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Neuro
Week 3a - NMJs and ANS (Chirwa)
5
Accounting
Pre-School
03/07/2013

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Cards

Term
What happens to AChe after binding to the cholinergic receptor (nicotinic) at the neuromuscular junction?
Definition
-It is degraded by AChE and sent back to the presynaptic neuron as choline
-There, Ch is reacted with **Acetyl CoA using **choline acetyltransferase to produce ACh one again
-This is then reloaded into vesicles
Term
What does EPP stand for?
Definition
-Endplate potential, may also be written MEPP
(just for reference)
Term
Are there voltage gated Na+ channels at the endplate?
Definition
-No, only metabotropic (nicotinic ones)
Term
What degrades NE and where do we find it?
Definition
-For adrenergic receptors, norepinephrine is used (NE)
-Instead of being degraded outside the neuron, it is taken back up by it via active transport, and degraded by **MAO
Term
What kinds of cholinergic receptors are there on effector organs for autonomics?
Definition
-All muscarinic
-Sympathetic use mainly NE, and ACh for sweat glands
-*Para use all ACh, though
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