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Neurotransmitters
Behavioral Science
28
Psychology
Graduate
01/08/2013

Additional Psychology Flashcards

 


 

Cards

Term
what is the structure of a monoamine?
Definition
amine group connected to aromatic ring by a 2 carbon chain
Term
Function of glutamic acid decarboxylase (GAD)
Definition
Glutamate-->GABA
Term
Ach PNS receptor
Definition
Nicotinic (depol. ONLY)
Term
Ach CNS receptor
Definition
Muscarinic
Fast IPSP and slow EPSP
Term
Glutamate pyramidal cells of the cerebral cortex
Definition
Basal ganglia, thalamus, spinal cord
Term
GABA in cerebellar cortex (purkinje cells)
Definition
deep cerebellar nuclei
Term
GABA in caudate nucleus and putamen
Definition
globus pallidus and substantia nigra
Term
GABA in globus pallidus and substantia nigra
Definition
thalamus, and subthalmic nuclei
Term
Glutamate NMDA receptor
Definition
NT and voltage gated
free Mg2+ blocks channel allowing Ca flux
Term
GABA A receptor
Definition
ligand gated
benzo and barbs attach here
Term
GABA B
Definition
G protein
EtOH and baclofen
Term
mech of action of tetanus and strychnine
Definition
inhibit presynaptic GABA release
Term
stiff person syndrome
Definition
Ab's to GAD causing autoimmunity
Term
Benzo treatment of seizure
Definition
incr. GABA efficiency
Term
Valproate mech of action
Definition
inhibit enzymes that deactivate GABA
Term
Topiramate mech of action on GABA
Definition
inhibits its re-uptake
Term
Dopamine
Definition
pars compacta and ventral tegmental
Term
nigrostriatal tract of dopa
Definition
smooth muscle action (D2 receptor)
Term
mesolimbic tract of dopa
Definition
fear and reward response

D1 in nucleus accubmens
Term
mesocortical tract of dopa
Definition
motivation and response
Term
tubero-infundibular tract
Definition
regulates prolactin
Term
Parkinson's
Definition
D2 blockade
Term
5-HT
Definition
raphe nucleus
1and2 receptor- mood, appetite, energy, sexual function
3- nausea
Term
norepinephrine
Definition
locus ceruleus
Term
Norep disorders
Definition
Parkinsons- locus ceruleus degeneration

cocaine- inhibits reuptake
panic attacks- reuptake deficiency
Term
Acetylcholine
Definition
nucleus basalis of Mynert(neocortex)/pedunculopontine nucleus(projects to thalamus)
Term
Ach effect
Definition
Peripheral: PS stimul
CNS: inhib or excit
Term
Ach disorders
Definition
Nicotinic- SLUDGE

Muscarinic- Hot as a hare
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