*relax muscle spasms

*prevent and treat malignant hyperthermia

*inhibit release of calcium

*blocks muscle contraction

*muscle weakness

*drowsy, dizzy

*diarrhea

*liver toxicity (w/ higher doses and long term)

*monitor for: diarrhea, drowsiness, muscle strength, liver function tests

*start oral doses low and ↑ slow

*oral: given 1-2 days preop

*IV

*Report: weakness, prolonged diarrhea

*Avoid: driving, CNS depressants (ETOH)

*Potential liver damage

* ♥ disease

* lung disease

*neuromuscular disorders

*pts older than 35yo

*estrogen ↑ risk of liver toxicity

*CNS depressants (ETOH) ↑ risk of severe sedations

*IV use: calcium channel blockers ↑ risk of severe dysrhythmias