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Title: Psych 106

Description: Biopsychology Final

Total Flash Cards: 287

Created: 09/13/2004 17:36:08

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Term
Vertebrate muscle
Definition
Smooth, cardiac and skeletal/ striated muscle.
Term
Smooth Muscle
Definition
Nonstriated muscle innervated by the autonomic nervous system, found in the walls of blood vessels, in the reproductive tracts, in sphincters, within the eye, in the digestive system, and around hair follicles; in intestines, uterus etc...
Term
Cardiac muscle
Definition
The muscle responsible for the contraction of the heart.
Term
Skeletal muscle
Definition
One of the striated muscles attached to bones.
Term
Extrafusal muscle fibers
Definition
One of the muscle fibers responsible for the force exerted by the contraction of a skeletal muscle.
Term
Alpha motor neuron
Definition
Neuron whose axon forms synapses with extrafusal muscle fibers of a skeletal muscle; activates muscle contraction fibers.
Term
Neuromuscular junction
Definition
The synapse between an axon's terminal button and a muscle fiber.
Term
Motor unit
Definition
A motor neuron and its associated muscle fibers.
Term
Motor neuron
Definition
Neuron in central nervous system that controls either the contraction of a muscle or secretion of a gland.
Term
Motor neuron synapse
Definition
Junction between the terminal button of an axon and the membrane of another motor neuron.
Term
Motor endplate
Definition
Postsynaptic membrane of a neuromuscular junction.
Term
Acetylcholine
Definition
Neurotransmitter in the autonomic nervous system which activates/excites skeletal muscles; usually facilitatory in the brain.
Term
Acetylcholine receptor
Definition
Neurtransmitter receptor which divided into two receptor types - nicotinic and muscarinic.
Term
Acetylcholinesterase
Definition
Enzyme that destroys acetylcholine soon after it is liberated by the terminal buttons and thus terminates the postsynaptic potential.
Term
Myasthenia Gravis
Definition
Autoimmune disease caused by the destruction of the nicotinic receptors at the neuromuscular junction; symptoms are progressive weakness and rapid fatigue of the striated muscles; treatment is medicine aimed at inhibiting acetylcholinesterase.
Term
Proprioceptor
Definition
A sensory receptor, found chiefly in muscles, tendons, joints, and the inner ear; detects the motion or position of the body or a limb by responding to stimuli arising within the organism.
Term
Muscle spindle
Definition
Specialized muscle structure innervated by both sensory and motor neuron axons; sends proprioceptive information to the central nervous system and responds to muscle stretching.
Term
Intrafusal muscle fiber
Definition
A muscle fiber that functions as a stretch receptor; arranged parallel to the extrafusal muscle fibers and thus detects changes in muscle length.
Term
Extrafusal muscle fiber
Definition
Muscle fibers that are responsible for the force exerted by contraction of a skeletal muscle.
Term
Gamma motor neuron
Definition
A neuron whose axons form synapses with intrafusal muscle fibers.
Term
Sensory neuron
Definition
Neuron that detects changes in the external or internal environment and sends information about these changes to the central nervous system.
Term
Golgi tendon organ
Definition
The receptor organ at the junction of the tendon and muscle that is sensitive to stretch.
Term
Reflex
Definition
An automatic, stereotyped movement produced as the direct result of a stimulus.
Term
Monosynaptic stretch reflex
Definition
A reflex in which a muscle contracts in response to its being quickly stretched; involves a sensory neuron and a motor neuron, with a synapse in between; uses muscle spindle.
Term
Polysynaptic inhibitory reflex
Definition
A reflex which decreases the strength of muscular contraction when there is danger of damage to the tendons or bones to which the muscles are attached; uses golgi tendon organ.
Term
Flexor
Definition
A type of antigravity muscle which works to flex a limb; the opposite of an extensor.
Term
Extensor
Definition
A type of antagonist muscle which works to straighten a limb; the antagonist of a flexor.
Term
Sensory neurons
Definition
A neuron that detects changes in the external or internal environment and sends information about these changes to the central nervous system.
Term
Interneuron
Definition
A neuron located entirely within the central nervous system.
Term
Somatotopic organization
Definition
A topographically organized mapping of parts of the body that are represented in a particular region of the brain; medial to medial and lateral to lateral.
Term
Ventromedial group
Definition
The four projections from the brain stem to the spinal cord.
Term
Vestibulospinal tract
Definition
Bundle of axons that travels from the vestibular nuclei to the gray matter of the spinal cord; controls postural movements in response to information from the vestibular system.
Term
Vestibular system
Definition
Sensory system which controls our sense of movement, balance and posture.
Term
Tectospinal tract
Definition
A bundle of axons that travels from the tectum to the spinal cord; coordinates head and trunk movements with eye movements.
Term
Reticulospinal tract
Definition
Bundle of axons which travels from the reticular formation to the gray matter of the spinal cord; controls the muscles responsible for postural movements.
Term
Ventral corticospinal tract
Definition
System of axons that originates in the motor cortex and terminates in the ipsilateral ventral gray matter of the spinal cord; controls movements of the upper legs and trunk.
Term
Primary motor cortex
Definition
Region of the cerebral cortex; contains neurons that control skeletal muscle movement.
Term
Rostral
Definition
"Toward the beak"; with respect to the central nervous system, in a direction along the neuraxis toward the front of the face.
Term
Caudal
Definition
"Toward the tail"; with respect to the central nervous system, in a direction along the neuraxis away from the front of the face.
Term
Dorsal
Definition
"Toward the back"; with respect to the central nervous system, in a direction perpendicular to the neuraxis toward the top of the head or the back.
Term
Ventral
Definition
"Toward the belly"; with respect to the central nervous system, in a direction perpendicular to the neuraxis toward the bottom of the skull or the front surface of the body.
Term
Premotor cortex
Definition
Region of the motor association cortex in the lateral frontal lobe; rostral to the primary motor cortex.
Term
Supplementary motor cortex
Definition
Region of the motor association cortex in the dorsal and dorsomedial frontal lobe; rostral to the primary motor cortex.
Term
Motor homunculus
Definition
A deformed map of the body drawn on the primary motor cortex that shows which brain areas control different body parts.
Term
Lateral group
Definition
The corticospinal tract, the corticobulbar tract, and the rubrospinal tract.
Term
Lateral corticospinal tract
Definition
The system of axons that originates in the motor cortex and terminates in the contralateral ventral gray matter of the spinal cord; controls movements of the distal limbs.
Term
Ventral corticospinal tract
Definition
The system of axons that originates in the motor cortex and terminates in the ipsilateral ventral gray matter of the spinal cord; controls movements of the upper legs and trunk.
Term
Corticobulbar tract
Definition
A bundle of axons traveling from the motor cortex to the fifth, seventh, ninth, tenth, eleventh, and twelfth cranial nerves; controls movements of the face, neck, tongue, and parts of the extraocular eye muscles.
Term
Rubrospinal tract
Definition
The system of axons that travels from the red nucleus to the spinal cord; controls independent limb movements.
Term
Lateral
Definition
Toward the side of the body, in a direction at right angles with the neuraxis and away from it.
Term
Medial
Definition
Toward the neuraxis, away from the side of the body.
Term
Ipsilateral
Definition
Located on the same side of the body.
Term
Contralateral
Definition
Located on the opposite side of the body.
Term
Basal Ganglia & Cerebellum Movement Modulation
Definition
Assist with the appropriate planning, initiation, coordination, guidance, and termination of voluntary movements; receive massive cortical input, have one main processing station and intermediate relay, and ultimately send information to the thalamus.
Term
Thalamus Movement Modulation
Definition
Relays information recieved from the basal ganglia & cerebellum back to the motor and premotor areas of the cortex to influence the cortical control of voluntary movement.
Term
Basal Ganglia
Definition
Part of the brain which plays a role in the planning, initiation, and terminations of movements, particularly those with a complex cognitive dimension.
Term
Cerebellum
Definition
Important for the smooth execution and appropriate completion of ongoing movements, particularly those guided by vision.
Term
Damage to the cerebellum
Definition
People with this type of brain damage have trouble with any sequence of rapid movements that require accurate aim and timing (tapping rhythm, pointing at moving objects, etc.).
Term
Caudate nucleus
Definition
A telencephalic nucleus; one of the two input nuclei of the basal ganglia along with the putamen; involved with control of voluntary movement.
Term
Globus pallidus
Definition
A telencephalic nucleus; the primary output nucleus of the basal ganglia; involved with control of voluntary movement.
Term
Putamen
Definition
A telencephalic nucleus; one of the two input nuclei of the basal ganglia along with the caudate nucleus; involved with control of voluntary movement.
Term
Substantia nigra
Definition
A darkly stained region of the tegmentum that contains neurons which communicate with the caudate nucleus and putamen in the basal ganglia.
Term
Cerebral cortex
Definition
Layer of brain tissue composed of neurons that form the surface of the brain; contains many folds.
Term
Deep cerebellar nuclei
Definition
Nuclei located within the cerebellar hemispheres; receive projections from the cerebellar cortex and send projections out of the cerebellum to other parts of the brain.
Term
Cerebellar peduncle
Definition
One of three bundles of axons that attach each cerebellar hemisphere to the dorsal pons.
Term
Parkinson’s Disease
Definition
Disease which arrises from the degenaration of the terminals in the caudate nucleus and putamen which are the projections of dopaminergic cell bodies in the substantia nigra.
Term
Main symptoms of Parkinson’s Disease
Definition
Slow movements, difficulty initiating movements, rigidity of the muscles, resting tremors, postural instability and sometimes intellectual impairment and depressed mood.
Term
Possible causes of Parkinson’s Disease
Definition
Hereditary tendency for lower dopamine; brain converts MPTP to MPP+.
Term
Treatment for Parkinson’s Disease
Definition
L-Dopa, destruction of parts of globus pallidus internal (GPi), fetal transplant from aborted human fetuses.
Term
Huntington’s Disease
Definition
Neuronal degeneration in the caudate nucleus and the putamen, especially of GABAergic and acetylcholinergic neurons.
Term
Main symptoms of Huntington’s Disease
Definition
Onset at the age of 30 to 50. Facial twitch later tremors spread to other parts of body, uncontrollable movements, especially jerky limb ones. Also psychological symptoms: depression, memory impairment, anxiety hallucinations, drug abuse etc.
Term
Cause of Huntington’s Disease
Definition
Hereditary controlled by an autosomal dominant gene on chromosome 4 which results in an inability to metabolize glucose and produces nitric oxide.
Term
Somatosenses
Definition
Provide information about what is happening on the surface of our body and inside it.
Term
Cutaneous sense
Definition
One of the somatosenses; includes sensitivity to stimuli that involve the skin.
Term
Kinesthesia
Definition
One of the somatosenses; include stretch receptors in skeletal muscles that report changes in muscle length (direction) to the CNS as well as stretch receptors in tendons that measure the force (magnitude) being exerted by the muscles.
Term
Organic sense
Definition
One of the somatosenses; receptors are located in muscle lining, outer layers of the gastrointestinal system and other internal organs, and in the lining of the abdominal and thoracic cavities. Many of these tissues are sensitive only to stretch, heat/cold, and some chemicals, but do not report sensations when cut burned, or crushed.
Term
Somatosensation pathway of well localized sensations
Definition
Axons which convey fine touch ascend in this order... 1) dorsal columns in white matter of spinal cord 2) nuclei in lower medulla 3) medial lemniscus fiber band 4) ventral posterior nucleus of the thalamus 5) primary somatosensory cortex 6) secondary somatosensory cortex.
Term
Somatosensation pathway of poorly localized sensations
Definition
Axons which convey pain and temperature synapse with other neurons as soon as they enter the spinal cord and then... 1) cross to the other side of the spinal cord 2) ascend through the spinothalamic tract to 3) the ventral nuclei of the thalamus.
Term
Somatosensory cortex
Definition
Region of the cerebral cortex whose primary input is from the somatosensory system; divided into columns each of which correspond to another part of the body and another somatosensory stimulation (i.e. pain, temperature, pressure, etc...)
Term
Pain
Definition
Defined only by withdrawal response or, in humans, by verbal report; function is to alert us to any damage to our body; people devoid of this suffer a higher number of injuries and are unaware of illness until it is too late.
Term
Endogenous opioids
Definition
A class of peptides secreted by the brain that act as opiates and modify pain sensitivity.
Term
Neural circuits
Definition
Neurons never function in isolation; they are organized into ensembles that process specific kinds of information. Although the arrangement of these ensembles vary greatly according to the intended function, some features are characteristic of all such ensembles. The synaptic connections that define an ensemble are typically made in a dense tangle of dendrites, axons terminals, and glial cell processes that together constitute neuropil.
Term
Electrical stimulation
Definition
Doing this to the of the periaqueductal gray matter causes very strong analgesia.
Term
Analgesia
Definition
Loss of physical discomfort that’s induced in response to chronic pain or during activities that are important to survival.
Term
Causes for behavior
Definition
Biological needs for survival of the individual (temperature regulation, food, water); biological needs for survival of the species (sex); other needs (sensory stimulation, love, social interaction, etc).
Term
Evolutionary psychology
Definition
A new branch of psychology that seeks to investigate the potential role of genetic factors in various aspects of human behavior.
Term
B.F. Skinner (description I)
Definition
Founder of behaviorism; claimed that consciousness is neither a definite nor a usable concept; believed people were incapable of responsibility, self-discipline, self-determined morality and even autonomous achievement; claimed people reacted and behaved according to external forces; stated that thought and awareness were nothing more than annoying, meaningless by-products.
Term
Harry Harlow
Definition
Studied social behavior of monkeys; concluded that sex alone does not drive society and that mother love does not enable individual social relations; believed that normal sexual and parental behavior depended on a wide array of affectional ties with peers and family early in life.
Term
Louis Pasteur
Definition
French chemist who founded modern microbiology; discovered microscopic pathogens; “Cleanliness is next to godliness.”
Term
John B. Watson (description I)
Definition
President of the American Psychological Association, ominously warned expectant parents that "when you are tempted to pet your child, remember that mother love is a dangerous instrument."
Term
Regulatory behavior
Definition
Behavior that ensures the survival of the individual (for example, feeding).
Term
Non-regulatory behavior
Definition
Behavior that isn’t needed to ensure the survival of the individual (for example, sexual behavior or seeking love).
Term
Homeostasis
Definition
The process by which the body's substances and characteristics (such as temperature and glucose level) are maintained at their optimal level.
Term
Physiological regulatory system
Definition
This system maintains the constancy of some internal characteristics of an organism.
Term
System variable
Definition
A characteristic variable that is controlled by a regulatory mechanism; for example, temperature in a heating system.
Term
Set point
Definition
The optimal value of the system variable in a regulatory mechanism.
Term
Detector
Definition
In a regulatory process, a mechanism that monitors and signals when the system variable deviates from its set point.
Term
Correctional mechanism
Definition
In a regulatory process, the mechanism that is capable of changing the value of the system variable and restoring it to its set point.
Term
Negative feedback
Definition
A process whereby the effect produced by an action serves to diminish or terminate that action or correctional mechanism; characteristic of regulatory systems.
Term
Hypothalamus
Definition
Group of nuclei of the diencephalon situated beneath the thalamus; controls the hormonal system; helps regulate the autonomic nervous system, anterior and posterior pituitary glands, and species-typical behaviors.
Term
Pineal Gland
Definition
Gland attached to the dorsal tectum which secretes melatonin at night; involved in reproduction, migration, circadian, and seasonal changes having to do with short vs. long days
Term
Parathyroid
Definition
Tiny glands located in the neck which secrete calcetonin as well as a hormone that regulates the level of calcium in the blood.
Term
Parathyroid hormone
Definition
A hormone produced when the level of calcium in the blood gets too low. Disorders of the gland which produces this hormone result in excessive production of the hormone and high levels of calcium in the blood.
Term
Thyroid
Definition
Organ in the neck surrounding the area of the windpipe where the voice box is located; helps regulate growth, metabolism and prenatal brain development; requires iodine for production of hormones thyroxine and Triiodothyronine; secretes calcitonin.
Term
Thymus
Definition
Small organ beneath the breastbone that functions in the development of the immune system; weeds out lymphocytes that react to proteins produced by the body (self-antigens), thus preventing autoimmune disease; large organ during childhood, but shrinks during adolescence.
Term
Adrenal Gland
Definition
Controlled by sympathetic nerve fibers; secretes epinephrine, norepinephrine, cortisol, and aldosterone.
Term
Epinephrine
Definition
A neurotransmitter secreted by the adrenal medulla; mobilizes the body for fight or flight; also called adrenalin.
Term
Norepinephrine
Definition
A neurotransmitter secreted by the adrenal medulla; more concerned with maintaining normal body activity than with preparing the body for emergencies; also known as noradrenalin.
Term
Cortisol
Definition
A hormone of the adrenal cortex that has various metabolic and anti-inflammatory effects in the body.
Term
Aldosterone
Definition
A hormone of the adrenal cortex that causes the absorption and retention of sodium by the kidneys.
Term
Pancreas
Definition
Organ behind the lower part of the stomach that makes enzymes to help the body digest food; contains the Islets of Langerhans which have alpha cells that make glucagon, beta cells that make insulin, and delta cells that make somatostatin.
Term
Glucagon
Definition
A pancreatic hormone that raises the level of glucose in the blood.
Term
Insulin
Definition
A pancreatic hormone that helps the body use glucose for energy.
Term
Somatostatin
Definition
A pancreatic hormone that regulates the secretion of glucagon and insulin.
Term
Ovaries
Definition
The pair of female reproductive organs on either side of the uterus that produce eggs and the hormones estrogen, estradiol, progesterone and small amounts of testosterone.
Term
Estradiol
Definition
Powerful female hormone that occurs naturally in the ovaries; synthesized and used to treat estrogen deficiency and breast cancer.
Term
Testis
Definition
One of the male gonads located in the scrotal sac that are the site of sperm and testosterone production.
Term
Limbic system
Definition
Hypothetical functional system that controls emotional behavior and expression and certain forms of memory; includes the amygdala.
Term
Amygdala (definition I)
Definition
A limbic structure in the very front of the temporal lobe; involved in emotion and specific types of learning and memory.
Term
Prefrontal cortex
Definition
Brain region that provides ability to plan, reason, concentrate, and adjust behavior, (right response for the right circumstances).
Term
Two reasons for eating
Definition
To construct and maintain our own organs; to obtain energy (for nervous system activities, muscular movements and body warmth).
Term
Digestive system pathway
Definition
Mouth —> esophagus —> stomach —> small intestine —> large intestine
Term
Mouth
Definition
Mixes food with saliva, releases the enzyme amylase.
Term
Amylase
Definition
Enzyme released in saliva that helped break down starchy carbohydrates into glucose, maltose and dextrins.
Term
Hydrochloric acid
Definition
Acid produced in stomach that breaks down proteins in food.
Term
Pepsin
Definition
Enzyme produced in stomach that breaks down proteins in food.
Term
Small intestine
Definition
Section of digestive tract between stomach and large intestine which produces pancreatic juice and bile; most of digestion occurs here as nutrients are absorbed from food.
Term
Pancreatic juice
Definition
Fluid secreted into the small intestine by the pancreas; important for breaking down starches, proteins and fats.
Term
Bile
Definition
Fluid by-product of liver which flows to small intestines; important for waste removal and breaking down starches, proteins and fats.
Term
Large intestine
Definition
Lower portion of the digestive tract whose role is the absorption of sodium chloride and water as well as forming and expelling of waste (feces) from the body.
Term
Digestive behaviors
Definition
Because of the delay between ingestion and the replenishment of the depleted stores, these are controlled by satiety mechanisms as well as by detectors that monitor the system variables.
Term
Satiety mechanisms
Definition
These monitor the activity of correctional mechanisms, not the system variables, stopping eating in anticipation of the replenishment that will occur later. (That’s why we stop drinking after a few glasses of water when dehydrated, even before the fluid has reached our cells)
Term
Stomach distention
Definition
Fullness; this conveys satiety signals to the brain via the vagus nerve and to the spinal cord via the splanchnic nerves.
Term
Vagus nerve
Definition
Nerve involved in stomach distention which conveys satiety to the brain through the stretching of stomach walls.
Term
Splanchnic nerve
Definition
Nerve involved in stomach distention which conveys satiety to the spinal cord through the nutrient content of the stomach.
Term
Lateral hypothalamus
Definition
Part of the hypothalamus which produces feelings of hunger; destruction of this part eliminates hunger while stimulation amplifies it.
Term
Ventromedial hypothalamus
Definition
Part of the hypothalamus which produces feelings of satiety; destruction of this part causes obesity while stimulation suppresses the urge to eat.
Term
Amygdala (definition II)
Definition
Taste preferences and taste aversions are aspects of feeding which originate in this organ.
Term
Inferior prefrontal cortex
Definition
Part of the prefrontal cortex that’s connected to the olfactory bulb; when damaged, olfactory input drops and urge to feed decreases.
Term
Organizational effect
Definition
The effect of a hormone on tissue differentiation and development.
Term
Activational effect
Definition
The effect of a hormone that occurs in the fully developed organism; may depend on the organism's prior exposure to the organizational effects of hormones.
Term
Testosterone
Definition
The principal male sex steroid hormone.
Term
Estradiol
Definition
The principal estrogen of many mammals, including humans.
Term
Alpha-fetoprotein
Definition
Produced in the liver and brain of a fetus and excreted into the amniotic fluid; levels tends to increase in the amniotic fluid when a fetus has open neural tube defect or abdominal wall defect.
Term
Medial Preoptic Nucleus/ Area (MPA)
Definition
Area which plays an essential role in male sexual behavior (destruction, stimulation, physiological recordings, c-fos); receives somatosensory information from genitals through connections with reticular formation and medial amygdala.
Term
Sexually dimorphic behavior
Definition
A behavior that has different forms or that occurs with different probabilities or under different circumstances in males and females.
Term
Sexually Dimorphic Nucleus (SDN)
Definition
Area within the MPA first observed in rats which plays a role in male sexual behavior; larger in heterosexual men and smaller in homosexual men and in heterosexual women.
Term
Medial Amygdala
Definition
Area of the amygdala that receives olfactory information; involved in the effects of odors and pheromones on reproductive behavior; sexually dimorphic.
Term
Ventromedial nucleus of the hypothalamus (VMH)
Definition
Large nucleus of the hypothalamus that plays an essential role in female sexual behavior; located near the walls of the third ventricle; connected to PAG.
Term
Periaqueductal gray matter (PAG)
Definition
Region of the midbrain that plays an essential role in various species-typical behaviors, including female sexual behavior; surrounds the cerebral aqueduct.
Term
Congenital adrenal hyperplasia (CAH)
Definition
A condition characterized by hypersecretion of androgens by the adrenal cortex; in females, causes masculinization of the external genitalia.
Term
Circadian rhythm
Definition
A daily rhythmical change in behavior or physiological process.
Term
Androgen insensitivity
Definition
Causes feminization/ undermasculinization of the external genitalia at birth, abnormal secondary sexual development in puberty, and infertility.
Term
Suprachiasmatic nucleus
Definition
A nucleus situated atop the optic chiasm that contains a biological clock responsible for organizing many of the body's circadian rhythms; larger in homosexual men; smaller in heterosexual men and women.
Term
Anterior Commissure
Definition
A thin white fiber bundle between the olfactory areas of each hemisphere; larger in homosexual men and in heterosexual women and smaller in heterosexual men.
Term
Emotions
Definition
A strong surge of feeling marked by an impulse to outward expression and often accompanied by complex bodily reactions; any strong feeling, as love, hate, or joy; the power of feeling; sensibility.
Term
Emotional Response
Definition
Consists of three types of components: behavioral, autonomic, and hormonal.
Term
Behavioral emotional response
Definition
This emotional response controlls posture, sounds, facial expression, exposure of teeth, etc.
Term
Autonomic emotional response
Definition
This emotional response controlls activation of sympathetic nervous system (e.g. increased heart rate) and inhibition of the parasympathetic nervous system (e.g. less blood to GI tract)
Term
Hormonal emotional response
Definition
This emotional response controlls secretion of epinephrine and norepinephrine from the adrenal medulla which facilitate the effects of the autonomic nervous system; controlls secretion of steroid hormones that will further facilitate the utilization of glucose.
Term
Amygdala (definition III)
Definition
As different circuits are involved in the behavioral, autonomic, and hormonal changes associated with emotions, this organ integrates the different aspects of fear, anger and frusteration.
Term
Stimulation of amygdala
Definition
During this type of treatment, patients report feeling afraid.
Term
Lesions of amygdala
Definition
During this type of treatment, patients emotional responses decrease.
Term
Conditioned Emotional Response (CER)
Definition
A classically conditioned response that occurs when a neutral stimulus is followed by an aversive stimulus; usually includes autonomic, behavioral, and endocrine components such as changes in heart rate, freezing, and secretion of stress-related hormones; not an emotional response.
Term
Charles Whitman
Definition
In 1966, this man climbed a tower at the University of Texas and began to indiscriminantly kill people with a rifle; post-mortem autopsy of his brain revealed a large tumor which extended into the temporal lobe and compressed the amygdala.
Term
Orbitofrontal cortex (definition I)
Definition
Located at the base of the frontal lobes just above the eye sockets; receives direct information from the dorsomedial nucleus of the thalamus, temporal cortex, ventral tegmental area, olfactory system and amygdala; sends information to the cingulate cortex, hippocampal formation, temporal cortex, lateral hypothalamus, and amygdala; also communicates with other parts of the frontal cortex.
Term
Orbitofrontal cortex (definition II)
Definition
Damage to this area reduces people’s inhibitions and self-concern, makes them indifferent to the consequences of their actions, increases their sensitivity to noxious stimuli, and lowers the producuction of emotional reactions to pain.
Term
Phineas Gage
Definition
In the mid-1800s this dynamite worker used a steel rod to ram a charge of dynamite into a hole drilled in solid rock; the charge exploded and sent the rod into his cheek, through his brain, and out the top of his brain; he survived but his personality changed; he became fitful, irreverant, obstinate and impulsive, while possessing the intellectual capacity and manifestations of a child and the animal passions of a strong man.
Term
Brickner, patient A
Definition
In the 1930’s, this man developed a brain tumor in both frontal lobes which had to be cut out. Before the tumor he was disiplined and reserved. After the surgery he became relaxed, boastful, socially uninhibited, and no longer concerned with his profession or future planning. However, his fundamental intellectual ability appeared to be intact, not to mention his perfectly preserved motor, perceptual and language ability.
Term
Jacobson, Wolf & Jackson
Definition
These psychiatrists along with surgeon Egas Moniz worked together to bilaterally ablate the prefrontal cortex of a two chimpanzees. The animals, "Becky" and "Lucy," had been trained to perform a delayed response task. Becky, in particular, displayed a violent temper when she could not remember which of two cups contained food. Following lobotomy, "Becky" made repeated errors without evidence of any emotional response. "Lucy" also showed no loss of intellectual abilities as a result of the frontal lobe lesion.
Term
Egas Moniz
Definition
Surgeon who performed a bilaterally lobotomy on the chimpanzee “Lucy” and later went on to perform the first lobotomy on a human female in order to treat mental illness.
Term
Ice pick procedure
Definition
Type of cheap bilateral prefrontal lobotomy invented by Walter Freeman. An ice pick is inserted through the upper eyelid, pushed past the orbital bone, and finally swept back and forth; used in the 1940’s and 50’s on over 100,000 people with psychiatric disturbances.
Term
Greenblatt and Solomon
Definition
These two psychiatrists defined the four major outcomes of total bilateral frontal lobotomy in 1966: decreased drive, decreased self-concern, depression of outwardly directed behavior and social sense, and shallower affective life.
Term
Stress
Definition
Constraining force or influence as a force exerted when one body or body part presses on, pulls on, pushes against, or tends to compress or twist another body or body part; the deformation caused in a body by such a force; a physical, chemical, or emotional factor that causes bodily or mental tension and may be a factor in disease causation; a state of bodily or mental tension resulting from factors that tend to alter an existent equilibrium.
Term
Stressor
Definition
A stimulus or situation that produces a stress response.
Term
Types of Stress
Definition
1) acute physical stress 2) chronic physical stress 3) psychological and social stressors
Term
Acute physical stress
Definition
One of the three types of stress; includes a lion’s need to hunt.
Term
Chronic physical stress
Definition
One of the three types of stress; includes dought, famine, parasites, etc...
Term
Psychological and social stressors
Definition
One of the three types of stress; includes losing a parking spot, conflicts with a family member, worries about grades, grants, popularity, etc...
Term
Walter Cannon
Definition
Physiologist in the 1920’s who introduced the term stress to refer to the physiological reaction caused by the perception of aversive or threatening situations.
Term
Seyle
Definition
Father of stress physiology; in the 1930’s he formalized the concept of stress physiology with two ideas: general adaptation syndrome and the ability of stressors to make you sick; injected rats with unknown extract from the ovaries of peptic ulcers. This greatly enlarged the rats’ adrenal glands and shrunk their immune tissue.
Term
Stress response
Definition
A physiological reaction caused by the perception of aversive or threatening situations; autonomic and endocrine components of this response act to mobilize the body’s energy resources.
Term