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PTherapeutics I T2 Alzheimer's Dx
Alzheimer's non-drug questions
18
Pharmacology
Professional
04/04/2011

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Cards

Term
Low serum levels of __________ may contribute to alzheimers
Definition
folate and B12
Term
elevated _______ levels may contribute to alzheimers
Definition
Plasma and total homocysteine
Term
A ________ component almost always plays a role in early-onset alzheimers
Definition
Genetic
Term
Late onset alzheimers is related to?
Definition
Apolipoprotein E
Term
The signature lesions seen in alzheimers are_______
Definition
neuritic plaques and neurofibrillary tangles
Term
Neurofibrillary tangles are composed of ______
Definition
abnormally hyperphosphorylated tau protein
Term
________ also leads to the release of other agents which promote inflammation, which may be an attempt to ______ amyloid deposition
Definition
beta amyloid peptide; attempt to clear
Term
A disturbance in written language is?
Definition
Aphasia
Term
An inability to carry out motor activities despite having intact motor function is?
Definition
Apraxia
Term
An inability to recognize/identify objects despite intact sensory function is?
Definition
Agnosia
Term
What is the only definitive method of diagnosis of alzheimers?
Definition
direct exam of brain during autopsy or biopsy to see the plaques and tangles
Term
The serologic evaluation (involved with diagnosis) evaluates?
Definition
LFTs, thyroid, B12, CBCs and electrolytes
Term
What are the two symptoms of alzheimers? Which is less predictable?
Definition
Cognitive and noncognitive (behavioral). Noncognitive is less predictable.
Term
Is mild cognitive impairment enough to warrant a diagnosis of alzheimers?
Definition
no, it is considered a part of normal aging.
Term
what common medications contribute to alzheimers?
Definition
AAABOS:
antipsychotics, anticonvulsants, anticholinergics, BZDs, Opiods, Sedative hypnotics
Term
What should be monitored in Brain Vascular Disease, a risk factor for Alzheimers?
Definition
BP, Glucose, Cholesterol, Homocyestine.
Term
A patient with significant Brain vascular disease should be treated with_______
Definition
low-dose aspirin
Term
What is monitored in a thorough Baseline Assessment?
Definition
Tom Brady Can Fight Pooping:
Thought processes, Behavior, Cognitive status, Functional processes, Physical status
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