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Salivary Glands
Oral Histology Final
58
Histology
12/01/2011

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Term
What are the six functions of saliva?
Definition
protection
buffer
digestion
taste
antimicrobial action
tooth integrity
Term
what is the active component for taste?
Definition
gustin
Term
what are the active components for antimicrobial action?
Definition
IgA
glycoproteins
lysozymes
lactoferrin
Term
what are the active components of tooth integrity?
Definition
calcium
phosphate
fluoride
statherin
Term
what are the major glands?
Definition
parotid
submandibular
sublingual
Term
what are the minor glands?
Definition
glossopalatine
lingual (anterior and posterior)
palatal
labial and buccal
Term
Major glands are located ___ from their secretory surface and have ___ secretory ducts while minor glands are located ___ the submucosa and have ___ secretory ducts.
Definition
far
long
within
short
Term
___ secretions are thin, watery and protein rich (enzymatic and non enzymatic) with small amounts of polysaccharides (amylase, glycoproteins)
Definition
serous
Term
___ secretions are thick ropey viscous rich in polysaccharides and having small amounts of protein (generally non enzymatic) - mucins.
Definition
mucous
Term
____ produce both types of secretions.
Definition
mixed
Term
___ gland is located along the posterior aspect of the ramus of the mandible.
Definition
parotid
Term
the parotid duck (____) pierces the ___ muscle and enters the oral cavity opposite the upper second molar tooth (parotid papilla).
Definition
Stenson's
buccinator
Term
the ___ ___ is the parotid gland opening and is hard and enlarged.
Definition
parotid papilla
Term
The ____ gland curves around the posterior aspect of the mylohyoid muscle. it has superficial and deep heads.
Definition
submandibular
Term
the submandibular duct (_____) opens at the sublingual ___.
Definition
Wharton's
caruncle
Term
the __ gland is the smallest major salivary gland and it lies in the sublingual fold.
Definition
sublingual
Term
the major portion of the sublingual gland has a single duct (_____) which shares an opening with the ____ gland.
Definition
Bartholin's
submandibular
Term
minor sublingual glands have openings along the sublingual fold, ducts of ___.
Definition
Rivinus
Term
what are the 6 developmental stages of a salivary gland?
Definition
1. induction
2. formation and growth of epithelial cord
3. initiation of branching
4. repetitive branching of the epithelial cord
5. canalization
6. cytodifferentiation
Term
during induction of salivary glands, ___ induces the proliferation of the epithelium and a ___ is found amid a condensed mesenchyme,
Definition
mesenchyme
bud
Term
the initial ducts are ____ (lying between acini and striated ducts)
Definition
intercalated
Term
____ ducts are larger and in the connective tissue septa.
Definition
interlobular
Term
serous acinar cells are ___ or pyramidal in shape. they have extensive rER, a well developed Golgi and numerous secretory granules.
Definition
columnar
Term
mucous cells are found in ____ acini. they have extensive rER and Golgi, numerous secretory granules, and have secretions granules that contain much __.
Definition
tubular
carbohydrate
Term
serous demilune cells are ___ shaped and are similar to serous cells.
Definition
crescent
Term
myoepithelial cells are ___ shaped around acini and ___ shaped around intercalated ducts.
Definition
basket
spindle
Term
myoepithelial cell are ___ and maintain acinar structural __.
Definition
contractile
organization
Term
myoepithelial cells lie inside the basal lamina because they are ___ cells.
Definition
epithelial
Term
___ duct cell is a single layer of squamous to cuboidal cells.
Definition
intercalated
Term
the intercalated duct is primarily a ___. it may modify saliva by secretory and resorptive processes. they are ___ cells for regeneration.
Definition
conduit
stem
Term
____ duct cells are NOT present in minor glands or other exocrine glands.
Definition
striated
Term
____ duct cells are a single layer of columnar cells that possess basal striations with many ___.
Definition
striated
mitochondria
Term
striated duct cells reabsorb __, ___ and some proteins. They secrete __, ___, ___.
Definition
Na+
Cl-
K+
HCO3-
glycoproteins
Term
___ duct cells are pseudostratified epithelium with goblet cells, ciliated cells, and columnar cells.
Definition
excretory
Term
excretory duct cells reabsorb ___.
Definition
Na+
Term
the ____ gland is a pure serous gland that produces about 25% of the total saliva. it has long intercalated and striated ducts.
Definition
parotid
Term
____ ____ are serous cells capping a mucous end piece.
Definition
serous demilunes
Term
___ ensure proper folding and post-translational modifications
Definition
chaperones
Term
strong emotional stimuli and cause ___ mouth or __ salivary secretions. certain odors or tastes can stimulate secretion.
Definition
dry
increase
Term
____ stimulation produces less profuse and more protein-rich and mucus-rich secretion. the neurotransmitter is ___; ___ receptors.
Definition
sympathetic
norepinephrine
adrenergic
Term
_____ stimulation produces profuse watery secretion. the neurotransmitter is ___ ; ____ receptor.
Definition
parasympathetic
acetylcholine
cholinergic
Term
norepinephrine binds to ____ receptors, causing __ proteins to activate __ which activates ____ causing a phosphorylation cascade. secretory stimulus causes granules to fuse with the luminal plasma membrane and release contents.
Definition
beta adrenergic
G
cAMP
PKA
Term
acetylcholine binds to __ ___ receptors which activate ____ __ forming ___ which causes the release of ___ from intracellular stores causing an osmotic gradient, ion exchange and water transport channels, ___.
Definition
muscarinic cholinergic
phospholipase C
IP3
Ca++
aquaporins
Term
saliva modification in ducts occurs at secretory endpieces and ____ ____. primary saliva is ___.
Definition
intercalated ducts
isotonic
Term
final saliva is ___
Definition
hypotonic
Term
parotid glands contribute ___%, their striated ducts are ___ and their intercalated ducts are ___ and __.
Definition
25
long
long and narrow
Term
submandibular glands contribute ___%, their striated ducts are ____ and their intercalated ducts are ___ ___ ___.
Definition
60
longest
shorter than parotid
Term
sublingual glands contribute ___%, their striated ducts are ___ ___ and their intercalated ducts are ___.
Definition
5
very short
inconspicous
Term
the minor glands contribute an additional __-__%
Definition
5-10
Term
______ Law states that composition changes with changes in flow rates.
Definition
Heidenhains
Term
increased flow rate allows ___ changes since it decreases the time available for reabsorption and secretion. also in glands with longer ducts there is more surface area and more time for modification of saliva.
Definition
fewer
Term
IgA is dimeric and produced by mucosal ___cells.
Definition
plasma
Term
igA binds to a receptor (secretory component) located on the ___ membrane.
Definition
basal
Term
true or false
saliva is a way to measure drug levels.
Definition
true
Term
true or false
saliva also protects soft tissue from infection and inflammatory reactions
Definition
true
Term
when someone has xerostomia, the oral mucosa may becomes inflamed (____) and caries progress very rapidly.
Definition
mucositis
Term
salivary gland stones =
Definition
sialoliths
ranula
Term
___ glands are found in the floor of mouth adjacent to the mandible in the sublingual fossa. these glands are palpated using fingers of both hands. the extra oral fingers provide a firm surface allowing one to feel for irregularities
Definition
sublingual