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Overview of Immune System
N/A
18
Science
Undergraduate 2
04/13/2012

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Cards

Term
Two major functions of immune system
Definition
1) Destroy pathogens
2) Detect and kill abnormal cells (eg. cancer cells)
Term
Five types of pathogens from largest to smallest
Definition
1) Parasitic worms
2) Fungi
3) Protozoa
4) Bacteria
5) Viruses
Term
What type of pathogen is always intracellular?
Definition
Viruses
Term
What type of pathogen is always extracellular?
Definition
Parasitic worms
Term
When surface barriers are penetrated what is the next line of defense?
Definition
Innate internal defenses
Term
Four key ways adaptive immunity differs to innate immunity?
Definition
1) Specific
2) B & T lymphocytes
3) Memory
4) Systemic
Term
Specific B cells called ________ secrete ________ which bind to antigens?
Definition
Plasma cells, antibodies
Term
Immunity directed against pathogens in extracellular fluid?
Definition
Antibody mediated immunity
Term
Immunity directed against pathogens within cells?
Definition
Cell mediated immunity
Term
Which type of immunity involves antibodies?
Definition
Adaptive
Term
Three circumstances when T cells would be activated against body's cells
Definition
1) Autoimmune disease
2) Viruses
3) Type II hypersensitivity
Term
Innate external defenses
Definition
Surface barriers - skin, mucous membranes
Term
Innate internal defenses
Definition
Cells and chemicals in body fluids - phagocytes, NK cells, fever & inflammation
Term
Adaptive defenses
Definition
Specific
Involves T & B lymphocytes
Memory
Systemic
Term
Humoral (cell mediated immunity)
Definition
Directed against pathogens in extracellular fluid. Involves B lymphocytes and antibodies
Term
Cell mediated immunity
Definition
Directed against pathogens within the cells, involves T lymphocytes
Term
Innate internal defense system
Definition
1) Phagocytic cells
2) Natural killer cells
3) Antimicrobial proteins (complement and interferon)
4) Inflammation
5) Fever
Term
Pyrogens
Definition
Chemicals secreted by leukocytes and macrophages that have been exposed to foreign substances in the body. Cause body's thermostat to set to higher temp
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