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Nervous System, Nerve Impulse and Spinal Cord
A&P 2 Exam 1 Flashcards
372
Anatomy
07/17/2009

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Term
What are the three main functions of the nervous system?
Definition
1) maintain homeostasis (keep controlled conditions within limits that maintain life)
2) perceptions, behaviors, memories, and all voluntary movement
3) innervate
Term
What are the two divisions of the nervous system?
Definition
Central Nervous System (CNS) and Peripheral Nervous System (PNS)
Term
What does the CNS consist of?
Definition
Brain and Spinal Cord
Term
What is the CNS responsible for?
Definition
Thoughts, emotions and memories.
Term
What is the CNS the origin of?
Definition
Impulses that stimulate muscles to contract and glands to secrete.
Term
What does the PNS consist of?
Definition
All nervous tissue outside of the brain and spinal cord (spinal nerves, cranial nerves, named nerves, ganglia and sensory receptors).
Term
What are the three divisions of the PNS?
Definition
Somatic Nervous System (SNS), Autonomic Nervous System (ANS) and Enteric Nervous System (ENS).
Term
What does the SNS do?
Definition
Brings sensory information from special sensory receptors in the head, body wall and limbs to the CNS and brings voluntary motor commands from the CNS to the skeletal muscle.
Term
What does the ANS do?
Definition
Brings sensory information from the organs (viscera) to the CNS and brings involuntary motor commands from the CNS to the smooth (involuntary) muscle of the organs.
Term
What does the ENS do?
Definition
Its sensory neurons monitor chemical changes within the GI tract and the stretching of its wall via the enteric plexus. Motor neurons govern contraction of the smooth muscle of the GI tract, secretions of the digestive organs, and activity of the endocrine cells (hormone production).
Term
What does the enteric plexus do?
Definition
It allows the sensory neurons to monitor chemical changes in the GI tract and the stretching of its walls.
Term
What is a neuron?
Definition
A single cell responsible for sensing, thinking, remembering, controlling muscle activity and regulating glandular secretions.
Term
What type of neuron is afferent, receives information from stimulus in the PNS and brings it to the CNS?
Definition
Sensory Neurons
Term
Which type of neuron is efferent and carries motor commands from CNS to PNS to effector cell?
Definition
Motor Neurons
Term
Which type of neuron analyzes and stores sensory information and makes decisions on how to react to it, the type that most neurons in the body are.
Definition
Interneurons (association neurons)
Term
What fills the space left by injured neurons that do not regenerate?
Definition
Neuroglia.
Term
What is found inbetween neurons that protects, supports, and nourishes them and makes up half the volume of the CNS?
Definition
Neuroglia.
Term
What are the Neuroglia cells of the CNS?
Definition
Astrocytes, oligodendrocytes, microglia, and ependymal cells.
Term
What are the neuroglia of the PNS?
Definition
Schwann cells, and satellite cells.
Term
What is a glioma?
Definition
A tumor of the neuroglia. Usually malignant and grow rapidly, very aggressive.
Term
What is any process coming off the cell body called?
Definition
Nerve Fiber (dendrites and axons).
Term
What is the control center of the neuron?
Definition
Cell Body or Soma.
Term
Where are Nissl Bodies found and what are they responsible for?
Definition
They are found in the cell body and they are responsible for protein synthesis, growth of the neuron and also aids in regeneration of the axon in the PNS.
Term
What are dendrites responsible for?
Definition
Receiving information (input).
Term
What is the one axon in each cell body responsible for?
Definition
Sending information to another neuron (output).
Term
What is the cone shaped elevation that connects the axon to the cell body?
Definition
Axon Hillock
Term
What is the 1st part of the axon called?
Definition
Initial Segment.
Term
What is the junction between the axon hillock and the initial segment?
Definition
Trigger Zone.
Term
Where are impulses initiated in most neurons then sent along the axon?
Definition
Trigger Zone.
Term
What is the swelling at the end of the axon terminal that contributes to the synapse?
Definition
Synaptic End Bulb.
Term
What is the site of communication between two neurons or a neuron and an effector cell?
Definition
Synapse.
Term
What is an effector cell?
Definition
A cell that is being targeted by a nerve impulse.
Term
What are the small sacs containing neurotransmitter found inside the synaptic end bulb?
Definition
Synaptic Vesicles.
Term
What is a neurotransmitter?
Definition
A chemical that carries an impulse from one neuron to another or from one neuron to an effector cell.
Term
What is the axon collateral?
Definition
The side branch of an axon.
Term
What is the fine process at the end of an axon collateral or axon?
Definition
Axon Terminal.
Term
What is the myelin sheath?
Definition
A fat and protein sheath covering the axon produced by neuroglia.
Term
What is the purpose of the myelin sheath?
Definition
To insulate the axon and speed the impulse conduction.
Term
What is the unit of neuroglia that produces myelin in the CNS?
Definition
Schwann Cell.
Term
What is the area of exposed axon between Schwann cells?
Definition
Node of Ranvier.
Term
What is the unit of neuroglia that produces myelin in the CNS?
Definition
Oligodendrocyte.
Term
What is the coating of Schwann that covers and protects the myelin sheath of neurons in the PNS?
Definition
Neurolemma.
Term
What helps regenerate an injury in the myelin sheath?
Definition
Neurolemma.
Term
Neurons of what division of the nervous system have no neurolemma?
Definition
CNS.
Term
What is the area of the spinal cord or brain that is comprised of myelinated processes of neurons?
Definition
White Matter.
Term
What is the area of spinal cord or brain comprised of unmyelinated processes of neurons?
Definition
Gray Matter.
Term
What is a multipolar neuron?
Definition
Many processes branching from the cell body.
Term
What is a bipolar neuron?
Definition
Two processes branching from the cell body.
Term
What is the one process that branches off the cell body and gives way to the axon and the dendrites?
Definition
Unipolar Neuron.
Term
What is an anaxonic neuron?
Definition
A neuron with no axon.
Term
What is the ability to change based on experience?
Definition
Plasticity.
Term
In what condition can damage to dendrites and myelinated axons be repaired in the PNS?
Definition
If the cell body remains intact, the schwann cells remain active and scar tissue does not grow too rapidly.
Term
Why is there little to no repair in the CNS tissue despite the condition of the cell body?
Definition
Because of the absence of the neurolemma.
Term
What is neurogenesis and where does it occur?
Definition
The creation or birth of new neurons in the CNS.
Term
What stimulates the formation and regeneration of CNS neurons and astrocytes (neuroglia) in the hippocampus?
Definition
Epidermal Growth Factor (EGF).
Term
What are the three reasons for poor nervous regeneration in the CNS?
Definition
1. No neurolemma created by the oligodendrocytes when forming the CNS myelin sheath
2. Absence of schwann cells makes tube regeneration impossible.
3. Astrocytes proliferate rapidly creating scar tissue and making a physical barrier to new neurons.
Term
What do the nerves in the PNS have that make a damaged axon have a good chance of repairing itself?
Definition
A neurolemma.
Term
What are the five steps to repair in the PNS?
Definition
1. Nissl bodies break down and spread through cell body.
2. Axon distal to the injury degnerates and breaks down leaving the neurolemma intact. (Wallerian Degeneration)
3. Proximal part of injured axon up to the Node of Ranvier breaks down. (Retrograde degeneration)
4. Schwann cells multiply and grow together creating a regeneration tube.
5. Regeneration tube guides the axon through re-growth across the injured area and into the space previously occupied by the distal axon.
Term
What is the conscious or subconscious awareness of external or internal stimuli?
Definition
Sensation
Term
What is the type of reaction generated by the sensation determined by?
Definition
The nerve impulse's ultimate CNS destination.
Term
The ultimate CNS destination of the Spinal Cord controls the:
Definition
Spinal Reflex
Term
The ultimate CNS destination of the Lower Brain stem controls the :
Definition
heart rate, breathing rate
Term
The ultimate CNS destination of the Thalamus of the brain controls the:
Definition
touch, pain, hearing taste, and crudeness of location.
Term
The ultimate CNS destination of the Cerebral cortex controls the:
Definition
precise locations
Term
What is the conscious awareness and interpretation of meaning of sensations?
Definition
Perception.
Term
What must happen in order for there to be the perception of a sensation?
Definition
It must reach the thalamus and cerebral cortex.
Term
What are sensory modalities?
Definition
Types of sensation, such as hearing, touch, pain adn vision.
Term
Each sensory neuron carries information for how many modalities?
Definition
One.
Term
What are the two types of general senses?
Definition
Somatic senses and visceral senses.
Term
What are the two classes of sensory modalities?
Definition
General senses and special senses.
Term
What are the somatic senses?
Definition
Tactile, thermal, pain and proprioception.
Term
What are the visceral senses?
Definition
The monitoring of conditions within the internal organs.
Term
What are the special senses?
Definition
Smell, taste, vision, hearing and equilibrium.
Term
What is a specialized cell or dendrite of a sensory neuron that monitors a particular condition in the internal or external environment?
Definition
Sensory Receptor
Term
What is the area of skin or tissue innervated by one sensory receptor?
Definition
Receptive Field.
Term
Each sensory receptor responds to how many types of stimulus?
Definition
One.
Term
What are the four steps of sensation?
Definition
1. Stimulation of the sensory receptor. (Within the receptive field)
2. Transduction of the stimulus. (Receptor converts stimulus to graded potential)
3. Generation of Impulses. (Graded potential creates an impulse that travels towards CNS)
4. Integration of Sensor Input. (Specific CNS region receives and interprets impulse)
Term
What are the sensory neurons that propagate nerve impulses from the PNS to the CNS?
Definition
First Order Neurons.
Term
What is the type of sensory receptor structure that consists of bare dendrites with no structural specialization?
Definition
Free nerve endings.
Term
What structure of the sensory receptors deals with pain, thermal, tickle, itch and some touch sensations?
Definition
Free nerve endings.
Term
What type of structure of the sensory receptors consists of dendrites enclosed in a connective tissue capsule?
Definition
Encapsulated nerve endings.
Term
What type of structure in sensory receptors consists of a synapse with first order neurons?
Definition
Separate Cells, that deal with the special senses.
Term
What is the type of potential that is produced by free nerve endings, encapsulated nerve endings, and olfactory receptors?
Definition
Generator potentials.
Term
What type of potential is produced by the special cells and is responsible for vision, hearing, taste and balance?
Definition
Receptor Potentials.
Term
This type of sensory receptor is found at or near the surface of the body and responsible for stimuli originating outside the body and provide information about the outside environment?
Definition
Exteroreceptors.
Term
What type of sensory receptors are located in the blood vessels, visceral organs, and nervous system that provide information about internal environment and conditions which are not consciously perceived?
Definition
Interoreceptors.
Term
What are the sensory receptors that are located in muscles, tendons, joints and the inner ear that are responsible for knowing body position and movement as well as muscle length and tension?
Definition
Proprioreceptors.
Term
What are the sensory receptors that detect mechanical pressure and stretching (i.e. touch, pressure, vibration, propioreception, hearing and balance.)?
Definition
Mechanoreceptors.
Term
What are the sensory receptors that detect changes in temperature?
Definition
Thermoreceptors.
Term
What are the types of sensory receptors that detect physical or chemical damage resulting in the perception of pain?
Definition
Nociceptors.
Term
What are the sensory receptors that detect light striking the retina?
Definition
Photoreceptors.
Term
What are the sensory receptors that detect chemicals in the mouth, nose and body fluids?
Definition
Chemoreceptors.
Term
What is adaptation in sensory receptors?
Definition
The decrease in amplitude of generator or receptor potentials during a maintained constant stimulus.
Term
What happens to the frequency of nerve impulses in a first order neuron during a prolonged stimulus?
Definition
They decrease.
Term
What type of sensory receptors adapt very quickly and are specialized for detecting changes in a particular stimulus?
Definition
Rapidly Adapting Receptors (Phasic).
Term
What type of sensory receptors adapt slowly and continue to trigger nerve impulses throughout a stimulus?
Definition
Slowly Adapting Receptors (Tonic).
Term
Do phasic or tonic receptors deal with pressure, touch and smell?
Definition
Phasic (Rapidly Adapting).
Term
Do phasic or tonic receptors deal with pain, body position and chemical composition of the blood?
Definition
Tonic (Slowly Adapting).
Term
What type of sensations deal with stimulation to the sensory receptors of the skin and subcutaneous layer, mucous membranes of the mouth, vagina, anus, muscles, tendons, joints and inner ear?
Definition
Somatic Sensations.
Term
What modalities do the somatic sensations have?
Definition
Tactile, thermal, nociception and proprioception.
Term
What modalities do the tactile sensations have?
Definition
Touch, pressure, vibration, itch and tickle.
Term
What are the two types of touch of the tactile sensations?
Definition
Crude touch and discriminative touch.
Term
What is the sense that something has contacted the skin?
Definition
Crude touch.
Term
What is the sense that gives specific information such as exact point touched, shape, size and texture?
Definition
Discriminative touch.
Term
What are the rapidly adapting touch receptors of discriminative touch located in the dermal papillae of hairless skin such as the finger tips and palms of the hand?
Definition
Meissner's Corpuscles.
Term
What are the rapidly adapting touch receptors found in hairy skin wrapped around the hair follicles?
Definition
Hair Root Plexuses.
Term
What are the slowly adapting touch receptors that are a free nerve ending, discriminative touch mechanoreceptors found in the fingers, lips and external genitalia?
Definition
Merkel discs.
Term
What are the slowly adapting touch receptors, encapsulated deep in the dermis, in the ligaments and tendons?
Definition
Ruffini Corpuscles.
Term
What is pressure received by?
Definition
Meissner and Pacinian corpuscles.
Term
What are the rapidly adapting receptors found in the dermis underlying mucous membranes, around joints, tendons, muscles, periosteum, mammary glands, external genitalia, pancreas and urinary bladder?
Definition
Pacinian Corpuscles.
Term
What are the rapidly adapting receptors found in the dermis underlying mucous membranes, around joints, tendons, muscles, periosteum, mammary glands, external genitalia, pancreas and urinary bladder?
Definition
Pacinian Corpuscles.
Term
What is received as rapidly repetitive sensory signals from tactile receptors using both Meissner and Pacinian corpuscles?
Definition
Vibration.
Term
What is the stimulation of free nerve endings by certain chemicals such as bradykinin and often the result of an inflammatory response?
Definition
Itch.
Term
What is the only sensation one can not elicit oneself? It is mediated by free nerve endings and Pacinian Corpuscles.
Definition
Tickle.
Term
At what temperatures are cold receptors activated?
Definition
10 to 40 degrees centigrade.
Term
At what temperatures are warm receptors activated?
Definition
Between 32 and 48 degrees centigrade.
Term
Below 20 degrees centigrade what kind of receptors receive temperature and what is the result?
Definition
Nociceptors receive the signal and results in pain.
Term
What protects human by signaling the presence of noxious, tissue-damaging conditions?
Definition
Pain perception
Term
What do nociceptors sense?
Definition
They sense tissue damage or noxious stimuli, not pain.
Term
What are nociceptors?
Definition
Free nerve endings in every tissue of the body except the brain.
Term
Intense thermal, mechanical or chemical stimuli activates what kind of sensory receptors?
Definition
Nociceptors.
Term
Why can pain continue even after the stimulus has been removed?
Definition
Because nociceptors are very slow adapting and the chemicals that stimulate them linger, causing pain to continue.
Term
What are the five types of pain?
Definition
Fast, slow, superficial somatic, deep somatic and visceral.
Term
What carries slow pain?
Definition
C fibers.
Term
What carries fast pain?
Definition
A-delta fibers (medium-diameter, myelinated axons)
Term
Chronic, burning, aching or throbbing pain in skin, deep tissues or internal organs would characterize what type of pain?
Definition
Slow pain.
Term
Acute, sharp or pricking pain not felt in deeper tissues of the body characterizes what type of pain?
Definition
Fast pain.
Term
Pain arising from the nociceptors of the skin characterizes what type of pain?
Definition
Superficial somatic pain.
Term
Pain arising from the nociceptors in the skeletal muscles, joints, tendons and fascia characterizes what type of pain?
Definition
Deep somatic pain.
Term
Pain that arises from nociceptors in the visceral organs characterizes what type of pain?
Definition
Visceral pain.
Term
What is pain that is not precisely localized to the area of injury or stimulus?
Definition
Referred pain.
Term
What makes referred pain possible?
Definition
The site of stimulus and the area where referred pain is felt are innervated by the same segments of the spinal cord.
Term
The sensation where a person can perceive touch, itch, vibration, or pain as coming from an amputated limb is called what?
Definition
Phantom limb sensation.
Term
How is phantom limb sensation possible?
Definition
Because the cerebral cortex interprets stimulus from the proximal axon of a neuron that used to go to the limb as still coming from that limb and neurons in the brain that previously received sensory impulses from the limb are still active.
Term
What type of sensation tells us about the body's position and movement in space?
Definition
Proprioceptive sensations.
Term
What is the perception of body movements?
Definition
Kinesthesia.
Term
The degree of muscle contraction, position of joints, tension of tendons and ligaments, and orientation of the head relative to the ground during movement all contribute to what sensation?
Definition
Proprioception.
Term
What are the proprioceptors within the skeletal muscle that detect sudden or prolonged stretch?
Definition
Muscle spindles.
Term
What are the proprioceptors that are found at the musculotendinous junction that protect against excessive tension?
Definition
Tendon organs.
Term
What do the muscle spindles do to stop muscle damage?
Definition
Send a message to the spinal cord which sends a motor response to involuntarily contract the muscle to stop stretching.
Term
What are the proprioceptors found in ligaments and joint capsules that adjust reflex inhibition of the adjacent muscles when excessive strain is placed on a joint?
Definition
Joint Kinesthetic Receptors.
Term
What are the two types of electrical signals in neurons?
Definition
Action potentials and graded potentials.
Term
What are action potentials?
Definition
Communication over short and long distances.
Term
What are graded potentials?
Definition
Communication over short distances only.
Term
What is the difference in charge on the inside of the membrane versus the charge on the outside of the membrane creating a voltage difference across the membrane that acts as potential energy?
Definition
Membrane potential.
Term
Why do graded and action potentials take place?
Definition
Because ion channels in the membrane open and close allowing charged ions to pass through.
Term
What are the two main types of ion channels?
Definition
Leakage channels and gated channels.
Term
What are the three kinds of gated channels?
Definition
Voltage-gated ion channels, ligand-gated ion channels and mechanically-gated ion channels.
Term
Which type of ion channel opens in response to a chance in membrane potential and are used in action potentials?
Definition
Voltage-gated ion channels.
Term
Which type of ion channel opens and closes in response to specific chemical stimuli and is found in auditory receptors in the ears, monitor stomach stretching and as touch receptors in the skin?
Definition
Mechanically-gated ion channels.
Term
How is resting membrane potential created?
Definition
Through an equal buildup of anions inside the cell membrane and cations outside the cell membrane.
Term
What is potential energy measured in and what does it average at?
Definition
It is measured in millivolts and averages at -70mV.
Term
What is it called when the cell maintains the normal membrane potential?
Definition
Polarization.
Term
What is called when due to the opening of ion channels in the cell's membrane, positive ions are allowed to enter the cytoplasm and make the potential less negative?
Definition
Depolarization.
Term
What is it called when due to opening of ion channels in the cell's membrane, negative ions are allowed to enter the cytoplasm and make the potential more negative?
Definition
Hyperpolarization.
Term
What two factors maintain the resting membrane potential?
Definition
The unequal distribution of ions across the cell membrane (Na+ and Cl- on outside of cell and K+ on inside). And, the membrane being 50-100 times more permeable to K+ than to Na+.
Term
What are the steps of an action potential?
Definition
Resting state, depolarization (threshold), repolarization and refractory period.
Term
When Na+ channels allow Na+ to rush into a cell what does it cause?
Definition
Depolarization.
Term
When K+ channels allow K+ to rush out of a cell what does it cause?
Definition
Repolarization.
Term
How do impulses travel from one body part to another?
Definition
Propagation.
Term
What is continuous conduction?
Definition
Unmyelinated axons conducting impulses by depolarizing each adjacent portion of the axon.
Term
What is saltatory conduction?
Definition
When in myelinated axons, only the nodes of ranvier need to be depolarized and the impulse appears to leap across the membrane from node to node very quickly.
Term
What are the two determinants of the speed of nerve impulse propagation?
Definition
1. Diameter of axon 2. myelination.
Term
What fiber has the largest diameter axons, are myelinated, and a small refractory period?
Definition
A Fibers.
Term
Which fiber has the 2nd largest diameter axons, is myelinated, and has a small refractory period?
Definition
B Fibers.
Term
Which fiber has the smallest axon diameter, is unmyelinated, and has a long refractory period?
Definition
C Fibers.
Term
What is the intensity of a stimulus determined by?
Definition
The frequency of impulses and number of neurons stimulated, not by the strength of stimulus.
Term
What carries the electrical impulse across the synapse from the neuron to the second neuron or effector cell?
Definition
Gap Junctions.
Term
Where are gap junctions seen?
Definition
visceral smooth muscle, cardiac muscle, and developing embryos.
Term
What are the advantages to an electrical synapse?
Definition
Faster communication, synchronization of group fibers, and with a two-way transmission it can move back and forth.
Term
What is the method by which one neuron transfers its action potential to another neuron or its target cell?
Definition
Chemical Synapse.
Term
What is it called when the synapse depolarizes the effector cell but less than threshold and causes the post-synaptic membrane to become more excitable since it is closer to threshold than normal?
Definition
EPSP (Excitatory Post Synaptic Potential)
Term
What is it called when the synapse hyperpolarizes the efector cell and causes the post-synaptic membrane to become less excitable since it is farther from threshold than normal?
Definition
IPSP (Inhibitory Postsynaptic Potential)
Term
What is it called when an EPSP is enough to reach threshold and fire an action potential?
Definition
Nerve impulse.
Term
What is it called when an action potential is fired by a neurotransmitter from several presynaptic endbulbs?
Definition
Spatial Summation.
Term
What is it called when an action potential is fired by a build up of neurotransmitter released from one presynaptic end bulb?
Definition
Temporal Summation.
Term
What will happen if the neurotransmitter is not removed from the synaptic cleft when the action potentials stop?
Definition
They will continue to stimulate the receptors on the postsynaptic membrane, resulting in overstimulation (if an excitatory neurotransmitter) or over inhibition (if an inhibitory neurotransmitter).
Term
What are the three methods of removal of a neurotransmitter from the postsynaptic cleft?
Definition
1. Diffusion into the ECF
2. Enzymatic degradation
3. Re-uptake by presynaptic membrane
Term
What is an agent that enhances synaptic transmission or mimics the natural effect of a neurotransmitter?
Definition
Agonist.
Term
What is an agent that blocks the action of a neurotransmitter?
Definition
Antagonist.
Term
What are the two classes that neurotransmitters can be divided into?
Definition
Small-molecule neurotransmitters and neuropeptides.
Term
What are the three kinds of small-molecule neurotransmitters?
Definition
Acetylcholine (ACh), Amino Acids and Biogenic Amines.
Term
This neurotransmistter is released by PNS neurons and some CNS neurons, it can be inhibitory or excitatory, what is it?
Definition
Acetylcholine (ACh).
Term
This amino acid is mostly used as the building block of proteins, but is also used as a neurotransmitter, what is it?
Definition
Amino acid.
Term
What happens when ACh (acetylcholine) is excitatory?
Definition
It goes to neuromuscular junction to create muscular contractions.
Term
What happens when ACh (acetylcholine) is inhibitory?
Definition
It slows the heart rate via the vagus nerve.
Term
What makes ACh (acetylcholine) inactive how does it do this?
Definition
The enzyme acetylcholine esterase breaks it down into acetate and choline.
Term
What are the two excitatory amino acids?
Definition
Glutamate and aspartate.
Term
What are the two inhibitory amino acids?
Definition
GABA (gamma aminobutyric acid) and glycine.
Term
What is the most common inhibitory transmitter in the brain?
Definition
GABA.
Term
What are the four biogenic amines?
Definition
Norepinephrine, epinephrine, dopamine and seratonin.
Term
What are the biogenic amines used for waking up, dreaming and regulating mood that are released by the adrenal gland and also known as adrenaline?
Definition
Norepinephrine and epinephrine.
Term
What is the biogenic amine that is involved in emotional responses and skeletal muscle tone?
Definition
Dopamine.
Term
What is the biogenic amine that is found in the brain and is thought to be involved in sensory perception, temperature regulation, mood control and induction of sleep?
Definition
Seratonin.
Term
What are the three neuropeptides with strong analgesic properties?
Definition
Enkaphalin, endorphin and dynorphin.
Term
What is the neuropeptide that transmits pain-related impulses from the PNS to the CNS?
Definition
Substance P.
Term
What neuropeptide suppresses the release of substance P?
Definition
Enkaphalin.
Term
Where is the spinal cord located? What surrounds and protects it?
Definition
It is located in the vertebral canal surrounded by the vertebrae.
Term
The vertebrae, spinal meninges, vertebral ligaments and cerebrospinal fluid all do what for the spinal cord?
Definition
Protect it.
Term
What is the three-layer connective tissue protective covering of the spinal cord?
Definition
Spinal meninges.
Term
What is the superficial layer of the spinal meninges made of dense irregular connective tissue?
Definition
Dura Mater.
Term
What is the middle layer of the spinal meninges?
Definition
Arachnoid Mater.
Term
What is the space between the arachnoid mater and the dura mater called?
Definition
Subdural space.
Term
What is the innermost layer of the spinal meninges that is made of a thin transparent layer of CT that adheres to the brain and spinal cord?
Definition
Pia Mater.
Term
Which of the layers of the spinal meninges is avascular?
Definition
Arachnoid Mater.
Term
What are blood vessels sheathed by as they supply the spinal cord with oxygen and nutrients?
Definition
Pia Mater.
Term
What is the space between the arachnoid mater and pia mater called?
Definition
Subarachnoid space.
Term
What are the triangular-shaped membranous extensions of the pia mater suspending the spinal cord within the dural sheath?
Definition
Denticulate ligaments.
Term
What protects the spinal cord from shock and sudden displacement?
Definition
Denticulate ligaments.
Term
Where does the spinal cord run?
Definition
From the medulla oblongata to the superior border of the 2nd lumbar vertebra.
Term
Where are the two enlargements in the length of the spinal cord?
Definition
Cervical enlargement from C4 to T1 and Lumbar enlargement from T9 to T12.
Term
What is the conical tapering of the spinal cord at it's most inferior aspect (around the L1/L2 level)?
Definition
Conus Medullaris.
Term
What is the extension of the pia mater that arises from the conus medullaris and continues to the coccyx?
Definition
Filum terminale.
Term
What anchors the spinal cord to the coccyx?
Definition
Filum terminale.
Term
What are the bilateral paths of communication between the spinal cord and the nerves innervating specific regions of the body?
Definition
Spinal nerves.
Term
Each spinal nerve is connected to the spinal cord by what?
Definition
Two bundles of axons called roots.
Term
How many pairs of cervical, thoracic, lumbar, sacral and coccygeal nerves are there?
Definition
8 cervical, 12 thoracic, 5 lumbar, 5 sacral and 1 coccygeal.
Term
Where do sensory impulses enter the spinal cord?
Definition
On neurons in the dorsal roots.
Term
What is the swelling in the dorsal nerve root that contains the cell bodies of sensory neurons?
Definition
Dorsal root ganglion.
Term
Where do motor impulses leave the spinal cord?
Definition
On axons in the ventral roots.
Term
Where are white matter and gray matter located?
Definition
In the spinal cord.
Term
What is the unmyelinated nerve tissue that forms a butterfly-shape in the center of the spinal cord with its 'wings' reaching the superficial corners of the cord?
Definition
Gray matter.
Term
What is the myelinated and unmyelinated nerve tissues that surrounds the gray matter?
Definition
White matter.
Term
What are the three sections that the gray matter is divided up into?
Definition
Ventral gray horns, dorsal gray horns, and lateral gray horns.
Term
What is the section where the gray matter extends toward the anterior aspects of the spinal cord that contains motor neurons that will carry the impulses that contract skeletal muscle?
Definition
Ventral Gray Horns.
Term
What is the section where the gray matter extends toward the posterior aspects of the spinal cord that contain sensory nuclei?
Definition
Dorsal gray horns.
Term
What are the small extensions of gray matter laterally that do not reach the superficial aspect of the spinal cord that contain motor neurons that carry impulses from the autonomic nervous system that regulate smooth muscle, cardiac muscle and glands?
Definition
Lateral gray horns.
Term
What are the three sections that white matter is divided into bilaterally?
Definition
Anterior white columns, posterior white columns and lateral white columns.
Term
What are the columns of white matter that contain bundles of axons with common origin or destination that carry similar information called?
Definition
Tracts.
Term
What are the ascending tracks of white matter that conduct nerve impulses towards the brain (ascending) called?
Definition
Sensory tracts.
Term
What are the columns of white matter that conduct nerve impulses from the brain down the spinal cord (descending) called?
Definition
Motor tracts.
Term
What are the three ways that the tracts along the spinal cord white matter can be named?
Definition
1. Position in the cord's white matter.
2. Where it begins and ends.
3. The direction of nerve impulse propagation.
Term
What is the rule regarding the naming of tracts?
Definition
The position of the dendrites and cell bodies comes first and the position of the axon terminals comes last in the name of the tract.
Term
Which route on the spinal cord carries impulses sensing pain, temperature, deep pressure and crude touch?
Definition
Spinothalamic tracts.
Term
Which route on the spinal cord carries impulses sensing proprioception, discriminative touch, two point discrimination, pressure and vibration?
Definition
Posterior (Dorsal) Columns.
Term
What are the two primary routes with with sensory information from receptors travel to the brain?
Definition
Spinothalamic tracts and posterior columns.
Term
What are the two ways that motor output travels from the brain down the spinal cord descendingly?
Definition
Direct and indirect pathways.
Term
This motor output that travels from the brain down the spinal cord carries nerve impulses from the cerebral cortex down the spinal cord to initiate precise voluntary movements of skeletal muscle, which is it?
Definition
Direct pathway.
Term
What are the three tracts of the direct pathways?
Definition
Lateral corticospinal, anterior corticospinal, and corticobulbar tracts.
Term
Which motor output travels from the brain down the spinal cord and carries nerve impulses from the brain/brainstem down the spinal cord to program automatic movements, help coordinate body movements with visual stimuli, maintain skeletal muscle tone and posture and plays a role in equilibrium?
Definition
Indirect pathways.
Term
What are the three indirect pathways tracts?
Definition
Rubrospinal, tectospinal, and vestibulospinal tracts.
Term
What are fast, predictable, automatic responses to changes in the environment?
Definition
Reflexes.
Term
Which reflex originates in the brain stem and travels through the cranial nerves?
Definition
Cranial reflexes.
Term
Which reflexes involve contraction of the skeletal muscles?
Definition
Somatic reflexes.
Term
Which reflexes involves responses of smooth muscle, cardiac muscle and glands and are not perceived?
Definition
Autonomic reflexes.
Term
What is the pathway that a nerve impulse takes to create a reflex?
Definition
Reflex arc.
Term
What are the five functional components of a reflex arc?
Definition
Sensory receptor, sensory neuron, integrating center, motor neuron, and effector.
Term
What is a single sensory neuron creating a synapse with a single motor neuron in the integrating center known as?
Definition
A monosynaptic reflex arc.
Term
What is it called when the integrating center requires one or more interneurons to carry the impulse from the sensory neuron to the motor neuron within the gray matter?
Definition
Polysynaptic reflex arc. (More common)
Term
What carries the motor command initiated by the integrating center out of the CNS to the part of the body needed to respond to the stimulus?
Definition
Motor Neuron.
Term
What is the part of the body that responds to the motor nerve impulse?
Definition
Effector.
Term
What is the action of the effector?
Definition
A reflex.
Term
If the effector cell is a skeletal muscle what is its action called?
Definition
Somatic reflex.
Term
If the effector cell is smooth muscle, cardiac muscle or a gland what is its action called?
Definition
Autonomic reflex.
Term
What responds to a specific stimulus and initiates a nerve impulse if the stimulus is strong enough?
Definition
Sensory receptor.
Term
What propagates the nerve impulse initiated by a receptor?
Definition
Sensory neuron.
Term
What is the section of gray matter in the CNS that allows the sensory neuron and the motor neuron to communicate?
Definition
Integrating center.
Term
Why can reflexes gives us useful information on the state of the nervous system?
Definition
Because they are very predictable.
Term
What is the monosynaptic reflex designed to do?
Definition
Protect the muscle from over stretching.
Term
What are the five steps to a stretch reflex?
Definition
1. Muscle stretch stimulates muscle spindles.
2. Muscle spindle generates nerve impulse that travels along somatic sensory neuron through dorsal root into dorsal horn of spinal cord.
3. Synapse created between sensory and motor neuron in integrating center (gray matter)
4. If strong enough, synapse's EPSP initiates an impulse along motor neuron through peripheral nerves to appropriate muscle.
5. ACh is released at the Neuromuscular junction creating muscle action potentials in the stretched muscle causing it to contract and counteract stretching.
Term
What is it called when the muscle of the stretch reflex is contracting and the muscle that opposes that muscles relaxes?
Definition
Reciprocal innervation.
Term
What is it called when the motor impulse leaving the spinal cord is on the same side that the sensory impulse enters on?
Definition
Ipsilateral reflex arc.
Term
What is muscle tone regulated by?
Definition
The brain.
Term
How does muscle keep its normal tone?
Definition
The brain allows muscle spindles to variably activate keeping a light level of contraction in the muscles that give it its normal tone.
Term
What controls muscle tension by relaxing the muscle to protect from injury caused by overtension?
Definition
The tendon reflex.
Term
What type of reflex arc is the tendon reflex?
Definition
Ipsilateral.
Term
What are the five steps of the tendon reflex?
Definition
1. Tension on muscle stimulates the tendon organ sensory receptor.
2. Nerve impulses propagate along a sensory neuron in the dorsal root of the spinal nerve and into the dorsal horn of the spinal cord.
3. Sensory neuron synapses in the spinal cord's gray matter with an inhibitory interneuron which synapses with a motor neuron.
4. Neurotransmitter inhibits the motor neuron to that muscle generating fewer nerve impulses (IPSP).
5. Overtensed muscle relaxes and tension is relieved.
Term
What is the polysynaptic reflex that is designed to protect you from a potentially harmful stimulus?
Definition
Flexor or withdrawal reflex.
Term
What type of reflex is the flexor/withdrawal reflex?
Definition
Ipsilateral polysynaptic.
Term
What are the five steps to the flexor/withdrawal reflex?
Definition
1. Nociceptors stimulated by tack.
2. Nerve impulse propagates to spinal cord.
3. Sensory neuron activates interneurons that extend to many spinal cord segments.
4. Interneurons activate many motor neurons from many different spinal cord segments generating nerve impulses along peripheral nerves toward the muscles.
5. ACh released into synapse of the NMJ stimulating the muscles of the thigh to contract pulling leg away from tack.
Term
When the muscle stimulated is controlled by a different spinal segment than the sensory area stimulated what type of reflex arc is it considered?
Definition
Intersegmental reflex arc.
Term
The crossed extensor reflex is what kind of reflex?
Definition
Polysynaptic, contralateral reflex arc.
Term
What are the five steps to the crossed extensor reflex arc?
Definition
1. Tack stimulates nociceptor in right foot.
2. Nerve impulses travel to spinal cord.
3. in spinal cord, sensory neuron activates several interneurons that cross the anterior and posterior gray commisures at several spinal cord levels above and below the initial stimulation.
4. Interneurons synapse and excite motor neurons on the left side generating nerve impulses toward the periphery of the body.
5. Neurons release ACh into the NMJs of the extensor muscles on the LEFT thigh causing it to straighten and prepare to bear weight to balance.
Term
What type of innervation occurs in both the crossed extensor and flexor/withdrawal reflexes?
Definition
Reciprocal innervation.
Term
What do spinal nerves and their branches do?
Definition
Serve all parts of the body and connect the CNS to the muscles, sensory receptors and glands.
Term
To which nervous system to spinal nerves belong?
Definition
PNS.
Term
How many pairs of spinal nerves are named and numbered for the vertebral level from which they emerge from the spinal cord?
Definition
31 pairs.
Term
All spinal nerves emerge from the intervertebral foramen (IVF) except which? Where does it emerge from?
Definition
The C1 nerve which emerges from between he atlas C1 and the occipital bone of the skull.
Term
What is a spinal nerve made up of ?
Definition
A dorsal and ventral root from the spinal cord and has both sensory and motor neurons- considered a mixed nerve.
Term
What is a mixed nerve?
Definition
One that contains both sensory and motor neurons.
Term
What is endoneurium?
Definition
The connective tissue covering of the axon.
Term
What is a group of axons called? What are they surrounded by?
Definition
They are called a fascicle and are surrounded by perineurium.
Term
What is a group of fascicles bundled together along with blood vessels and fat and are surrounded by epineurium?
Definition
Spinal nerve.
Term
What are the branches that spinal nerves divide into after exiting the IVF called?
Definition
Rami or one ramus.
Term
What innervates the deep muscles and skin of the posterior surface of the trunk?
Definition
Dorsal ramus.
Term
What innervates the muscles of the upper and lower limbs and the skin of the anterior and lateral surfaces of the trunk?
Definition
Ventral ramus.
Term
What innervates the vertebrae, vertebral ligaments, blood vessels of the spinal cord and meninges when it re-enters the IVF?
Definition
Meningeal branch.
Term
What innervate components of the autonomic nervous system?
Definition
Rami Communicantes.
Term
What is a network of nerves made up of multiple nerve fibers from anterior rami and adjacent nerves?
Definition
Plexus.
Term
What are the four pairs of major plexuses?
Definition
Cervial, brachial, lumbar and sacral plexuses.
Term
What nerves emerge from the T2-T12 spinal nerves to travel in between the ribs and innervate structures in their immediate area?
Definition
Intercostal nerves.
Term
Which plexus innervates the skin, muscles of the head, neck, superior part of the shoulders and chest, motor diaphragm via the phrenic nerve and motor to the deep muscles, levator scapulae and middle scalene muscles?
Definition
Cervical plexus.
Term
Which plexus innervates the shoulder and upper limbs?
Definition
Brachial plexus.
Term
The axillary emerging nerve innervates what muscles?
Definition
Deltoid and teres muscles.
Term
The musculocutaneous nerve, emerging from the brachial plexus, innervates what muscles?
Definition
Biceps brachii, coracobrachialis, and brachialis.
Term
The radial emerging nerve innervates what muscles?
Definition
Triceps brachii and forearm extensors.
Term
The median emerging nerve innervates what muscles?
Definition
Most of the forearm flexors.
Term
The ulnar emerging nerve innervates what muscles?
Definition
Most hand muscles, and some forearm flexors.
Term
Which plexus innervates the anterolateral abdominal wall, external genitals and part of the lower limbs?
Definition
Lumbar plexus.
Term
The femoral nerve emerging from the lumbar plexus innervates what muscles?
Definition
Hip flexors and quads.
Term
The obturator nerves emerging from the lumbar plexus innervate what muscles?
Definition
Adductors of the hip.
Term
Which plexus innervates the buttocks, perineum and lower limbs?
Definition
Sacral plexus.
Term
The sciatic nerve, emerging from the sacral plexus innervates what muscles?
Definition
Hamstrings and adductor magnus.
Term
The tibial nerve, emerging from the sacral plexus, innervates what muscles?
Definition
Gastrocnemius, soleus, plantaris, popliteus, and some plantar flexors of the foot.
Term
What are the specific sections of skin innervated by sensory neurons that send information to one specific spinal nerve root?
Definition
Dermatomes.
Term
What relays information from the somatic sensory receptors to the primary somatosensory area in the cerebral cortex and/or the cerebellum?
Definition
Somatic Sensory pathways.
Term
What is the primary somatosensory area of the brain known as?
Definition
Post-central gyrus.
Term
Which neurons conduct impulses from the somatic sensory receptors to the spinal cord or brainstem?
Definition
First-order neurons.
Term
Which neurons conduct impulses from the spinal cord or brainstem to the thalamus?
Definition
Second-order neurons.
Term
Which neurons conduct impulses from the thalamus to the primary somatosensory area of the cerebral cortex where conscious perception of the sensation results?
Definition
Third-order neurons.
Term
The cerebral cortex controls what kind of body movements?
Definition
Precise, discrete muscular movements.
Term
The basal ganglia controls what body movements?
Definition
It establishes a normal level of muscle tone and integrates semivoluntary and automatic movements.
Term
What does the cerebellum do towards controlling body movements?
Definition
It assists cortex and basal ganglia in making body movements smooth and coordinated by maintaining balance and posture.
Term
What propagates motor command impulses from the brain to the skeletal muscles?
Definition
Direct Motor Pathways.
Term
What are neurons within the brain and spinal cord gray matter?
Definition
Upper motor neurons.
Term
What are the motor neurons with pathways from the anterior horn of the spinal cord to the skeletal muscles?
Definition
Lower motor neurons.
Term
What neurons travel down the spinal cord and synapse with an interneuron which then synapses with a lower motor neuron?
Definition
Upper motor neuron.
Term
If there is a lesion of a lower motor neuron what type of paralysis is the result?
Definition
Ipsilateral flaccid paralysis.
Term
If there is a lesion of an upper motor neuron what type of paralysis is the result?
Definition
Contralateral spastic paralysis.
Term
Are astrocytes part of the peripheral nervous system?
Definition
No.
Term
What is the result if a neurotransmitter hyperpolarizes the post-synaptic membrane?
Definition
IPSP
Term
Chemicals that carry messages or impulses within the nervous system are called what?
Definition
Neurotransmitters.
Term
What is A?nerve 1
Definition
Nucleus of a neuron.
Term

What is B?

 

nerve 1

Definition
Axon hillock.
Term

What is C?

 

nerve 1

Definition
Node of ranvier.
Term

What is D?

 

nerve 1

Definition
Axon.
Term

What is E?

 

nerve 1

Definition
Myelin sheath.
Term

What is F?

 

nerve 1

Definition
Schwann cell.
Term

What is G?

 

nerve 1

Definition
Synaptic end bulb.
Term

What is H?

 

nerve 1

Definition
Neuroglia.
Term

What is I?

 

nerve 1

Definition
Nucleus of a schwann cell.
Term

What is J?

 

nerve 1

Definition
Dendrite.
Term

What is A?

 

histo lab 2

Definition
Neuron cell body.
Term

What is B?

 

histo lab 2

Definition
Neuroglia.
Term
Definition
Term

What is the arrow pointing to?

 

astrocytes 3

Definition
Astrocytes.
Term

What does this slide show?

 

pacinian corpuscle 4

Definition
Pacinian corpuscle.
Term

What is A?

 

synapse 6

Definition
Synaptic vessicle.
Term

What is B?

 

synapse 6

Definition
Neurotransmitter.
Term

What is C?

 

synapse 6

Definition
Post-synaptic membrane.
Term

What is D?

 

synapse 6

Definition
Sodium ion channel.
Term

What is E?

 

synapse 6

Definition
Calcium ion channel.
Term

What is A?

 

synapse 7

Definition
Synaptic vessicle.
Term

What is B?

 

synapse 7

Definition
Axon terminal.
Term

What is C?

 

synapse 7

Definition
Synaptic end bulb.
Term

What is D?

 

synapse 7

Definition
Synaptic cleft.
Term

What is E?

 

synapse 7

Definition
Post-synaptic membrane.
Term
Reciprocal innervation of the tendon reflex in the quadriceps muscle group results in what?
Definition
Hamstring contraction.
Term
Where does the C4 spinal nerve exit?
Definition
Above the C4 vertebra.
Term

What is A?

 

spinal nerve diag 8

Definition
Dorsal ramus.
Term

What is B?

 

spinal nerve diag 8

Definition
Ventral ramus.
Term

What is C?

 

spinal nerve diag 8

Definition
Spinal nerve.
Term

What is D?

 

spinal nerve diag 8

Definition
Dorsal horn of gray matter.
Term

What is E?

 

spinal nerve diag 8

Definition
Meningeal branch.
Term

What is F?

 

spinal nerve diag 8

Definition
Rami communicantes.
Term

What is A?

 

spinal cord lab 9

Definition
Spinal nerve.
Term

What is B?

 

spinal cord lab 9

Definition
Filum terminale.
Term

What is C?

 

spinal cord lab 9

Definition
Cauda equina.
Term

What is D?

 

spinal cord lab 9

Definition
Conus medullaris.
Term

What is A?

 

cerv vert 10

Definition
Dorsal root ganglion.
Term

What is B?

 

cerv vert 10

Definition
Cervical spinal cord.
Term

What is C?

 

cerv vert 10

Definition
Ventral root.
Term

What is D?

 

cerv vert 10

Definition
C4 spinal nerve.
Term

What is E?

 

cerv vert 10

Definition
Dorsal rootlets.
Term

What is A?

 

periph nerve 11

Definition
Femoral nerve.
Term

What is B?

 

periph nerve 11

Definition
Lateral cutaneous nerve.
Term

What is C?

 

periph nerve 11

Definition
Superficial fibular nerve.
Term

What is D?

 

periph nerve 11

Definition
Deep fibular nerve.
Term

What is E?

 

periph nerve 11

Definition
Saphenous nerve.
Term

What is 2a?

 

nerve cross

 

 

Definition
Axon.
Term

What is 2b?

 

nerve cross

Definition
Myelin.
Term

What is 2c?

 

nerve cross

Definition
Endoneurium.