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Pathology Unit V
Female Reproductive Tract: Vagina
12
Pathology
Graduate
03/06/2013

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Cards

Term
general incidence of primary carcinoma of the vagina
Definition
extremely rare, often involved secondarily by cancer or infections arising in adjacent organs
Term
adenosis definition
Definition
Adenosis is the presence of glandular epithelium in the vaginal wall (which is normally lined by nonkeratinizing stratified squamous epithelium).
Term
putative causative agent of adenosis
Definition
developmental abnormality observed in female children who were exposed to diethylstilbestrol (DES) in-utero.
Term
and explain the relationship of adenosis to carcinoma of the vagina
Definition
metaplasia, can lead to clear cell carcinoma
Term
incidence of clear cell carcinoma of the vagina
Definition
very rare tumor (except upon exposure to DES)
Term
clinical course of clear cell carcinoma of the vagina
Definition
: exposure leads to small glandular or microcystic inclusions that appear on vaginal mucosa. Red granular-appearing foci lined by mucus secreting cells = adenosis --> clear cell carcinoma
Term
incidence of squamous carcinoma of the vagina
Definition
extremely rare, 60 years old +,
Term
clinical symptoms of squamous carcinoma of the vagina
Definition
Usually well-differentiated, associated with HPV infection
Term
most common anatomic sites involved in squamous carcinoma of the vagina
Definition
Term
incidence of sarcoma botryoides
Definition
embryonal rhabdomyosarcoma of the vagina of infants and children under age 5.
Term
gross features of sarcoma botryoides
Definition
the tumor protrudes like a bunch of grapes from the vagina
Term
clinical course of sarcoma botryoides
Definition
can also occur in urinary bladder or bile ducts
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