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Pathphysiology Water Imbalance
Water Imbalance: Iso-,Hyper-, and Hypo- and other electrolyte imbalances clinical manifestations
24
Pathology
Undergraduate 3
02/22/2010

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Term
Isotonic Fluid Volume Loss/Deficit
Definition
decrease BP, wt. loss, poor skin turgor, tachycardia, decreased urinary output
Term
Isotonic Fluid Volume Gain/Excess clinical manifestations
Definition
^BP,wt. gain, edema, ^Urinary output, Signs and symptoms of circulatory overload like jugular vein distention
Term
Isotonic Imbalances def.
Definition
Cells do not cause shrinkage or swelling b/c ECF +/- = Na +/-
Term
Hypertonic fluid imbalances def.
Definition
Excess of Na+ in blood RELATIVE to fluid portion of blood
Term
Hypertonic Fluid Imbalances: water (loss,gain) or solute(loss, gain) and cells(shrink, swell)
Definition
water loss, solute gain, cell shrinks
Term
Hypernatremia def.
Definition
^ in solute in ECF
Term
Hypernatremia Clinical Manifestations
Definition
Brain cell shrinking,leads to muscle weakness and twitching, seizures
Term
Intracellular dehydration signs
Definition
Thirst, fever, decr. UOP
Term
Water deficit(Hypovolemia)def.
Definition
^Na in relation to water
Term
Hypovolemia clinical manifestations
Definition
Wt. loss, weak pulse, postural(orthostatic) hypotension, tachycardia, thirst, fever, UOP, dehydration signs
Term
Hypotonic Fluid Imbalances def.
Definition
Deficit of Na in blood as compared to fluid portion of blood
Term
Hypotonic fluid imbalance: water(gain, loss), (^,decr.) serum osmolarity, (more,less) concentrated ECF and (more,less) concentrated ICF, and cells (swell, shrink)
Definition
water gain, decr. serum osmolarity, less conc. EFC, more conc. ICF, cells swell
Term
Hyponatremia def.
Definition
decr. solute in ECF
Term
Hyponatremia clinical manifest.
Definition
Brain cell swelling, depression, confusion, coma, headache, termors, seizures, edema, wt. gain
Term
Hypervolemia def.
Definition
water excess, increase in fluid relative to solute(Na)
Term
Hypervolemia clinical manif.
Definition
pulmonary & cerebral edema, muscle twitching, wt. gain, peripheral edema, polyuria
Term
Another word for hypervolemia
Definition
Dilutional hyponatremia, water excess
Term
Function of Sodium
Definition
Major ECF cation, water balance, nerve impulse,acid base balance, blood pressure
Term
Function of Potassium
Definition
Major ICF cation, maintains resting membrane potential of muscle & nerve cells, heart rhythm and muscle contraction
Term
Hyperkalemia(>5.0 mEq/L) Early, late clinical manifestations
Definition
Early: Hyperactive muscles
Later: weakness, paralysis
General: Tingling, numbness, anxiety
decr. conductivity-->dysrhythmias/cardiac arrest, nausea, diarrhea, oliguria, metabolic acidosis
Term
Hypokalemia(<3.5mEq/L) clinical manifestations
Definition
muscle weakness, paralysis, resp. arrest, cardiac irritability(dysrhythmias/cardiac arrest), thirst, nausea and constipation, parestheisas, polyuria, metabolic alkalosis
Term
Function of Calcium
Definition
need for bones, teeth, cell membrane permeability, blood clotting, nerve impulse transmission, muscle contraction
Term
Hypercalcemia(>10.5 mg/dL)clinical manifestations
Definition
decr. neuro. excitability--->muscle weakness, constipation, CNS depression, bone pain, osteoporosis, pathologic fractures, kidney stones, hyperparathyroidism
Term
Hypocalcemia (<8.8 mg/dl) clinical manifestations
Definition
^neuro. excitability, twitching/convulsions, laryngospasms, muscle cramps, tetany, bradycardia/cardiac arrest, hypoparathyroidism, chronic renal failure
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