Term
What subjects are interrelated to pharmacology?
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Definition
Anatomy & physiology, chemistry, pathophysiology
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Term
Give an example of Stage IV testing (post-marketing surveillance).
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Definition
Vioxx, others pulled from market
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Term
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Definition
Dispensing of drugs to patients after examined by licensed HCP.
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Term
Give an example of a bioterrorist threat.
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Definition
Anthrax contamination, incapacitating chemical / radiation exposure
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Term
What is the biggest disadvantage of OTC drugs?
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Definition
SEs unknown by public, wrong drug for problem, not diagnosed “self-diagnosed”
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Term
What is the mechanism of action for a diuretic used to treat hypertension?
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Definition
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Term
What category of scheduled drugs has the lowest abuse potential?
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Definition
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Term
The therapeutic classification focuses on what a drug does clinically. T or F
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Definition
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Term
What drug category is considered the most harmful for the unborn fetus?
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Definition
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Term
All OTC drugs are safe for pregnant women. T or F
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Definition
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Term
How does a sublingual drug work?
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Definition
Enters the blood stream directly
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Term
How could nausea associated with some medications be minimized?
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Definition
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Term
What would happen if one applied a topical medication to dry, cracked skin?
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Definition
Systemic absorption / SEs, irritation
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Term
What would be the most harmful problem that could occur from administration of a local anesthetic (besides anaphylaxis)?
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Definition
Systemic side effects from absorption into the general circulation
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Term
What drug administration method is used to administer Insulin?
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Definition
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Term
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Definition
Drug available to produce a biological response
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Term
What does a longer half-life mean?
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Definition
Stays in the body longer – short t1/2 would be eliminated quicker
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Term
Which pharmacologic phase would MOST affect patients with liver disease?
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Definition
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Term
Why do geriatric patients have altered sensitivity to drug therapy? What other group is affected similarly?
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Definition
Reduced liver enzyme activity
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Term
What is the first-pass effect?
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Definition
Only a portion of the drug dose reaches the target tissue/organ due to liver metabolism of drugs known as the first pass effect.
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