Shared Flashcard Set

Details

Neuro disorders
quiz chapter
20
Pathology
Graduate
02/08/2011

Additional Pathology Flashcards

 


 

Cards

Term
 Motor Pathway
Definition

1) UMN call body are in the motor cortex--> send axon down through the internal capsule

2) Through the brain stem from the pyramids on the medulla

3) lower medulla- 80% UMN cross over the midline to form lateral corticospinal tract in the lateral white matter

4) most remaining uncrossed fibers tract down the anterior corticospinal tract in the spinal cord

Term
 Myasthenia Gravis
Definition

Disorder of transmission at the neuromuscular junction that effects communication with motor neuron and muscle cell

 

Autoimmune disease caused by an antibody mediated destruction of acetylcholine receptors in the neuromuscular junction r/t abnormal T-lymphocytes function generally associated with Thymus or Thymic hyperplasia

Term
Curare
Definition

 

Acts on post-synaptic membrane of motor end- plate perventing depolarization

 

Muscle relaxtion

Term
physostigmine/ neostigmine
Definition

Inhibit ACE and cause accumulation of acetylcholine

 

Used in Myasthenia Graves

Term
 Clostridum Botulinum
Definition

 Blocks release of acetylcholine

 

-Paralysis

 

-Used with spasmodic tortillas

Term
 organophosphates
Definition

 Bined ACE to prevent the break down of acetylcholine

 

Excessive and prolonged acetylcholine action with depolarization block of cholirergic receptors

Term
Guillain-Barre' Syndrome
Definition

 Acute immune- mediated polyneuropathy due to immune mechanism with motor sensory or autonomic manifestation

 

Linked with C. jejyni, CMV, EBV, infection

Term
 Parkinson Disease
Definition
 Degenerative disorder of the basal ganglia that results in variable combination of tremor, rigidity and bradykinesia
Term
idiopathic parkinson disease
Definition
dopamine depletion resulting from degeneration of dopamine producing neurons of nigrostriatal pathway
Term

 

 

inherited forms of Parkason

Definition

 

 

mutation of a-synuckin and parkinsons genes

Term

 

 

Additional causes of parkinsons

Definition

 

 

post encephalitic syndrom anti psychotic drugs

Phenothiazines

CVA, tumors, repeated head trauma

Term

 

 

 

Truncal Ataxia

Definition

 

 

inability to maintain a steady posture

Term

 

 

 

Nystagmus

Definition

 

 

Inability of eye to fix on target

Term

 

 

Amyotrophic lacteral sclerosis

(lou Gehrig disease)

Definition

Degeneration and death of LMN in ventral horn

Umn in CC, motor nuceli of brain stem

intellegence and sensory stays

55-60 y/o males

Progressive disease- survival 2-5 years onset symptoms

Term

 

MS

 

Multiple sclerosis

Definition

 

A demyelonating disease of the CNS

 

patho: Demyelination and subsequent degeneration of Nerve fibers in teh CNS resulting in conduction abnormalaties from decreased conduction velocity to conduction blocks

Term

 

 

Anterior Cord Syndrome

Definition

 

 

damage to anterior section of cord

damage to anterior spinal arterior causing infarction of anterior 2/3 of cord

Loss of motor function- damage to cortisospinal tracts

Fine touch and proprioception stays intact

Term

 

 

brown- sequard Syndrome

Definition

 

Damage to one hemisection of the cord motor function loss on same side

 

Pain and temperature sensation lost from contralateral side

Term
Central Cord Syndrome
Definition

Injury to central gray/ white matter- occurs in cervical cord

 

Arms more affected that legs

Term
cauda equina syndrome
Definition
LMN type asymmetric flaccid paralysis with sensory impairment
Supporting users have an ad free experience!