Shared Flashcard Set

Details

Pituitary Disorders
VM 610 Midterm
20
Veterinary Medicine
Professional
10/22/2012

Additional Veterinary Medicine Flashcards

 


 

Cards

Term
Feline Acromegaly Signalment
Definition
male cats
mixed breed
mean age 10 years
Term
Feline Acromegaly Effects
Definition
due to effects of growth hormone
increased protein synthesis
decreased protein catabolism
release of fatty acids
decresed carbohydrate utilization
impaired glucose uptake/transport
Term
Feline Acromegaly Clinical Findings
Definition
PU/PD
insulin resistance
Polyphagia
Organomegaly
Prognathia
heart murmur
large head
macroglossia
CNS signs
Term
Feline Acromegaly Lab Findings
Definition
hyperglycemi/glucosuria
protienuria
hyperproteinemia
azotemia
hypercholesterolemia
erythrocytosis
increased ALT
ketonuria
increased ALP
Term
Feline Acromegaly Radiographic Findings
Definition
hepatomegaly
cardiomegaly
renomegaly
spondylosis
arthropathy
Term
Feline Acromegaly Diagnostics
Definition
UA, CBC, Chemistry
Rads
US
T4
Adrenal function testing
Stomatomedin C is most reliable test
Glucose suppression test
CT Scan or MRI of pituitary gland
Term
Feline Acromegaly Treatment
Definition
radiation
surgery
medical therapy for secondary problems
bromocriptine
octerotide
Term
Canine Acromegaly
Definition
caused by progesterone therapy or endogenous progesterone
progesterone stimulates GH secretion from ductular epithelium of the mammary gland
treatment is by ovariohysterectomy or withdrawal of progesterone therapy
Term
Hypopituitaryism
Definition
congenitl in dogs
failure of pituitary development
TSH deficiency
ACTH deficiency
GH deficiency
Term
Pituitary Dwarfism Signalment
Definition
most common in German Shepherd
short in stature
have puppy coats
Term
Pituitary Dwarfism Signs
Definition
growth retardation
failure of dental eruption
delayed growth plate closure
lack of intelligence
soft, cotton-like coat texture
signs of hypoadrenocorticism, hypothyroidism
Term
Pituitary Dwarfism Diagnostics
Definition
urinalysis
CBC
Chemistry
Bile Acids
Abdominal imaging
arterial blood gases
TLI
endocrine testing
measurement of GH is difficult because secretion is episodic
GH stimulation testing
insuline like growth factor 1 assay
measure thryoid, TSH, and ACTH stim test
Term
Pituitary Dwarfism Treatment
Definition
no canine GH available
porcine and human GH has been used
dogs can develop antibodies to GH
diagnosis is usually too late for treatment to be sucessful
thyroid hormone replacement
glucocorticoid and mineralocorticoid replacement
Term
Central Diabetes Insipidus
Definition
lack of AVP production/secretion
may be partial or complete
any disturbance of hypothalamus/pituitary is a potential cause
Term
Vasopressin
Definition
aka antidiuretic hormone
aka arginine vasopressin
synthesized and secreted by neurohypophysis
includes nuclei in hypothalamus which terminate in pituitary
Term
Control of ADH Secretion
Definition
very small reduction is plasma osmolality causes ADH secretion due to CNS osmoreceptor effect
larger drop in ECF volume causes similar amount of ADH secretion due to baroreceptor effect, angiotensin-aldosterone system
ADH secretion stimualated by pain, nausea, vomiting, anesthesia, some drugs
ADH secretion inhibited by alcohol and drugs
Term
Central Diabetes Insipidus Signalment
Definition
dogs/cats
congenital <1 year
acquired at any age
Term
Central Diabetes Insipidus Diagnostics
Definition
don't do a test unless you rule out renal failure and other causes of PU/PD
urinalysis, urine must be dilute
normal CBC
normal chemistry
negative urine culture
normal urinary system, normal adrenal glands, normal liver in ultrasound
Term
Central Diabetes Insipidus Clinical Signs
Definition
PU/PD
Incontinence sometimes
Term
Central Diabetes Insipidus Treatment
Definition
DDAVP
eye drops with DDAVP or oral
treatment is not always required if the owners can deal with the PU/PD
make sure water is always available
monitor for dehydration
monitor for urinary tract infection
Supporting users have an ad free experience!