Shared Flashcard Set

Details

Pharm 29
Pharm 29
18
Pharmacology
Undergraduate 2
08/17/2011

Additional Pharmacology Flashcards

 


 

Cards

Term

Which statement will indicate that the patient understands the discharge instructions regarding cholestyramine (QUESTRAN)

 

 

I will increase fiber in my diet

 

Cholestyramine can cause constipation; thus increasing diet is appropriate.

Definition
Term

The nurse plans which of the following interventions to decrease the flushing reaction of niacin

 

 

Administer ASA 30 mins. before nicotinic acid

 

Administration of an antiflammatory drug such as ASA has been seen to decrease the flusing reaction associate with niacin

Definition
Term

HMG-CoA inhibitors (STATINS) are generally administered at which time

 

In the evening

 

The liver produces the majority of cholesterol during the night.  Thus statin drugs, which work to decrease this synthesis, are generally administered during the evening so that blood levels are highest

Definition
Term

Which are common side effects of fenofibrate (TRICOR) a fibric acid derivative

 

Nausea, Vomitting, and Adbdominal Pain

Increase in gallstone formation

Impotence

 

Diarrhea, not constipation is a common side effect of fibric acid derivatives

Definition
Term

Discharge teaching for a patient receiving an antilipemic medication would include

 

Continue your exercise program, and maintain a diet high in omega-3 fatty acids

 

The therapeutic regimen used to decrease serum cholesterol

Definition
Term

What is the mechanism of action of ezetimibe (ZETIA)

 

Inhibiting absorption of dietary and biliary cholesterol in the small intestine

 

Ezetimibe is the newest type of antilipemic medication, working by inhibiting the absorption of cholesterol in the small intestine

Definition
Term

Cholestyramine (QUESTRAN) decreases lipid levels by

 

Binding to bile in the intestional tract, forming an insoluble complex that is excreted in the feces.

 

Cholestyramine is an anion exchange resin that binds to bile to form an insoluble complex that is excreted.  The liver must then use cholesterol to synthesize more bile.

Definition
Term

Which statement made by the patient demonstrates knowledge deficit regarding colestipol (COLESTID)

 

I should mix and stir the powder in as small amount offluid as possible in order to maintain potency of medication.

 

Colestipol is a powder that must be well diluted in fluids before administration to avoid esophageal irritation or obstruction.

Definition
Term

Atrivastation (LIPITOR) decreases lipid levels by

 

Inhibiting HMG-CoA reductase, the enzyme responsible for the biosynthesis of cholesterol in the liver

 

Atorvastatin (LIPITOR) is an HMG-CoA inhibitor, decreasing the sythesis of cholesterol in the liver

Definition
Term

Which test will the nurse use to assess for adverse reactions to HMG-CoA reductase inhibitors

 

Liver Function Tests

 

HMG-CoA reductase inhibitors can cause hepatic toxicity thus it is necessary to monitor liver function tests every 3 months for the first year

Definition
Term

Discharge teaching for a patient receiving simvastatin (ZOCOR) should include the importance of reporting which symptoms that might indicate a serious adverse reaction to the medications

 

Muscle pain

 

Muescle pain must be reported because it could signfy an uncommon but serious side effect of rhabdomyolysis associated with statin drugs

Definition
Term

The nurse would question an order for simvastatin (ZOCOR) in a patient with which condition

 

Hepatic DX.

 

Simvastatin (ZOCOR) can cause an increase in liver enzymes and thus should not be used in patients with preexisiting liver dx.

Definition
Term

A patient with elevated triglyceride levels unresponsive to HMG-CoA reductase inhibitors will most likely be prescibed which drug

 

gemfibrozil (LOPID)

 

Gemfibrozil, a fibric acid derivative promotes catabolism of triglyceride-rich lipoproteins

Definition
Term

The nurse would question an order for colesvelam (WELCHOL) in a patient with which condition

 

Complete Bowel Obstruction

 

Coleseval (WELCHOL) binds with bile in the intestinal tract to form an insoluble complex.  It can also bind to other substances and lead to intestinal obstruction

Definition
Term

The nurse will assess a patient receiving gemfibrozil (LOPID) and warfarin (COUMADIN) for which adverse effect

 

Increased risk of bleeding

 

Gemfibrozil can bind with vitamin K in the intestinal tract, vitamin K absorption

Definition
Supporting users have an ad free experience!