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Principles III-EXAM4-Hearts II 32-37
Heart II
11
Nursing
Graduate
05/02/2010

Additional Nursing Flashcards

 


 

Cards

Term

 

 

What is the treatment for mild hemorrhage associated w/ Warfarin?

Definition

 

 

Vitamin K 1-5 mg IV (1mg/min) or 10-20 mg PO

bleeding is reversed in 4-24 hrs

Term

 

 

What is the treatment for severe bleeding associated w/ Warfarin?

Definition

 

 

FFP, recombinant factor VIIa, prothrombin complex

Term

 

 

What do antifibrinolytics do?

Name two.

Definition

 

 

They reversibly bind w/ plasminogen preventing its conversion to plasmin and the breakdown of fibrin (reduces bleeding)

Trasylol & Amicar

Term

 

 

Aprotonin (Trasylol) does what? When is it frequently used?

Definition

 

Its a broad spectrum protease inhibitor, that inhibits the formation of plasmin that leads to clot formation and an increase in vWBF binding.

 

Its frequently used in re-do hearts

Term

 

 

What is the test dose for Tralysol? Whats a problem w/ it?

Definition

 

 

Test dose is 1 ml (10,000 KIU) over 10 mins prior to loading dose.

 

A problem associated w/ it is, risk for anaphylactic or anaphylactoid reactions

Term

 

 

Whats the "full hammersmith" dose of Aprotinin (Tralysol)?

Definition

 

 

2,000,000 KIU IV over 20-30 min and 2,000,000 KIU in priming solution of pump 

IV drip of 500,000 KIU for length of case until chest is closed

Term

 

 

Whats the elmination half life of Tralysol & how's it eliminated?

Definition

 

 

1.5-2 hrs

eliminated in the kidneys

Term

 

 

Whats the dose of Amicar? How's it given?

Definition

 

 

IV dose 4-5 grams over 1 hour followed by a drip of 1 gm per hour

HEART ROOM: 100 mg/kg over 10 min

 

it can be PO or IV

Term

 

 

When can Amicar be used? When can it NOT?

Definition

 

 

Besides hearts, for bleeding hemophiliacs who have undergone tooth extractions, nose bleeds, severe hematuria, abruptio placenta, and trauma.

 

NOT in active intravascular clotting processes such as DIC

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