Shared Flashcard Set

Details

Pathology Exam 1 lecture 4
Immune system
25
Pathology
Graduate
07/11/2016

Additional Pathology Flashcards

 


 

Cards

Term
innate immunity
Definition
-body's first line of defense
-does not differentiate between different types of invaders
-non-adaptive
Term
acquired immunity
Definition
system has memory of organisms encountered so as to react more effectively to future invasion
Term
antigen
Definition
foreign substance
Term
antibody
Definition
identifies foreign substances and tags them
Term
types of acquired immunity
Definition
HUmoral (B) - free floating
Cell mediated (T) - in cells
Term
corticosteroids
Definition
treat immune-mediated disorders
anti-inflammatory and immunosuppressive
Term
Cyclosporine
Definition
immunosuppressive
selective suppression of helper T cells
Term
Radiation therapy
Definition
cytotoxic to lymphocytes, causes lymphopenia, resulting in immunosuppression
Term
Exercise on immunology
Definition
moderate - beneficial
strenuous - immunosuppression
Term
AIDS and CD4
symptoms
Definition
CD4 count is below 200 cells/mL
destruction of T helper cells
unable to fight off opportunic infection
neurologic dysfunction
dementia, thin hair & skin, pain
Term
normal CD4 count
Definition
600-1200 cells/mL
Term
Fibromyalgia syndrome
Definition
widespread tissue pain
90% are women
no diagnostic test
Term
FMS signs
Definition
Fibromyalgia
-Pain
-Chronic fatigue
-headaches
-unrefreshed sleep
-tenderness
-concentration or memory problems
Term
FMS treatment
Definition
Benefits
-Pain control
-improved QOL
-Improved sleep
Term
forms of innate immunity
Definition
skin
stomach acid
tears
phagocytes
NK cells
dendritic cells
Term
humoral response
Definition
involving B lymphocytes
recognizes foreign substance and produces antibodies that bind to it and neutralize it
Term
cell-mediated response to bacteria
Definition
involving T lymphocytes
recognizes foreign substances and produces cytokines to help the macrophage lyse and phagocytose
Term
cell mediated response to virus
Definition
involving cytotoxic T lymphocyte
recognizes the cell and destroys it
Term
complement system
Definition
part of innate immunity
recognizes the invading organism and destroys it
Term
exercise on neutrophils and macrophages
Definition
increases with eccentrics
Term
exercise on natural killer cells
Definition
number and function increase during exercise, but decline following
Term
exercise on lymphocytes
Definition
increase during, fall after
Term
exercise on cytokines
Definition
immediate decrease
Term
exercise on infection
Definition
depends on severity, so symptoms should be monitored
Term
life cycle of HIV
Definition
1. flows around body looking for CD4 cells to infect
2. Binds to CD4 and gains entry to the cell
3. infection (viral RNA enters CD4 cell)
4. reverse transcription (copies RNA to look like DNA)
5. integration of new DNA into CD4 nucleus
6. Transcription (CD4 cell is making new HIV)
7. Assembly of the core structure
8. Budding - leaving the cell
9. Breaking free of the CD4 cell
Supporting users have an ad free experience!