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Pharmacology-LWIT
Unit 1
67
Nursing
01/21/2012

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Term
What is Pharmacology?
Definition
The study of drugs and their action on the living body.
Term
What is the use of drugs?
Definition
To restore and maintain the healthy functioning of body tissues, organs, and systems and in diagnostic procedures.
Term
Name drug sources.
Definition
ANIMALS: cortisone, insulin.
PLANTS: purple foxglove(lanoxin),white poppy seeds(morphine), kelp(seaweed), penicillin(mold), bark,flower and seeds.
Term
More drug sources.
Definition
VITAMINS MINERALS:K(potassium),Ca(calcium),Iron
SYNTHETIC(ARTIFICIAL) SOURCE- less expensive and more pure( less side effects, less adverse reaction.
Term
Nurse's role
Definition
Knowledge of:
Drug action
Therapeutic effect
Possible adverse effects
Patient teaching.
Term
Therapeutic dose?
Definition
Usual dose for most clients.
Term
Nursing Process ADPIE
Definition
ASSESSMENTS of the patient's needs
DIAGNOSIS of human response needs that nurses can deal with
PLANING of patient's care
IMPLEMENTATION of care
EVALUATION of the success of the implemented care
Term
Objective Data
Definition
It is measurable: weight,skin color, Vital signs.
Includes- Physical assessment,Diagnostic test( PT/INR clotting studies coumadin; PTT- heparin
Term
Subjective Data
Definition
It is "patient states. Allergy history, Complaints
Term
Planning is?
Definition
Sorting and analyzing the data to develop the plan of care and goals.
Term
Implementation is?
Definition
Preparing and administering drugs.
Term
Evaluation is?
Definition
How the patient is responding to the intervention.
Term
Patient teaching ?
Definition
One of out most important roles.
Provide written material,reinforce key points,document.
Term
Drug legislation
Definition
1906 Federal, Food, Drug and Cosmetic Act. Began federal regulation.
Term
USP?
Definition
United States Pharmacopia- National standard for drugs.
Term
First narcotic control?
Definition
1914 Harrison Narcotic Act(morphine)
Term
FDA
Definition
Food and Drug Administration is a federal agency to enforce federal drug laws including: purity,labeling,testing,dispensing, safety, advertising.
Term
1970 Control Substance Act
Definition
Strict control on manufacture and distribution of habit-forming drugs.
Established FIVE schedules of addicting drugs
Term
Schedule one drugs
Definition
Marijuana,Heroin
Term
Schedule two
Definition
Cocaine,Opium, Methadone, Morphine, Oxycodon.
Term
Schedule three
Definition
Anabolic steroid.
Term
Schedule four
Definition
Benzodiazepines.
Term
Schedule five
Definition
Pregabalin
Term
Drug names
Definition
Generic name(lower case)
Trade/Brand name(upper case)
Term
Generic name drug?
Definition
Is named after the chemical name of the active ingredient.
Term
Brand/Trade name/
Definition
Is given by the manufacturer who developed the drug.
Term
Differences between generic and brand name drugs.
Definition
First is the price, Second the quality of the binders used to hold the active ingredients.
Term
USP/NF(FDA)
Definition
It limits how much a facilities can carry.
Term
Pharmacokinetics is ?
Definition
The use of the drugs by the body.
Term
What are the 4 phases of pharmacokinetics?
Definition
Absorption
Distribution
Biotransformation
Excretion
Term
Absorption is?
Definition
Passage of drug from site of entry to bloodstream.
Term
What factors affect absorption?
Definition
Route of administration
The condition of the site(fat tissue in abdomen)
Drug form, Timing
Gastric emptying
Term
Distribution is?
Definition
Progress or transportation from bloodstream to particular site of action(receptor cell).
Term
What factors affect distribution?
Definition
Circulation
Cardiac output,
Blood supply
Level of albumen(plasma protein)
Term
Target tissue is?
Definition
The place where the drug bonds chemically.
Term
Biotransformation(metabolism)
Definition
Process by which the drug is detoxified.
Breakdown of drug for excretion.
Term
What factors affect biotransformation?
Definition
Liver condition
"First Pass" through the liver is why the oral drugs have higher dosage.
Term
Excretion is?
Definition
Elimination of the drug from the body.
Term
What factors affect excretion?
Definition
Condition of the kidney
Perspiration
Term
Local
Definition
Affects only area where the drug is placed, like eye drop.
Term
Systematic
Definition
Affects the entire body because the drug is absorbed in the blood stream.
Term
Therapeutic effects
Definition
Medical treatment of any kind, the results of which are judged to be desirable and beneficial.
Term
What is a dose?
Definition
A single administration of drug given at one time.
Term
Drug interaction?
Definition
When one drug alters the action of another.
Term
Agonist?
Definition
A drug that produces a predictable response at the intended site of action.
Term
Antagonist?
Definition
A drug that blocks the action of another drug.
Term
Additive?
Definition
Drugs of similar action.
Term
Synergistic/Potentiating
Definition
Two drugs with different reaction produce greater effect.
(demerol+ fenergen=3times stronger)
Term
Half life?
Definition
The amount of time for serum concentration to be absorbed by 50%.(heparin)
Term
NARCAN
Definition
Cancels the effects of cocaine ,heroin
Term
Gentamycin
Definition
Real strong antibiotic with side affect of possible permanent hearing loss.
Term
Incompatibility
Definition
Drugs that do not combine with other drugs.
Term
Idiosyncratic
Definition
Unusual and unexpected highly individual reaction.
Term
Anaphalctic(Allergic)
Definition
Hypersensitiveness. It can be severe and life threatening.
Term
Cumulative
Definition
When drugs build up in the body due to higher dose; poor circulation; poor metabolism; excretion.
Term
Adverse/Side effect
Definition
Undesirable action
Term
Minimal dose
Definition
Smallest amount necessary to give the therapeutic effect.
Term
Loading dose
Definition
Initial dose is larger than continuing dose

Term
Maximal dose
Definition
Is the largest amount that can be given safely.
Term
Toxic dose
Definition
With poisoning or over dose or toxicity
Term
Lethal death
Definition
Causing death
Term
Who can write prescription?
Definition
MD,DO(doctor of osteopathy), ARNP,PA,DVM(veterinarian)
Term
Written orders
Definition
Common and safest.
Term
Verbal orders
Definition
VO(verbal orders), TO(telephone orders).
Term
Standing orders
Definition
Sliding scale insulin( hold if more than 110)
Term
Stat order
Definition
Immediately.
Term
Parts of prescription
Definition
Patient's name, Date-Time,Name of drug,Dose of drug,Time-Frequency, Method-Route, Health care provider signature.