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PTherapeutics I T3 COPD
COPD
26
Pharmacology
Professional
04/25/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
"Blue Bloaters" is associated with which COPD subset?
Definition
Chronic Bronchitis
Term
"Pink Puffers" is associated with which COPD subset?
Definition
Emphysema
Term
Pink puffers are defined by_____
Definition
anatomic pathology
Term
blue bloaters are defined by ______
Definition
clinical presentation
Term
An increase in ____stress aggravates COPD
Definition
oxidative
Term
An imbalance of _______ is a portion of the pathophysiology behind COPD
Definition
proteinases and anti-proteinases
Term
The pathologic changes seen in COPD are_____
Definition
parenchyma, Vascular, and mucus hypersecretion
Term
The only proven way to slow loss of lung function in COPD patient is______
Definition
smoking cessation
Term
_____are the cornerstone of COPD therapy
Definition
bronchodilators
Term
If COPD is mild, first line medication(s) is/are_______
Definition
SABA or SAAC.
Also, combo product: Combivent (Albuterol/ipratropium)
Term
In moderate to severe COPD, _____ may be added.
Definition
LABA or LAAC.
Term
What are the SABAs?
Definition
Levalbuterol & albuterol
Term
What are the LABAs?
Definition
Formoterol, Salmeterol and Arformoterol (Brovana)
Term
What are the SAACs?
Definition
Ipratropium, Oxitropium (oxivent)
Term
What are the LAACs?
Definition
Tiotropium
Term
_____are good for nocturnal symptoms.
Definition
LABAs
Term
Tiotropium (spiriva) has _____ systemic absorption and an half life elimination of _____
Definition
poor; 5-6 days
Term
LABAs have_____ dosing
LAACs have ____ dosing
Definition
12 hour
QD
Term
Which medication has the SEs of Upper RTI, dyspepsia, and xerostomia?
Definition
Tiotropium (spiriva)
Term
The airflow improvement provided by ICSs is______
Definition
modest
Term
Which therapy is better in terms of FEV1, health status, and frequency of exacerbations?
Definition
combo tx vs mono tx
incl Advair and Symbicort
Term
Systemic CCs may be used ___-term for exacerbations. With chronic therapy, risk (does not increase, decreases, increases)
Definition
short; increases
Term
Oral corticosteroids should be tapered if used longer than_____
Definition
14 days
Term
If IV systemic corticosteroids are used, they should be______
Definition
changed to oral after improvement in pulmonary status.
Term
When treating with O2, titrate until _______
Definition
saturation >90%
Term
Which cells are involved with COPD?
Definition
CD8+, Neturophils and macrophages
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