Details

Title: Peds path: congenital defects

Description: definitions

Total Flash Cards: 6

Created: 10/01/2009 07:17:19

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Additional Pathology Flashcards

Cards in this set:

Term
Malformation
 Definition
Morphologic defect of an organ, part of an organ, or larger region of the body resulting from INTRINSICALLY abnormal developmental process (w/in a developmental field). Ex: anencephaly
Term
Disruption
 Definition
Morphologic defect resulting from EXTRINSIC breakdown of, or interference w/, normal development. Usually sporadic. Ex: ADAM complex.
Term
Deformation
 Definition
Abnormal form, shape, or position of a part of the body caused by mechanical forces. In- or extrinsic! Ex: flexion deformities.
Term
Sequence
 Definition
Pattern of multiple defects derived from a single anomaly. Pathogenesis- uniform. Phenotype- characteristic. Etiology- variable. Ex: Oligohydramnios sequence.
Term
Syndrome
 Definition
A recognized pattern of multiple anomalies known or thought to be pathogenetically related & not a know sequence. Ex: trisomies
Term
Association
 Definition
A non-random occurrence in 2 or more individuals of multiple anomalies & not a sequence or syndrome. Ex: VACTERL Assoc.