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SLE115 Exam Revision, Deakin
N/A
20
Pharmacology
Undergraduate 1
06/16/2014

Additional Pharmacology Flashcards

 


 

Cards

Term
Xenobiotic
Definition
any foreign substance taken into the body, it may produce beneficial effects or they may be toxic
Term
Toxicant
Definition
Substances that produce adverse biological effects
Term
Ultimate Toxicant
Definition
Toxic metabolites of an xenobiotic
Term
Toxins
Definition
Specific proteins produced by living organisms that exhibit acute (immediate) effects
Term
Poisons
Definition
Toxicants that cause immediate death or illness when exposed to small amounts
Term
Drugs can be classified by-
Definition
Source
chemical formula
mode of action
therapeutic use
system acted upon
Term
Drug
Definition
A chemical substance that has actions on living tissue
Term
Exposure Dose
Definition
amount of xenobiotic encounted in the environment
Term
Absorbed dose
Definition
The actual amount of the exposed dose that enters the body
Term
Administered Dose
Definition
Dose which is administered
Term
Factors affecting bio availability
Definition
Absorption, Distribution, Metabolism, Excretion
Term
Excretion
Definition
pertains to the elimination or ejection of the xenobiotic substance and its metabolites by specific excretory organs
Term
Biotransformation
Definition
pertains to the removal of the absorbed xenobiotic substances and its metabolites by the metabolism
Term
Detrification
Definition
most xenobiotics introduced into the body undergo chemical changes which render them less toxic
Term
Bioactivation
Definition
most xenobiotics introduced into the body undergo chemical changes which render them more toxic after biotransformation
Term
Drug Metabolism
Definition
changes the chemical structure and proberties of chemical comounds
Term
RHO HID in Phase 1
Definition
reduction, hydrolysis, oxidisation, hydration, isomerisation, dehalogenation
Term
Phase 2, what occurs
Definition
Some products of phase 1 metabolism and conjugated to hyrophillic side groups
Term
Impact Factor
Definition
Score of how often journal articles are cited in other publications
Term
N Value
Definition
Sample size
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