypokalemia, hypomagnesemia, hyperuricemia, mild increase in cholesterol & TG, hypotension
Term
Furosemide
Definition
"Lasix" LOOP diuretic 10-160 mg/day 1-2 divided doses HTN
Term
C/I of Loop diuretic "Lasix"
Definition
hypersensitivity anuria
Term
A/E of Loop Diuretic lasix
Definition
hypokalemia, hypomagnesemia, overdiuresis, metabolic alkalosis
Term
atenolol
Definition
"tenormin" Beta blocker 25-100 mg qd OLOL, HTN
Term
C/I of atenolol "tenormin"
Definition
hypersensitivity, sinus bradycardia, sinus node dysfunction, heart block greater than 1st degree, cardiogenic shock, uncompensated cardiac failure, pulmonary edema, pregnancy
Term
A/E of Beta blockers
Definition
may aggravate asthma or other lung diseases, may cause fatiuge, insomnia, depression, nightmares, bradycardia, ED, aggravate peripheral vascular disease, mask signs of hyperglycemia, mild decrease in HDL, & mild increase in LDL
Term
Lisinopril
Definition
"prinivil" or "Zestril" 5-401mg qd ACE-I, PRIL, HTN
Term
C/I of ACE-I
Definition
hypersensitivity, ANGIOEDEMA, 2nd or 3rd trimester of pregnancy
Term
A/E of ACE-I
Definition
hyperkalemia, COUGH, hypotension, rash, ANGIOEDEMA, acute renal failure in patients with bilateral renal artery stenosis or significant dehydration
Term
Amlodipine
Definition
"Norvasc" CCB, 2.5-10 mg qd, HTN, DIPINE
Term
C/I of CCB
Definition
Hypersensitivity
Term
A/E of CCB
Definition
peripheral edema, flushing. palpitation, headache, dizziness, eczema in elderly, tachycardia
Term
Atorvastatin
Definition
"lipitor" HMG CoA reductase inhibitor, STATIN 10mg qd, Hyperlipidemia
Term
C/I of statin
Definition
hypersensitivity, active liver disease, pregnancy, breast feeding, unexplained persistant elevations of serum transaminases, use of CSA, gemfibrozil, niacin
Term
A/E of statin
Definition
hepatic toxicity, myopathy, neuropathy
Term
fenofibrate
Definition
"tricor" fibric acid, 145 mg qd, hyperlipidemia
Term
C/I of fenofibrate
Definition
hypersensistivity hepatic dysfunction (primary biliary cirrhosis, unexplained persistent liver function abnormalities) severe renal dysfunction, preexistin gallbladder disease
Term
A/E of fenofibrate
Definition
gi complaints, bile lithogenicity (stones)
Term
Nicotinic Acid
Definition
"Niacin" Niacor, "niaspan", 1-2 gm tid, hyperlipidemia
Term
C/I of Niacin
Definition
liver disease, Type II DM, gout, hyperuricemia
Term
A/E of niacin
Definition
flushing, glucose intolerance, increase in uric acid, fulminant hepatitis
Term
Digoxin
Definition
"lanoxicaps" "lanoxin", anti-arrhythmic, A-FIB& CHF, loading dose 10-15 mcg/kg over 12-24 hrs, then 0.125-0.5 mcg qd
Term
C/I DIgoxin
Definition
hypersensitivity, V-FIB, stress & exercise (increase sympathomimetic tone)
Term
A/E of Digoxin
Definition
Drug interactions w/quinidine, verapamil, amiodarone
Term
Nitroglycerin
Definition
"minitran" SL 0.2-0.6, (usual dose 0.4) every 5 minutes for 15, prophy 5-10 minutes prior to activity that may provoke attack
Term
C/I of NTG
Definition
IV USE: hypotension, uncorrected hypovolemia, inadequate cerebral circulation, constrictive pericarditis or tamponade, ALL- hypersensitivty to isosorbide, concurrent use with PDE-5 Inhibitors, glaucome, head trauma or cerebral hemorrage, severe anemia
Term
A/E of NTG
Definition
Cardio:Hypotension, cresendo angina, flushing, peripheral edeam, postural hypotension, tachycardia, CNS:headache, syncope/dizzy, GI:bowel incontinenct, N&V, xerostomia, Urinary incontinence, blurred vision, diaphoresis
Term
Warfarin
Definition
"coumadin" anticoagulant, 4-5 mg qd, thromboembolitic disorders
Term
C/I of warfarin
Definition
hypersensitivity, hemorrhage, alcoholism, surgery, dental work, spinal anesthesia or spinal injections, pregnancy
Term
A/E of warfarin
Definition
hemorrhage, skin necrosis, purple toe syndrome
Term
monitoring Diuretics
Definition
blood pressure
BUN/serum creatinine
serum electrolytes (K+, Mg2+, Na+)
uric acid (for thiazides)
Term
monitoring β-Blockers
Definition
blood pressure
heart rate
Term
monitoring Aldosterone antagonists
ACE inhibitors
Angiotensin II receptor blockers Direct Renin inhibitors
Definition
blood pressure
BUN/serum creatinine
serum potassium
Term
Calcium channel blockers
Definition
blood pressure
heart rate
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