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opioids
n/a
16
Pharmacology
Graduate
11/18/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
morphine
Definition

class: strong agonist

 

CNS effects: analgesia, euphoria, sedation, antitussive, respiratory depression(death), miosis, emetic, trucal rigidity

 

Peripheral: constipation

 

Use: pain, pulmonary edema (DING)

Term
heroin
Definition

class: strong agonist

 

enhanced ability to enter CNS

 

VERY ADDICTIVE

(derp)

Term
meperdine
Definition

class: strong agonist

 

atropine like effect

NO MIOSIS

 

do not mix w/ MAOI

Term
methadone
Definition

class: strong agonist

 

longer duration w/ lower kinetic activity

 

used at rehab to get off heroin

Term
fentanyl
Definition

class: strong agonist

 

extremely potent(50x morphine), short duration

 

use- colonoscopy

 

does not cause cardio depression

Term
tramadol
Definition

class: strong agonist

 

used in hospital for pain

 

not a controlled substance

Term
codeine
Definition

class: moderate agonist

 

better bioavailability

 

use- antitussive

 

SIZZURP aka PUPRLE DRANK

Term

oxydocone

 

hydrocodone

Definition

class: moderate agonist

 

use: analgesia

 

drug seekers choice

Term
propoxyphene
Definition

class: weak agonist

 

potency similar to aspirin

 

can mix w/ etOH to die!!

Term
pentazocine
Definition

class: mixed agonist/antagonist

 

orally effecatious

 

moderate pain relief, highly sedative

 

can precipitate withdral in addict

Term

bupenorphine

 

butorphanol

 

nalbuphine

Definition

class: mixed agonist/antagonist

 

given by injection

 

little abuse liability

 

can precipitate withdrawl in addict

Term
naloxone
Definition

class: antagonist

 

given IV, reverse opioid overdose

 

will not cause problem if person turns out ot be not opioid intoxicated

DING- benzo antagonists will cause seizure in a non-benzo intox

Term
naltrexone
Definition

class: antagonist

 

orally effective

 

can precipitate withdrawal

 

can use to curb etOH or opioid cravings

 

liver toxic

 

 

Term
nalmefene
Definition

class: antagonist

 

long-acting insectable

Term

loperamide

 

diphenoxylate

Definition

class: antidiarrheal

 

low abuse potential

Term
dextromethorphan
Definition

class: antitussive

 

use similar to codeine however no CNS activity

 

therefore less abuse potential

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