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Neisseria and Moraxella (Gram Negative cocci/diplococci)
Midterm Medical Microbiology
11
Microbiology
Undergraduate 3
03/27/2010

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Term
Neisseria General Characteristic
Definition
Aerobic, non-motile, non spore forming, gram negative diplococci, capnophilic
Term
Neisseria Gonorrhoeae Virulence Factors
Definition
1. Receptors for human transferrin
2. Capsule - antiphagocytic
3. Pili - attachment to cells
4. Antigenic Variation
5. LPS- Endotoxin
6. IGA Protease
7. Beta-lactamase
Term
Clinical Manifestations of N. Gonorrhoeae
Definition
Infections : Genital, Rectal, Pharyngeal, PID, Disseminated Gonococcal infections, Conjunctivitis
Term
Lab Diagnosis of N. G
Definition
Oxidase +
Usually intracellular
Non-motile and Non-sporogenous
Term
CTA carbohydrate test results N.G
Definition
Oxidase +
Glucose +
Maltose -
Lactose -
Sucrose -
Term
CTA carbohydrate test results N Meningitidis
Definition
Oxidase +
Gluose +
Maltose +
Lactose and Sucrose -
Term
CTA carbohydrate test results N Lactamica
Definition
Oxidase, glucose,maltose, and lactose + sucrose -
Term
CTA carbohydrate test results M. Catarhalis
Definition
Oxidase +
glucose, maltose, lactose and sucrose -
Term
Neisseria Meningitidis Clinical Manifestations
Definition
Meningitis
Term
Meningitis
Definition
Peak incidence in young adults (college)
Symptoms include: abrupt onset severe headache, stiff neck, sometimes fever, petechial rash, paralysis, coma and death.
Term
Moraxella Catarhalis General Characteristics
Definition
Upper respiratory tract
gram negative coccobacilli or diplococci
oxidase and catalase positive
produces DNAse
non-fermentative
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