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Murali Drugs
N/A
86
Pharmacology
Graduate
01/07/2012

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Cards

Term
Acetylcholine
Definition

Muscarinic, Nicotinic Agonist

Susceptible to ACHE breakdown

Term
Bethenechol
Definition
Muscarinic Agonist (Also AchE-I effect)
Term
Carbachol
Definition
Muscarinic, Nicotinic Agonist (Also ACHE-I effect)
Term
Methacholine
Definition
Muscarinic Agonist (Respiratory Diagnostic)
Quat.
Susceptible to ACHE breakdown
Term
Arecholine
Definition
Muscarinic, Nicotinic Agonist
Term
Muscarine
Definition
Muscarinic Agonist
Tert. Can be taken orally for systemic effect.
Term
Pilocarpine
Definition
Muscarinic Agonist
Tert. Can be taken orally for systemic effect.
Term
AF267B
Definition
Muscarinic Agonist
Clinical Trial for alzheimer's
Term
Cevimiline
Definition
Muscarinic Agonist
Tert. Can be taken orally for systemic effect. For Sjogren's
CYP metabolized/interactions.
Term
Nicotine
Definition
Nicotinic Agonist
Term
ABT-418
Definition
Nicotinic Agonist
Term
Epibatidine
Definition
Nicotinic Agonist
Term
SIB-1508Y
Definition
Nicotinic Agonist
Term
Varenicline
Definition
Partial Nicotinic Agonist
For smoking cessations
Term
Ambenonium
Definition
Reversible ACHE Inhibitor
Quat. For Myasthenia Gravis
Term
Donepezil
Definition
Reversible ACHE Inhibitor
Crosses BBB
CYP metabolized/interactions.
Term
Edrophonium
Definition
Reversible ACHE Inhibitor
Quat. Diagnostic for Myasthenia Gravis
Term
Galantamine
Definition
Reversible ACHE Inhibitor
Crosses BBB.
CYP metabolized/interactions.
Term
Tacrine
Definition
Reversible ACHE Inhibitor
Crosses BBB.
CYP hepatotoxicity/interactions.
Term
Demacarium
Definition
Semi-reversible ACHE Inhibitor
Quat. "Bis-Neostigmine"
Term
Physostigmine
Definition
Semi-reversible ACHE Inhibitor
Tert. Can cross BBB. For treating CNS toxicity of anti-Achs.
Term
Pyridostigmine
Definition
Semi-reversible ACHE Inhibitor
Quat.
Term
Neostigmine
Definition
Semi-reversible ACHE Inhibitor (Also direct Ach Agonist)
Quat.
Term
Rivastigmine
Definition
Semi-reversible ACHE Inhibitor
Tert. Can cross BBB. For Alzheimer's
Term
Organophosphorus
Definition
Irreversible ACHE Inhibitor
Term
Sarin
Definition
Irreversible ACHE Inhibitor (Nerve Gas)
Term
Soman
Definition
Irreversible ACHE Inhibitor (Nerve Gas)
Term
Tabun
Definition
Irreversible ACHE Inhibitor (Nerve Gas)
Term
Malathion
Definition
Irreversible ACHE Inhibitor (Pesticide)
Term
Parathion
Definition
Irreversible ACHE Inhibitor (Pesticide
Term
Echothiophate
Definition
Irreversible ACHE Inhibitor (Therapeutic)
Quat. For Glaucoma. Cannot be absorbed systemically through skin.
Term
Isofluorophate
Definition
Irreversible ACHE Inhibitor (Therapeutic)
Can be absorbed systemically through skin.
For Glaucoma.
Term
Atropine
Definition
Muscarinic Blocker
Tert.
Term
Scopolamine
Definition
Muscarinic Blocker
Tert.
Term
Homatropine
Definition
Muscarinic Blocker
Tert. For inducing mydriasis and produces cycloplegia during eye exams.
Term
Ipratropium
Definition
Muscarinic Blocker
Quat. For bronchospasm/COPD
Term
Methscopolamine
Definition
Muscarinic Blocker
Quat.
Term
Tiatropium
Definition
Muscarinic Blocker
Quat. For bronchospasm/COPD
Term
Pirenzepine
Definition
M-1 Blocker
For Peptic Ulcers
Term
Telenzepine
Definition
M-1 Blocker
For Peptic Ulcers
Term
Methoctramine
Definition
M-2 Blocker
For CVS failure
Term
Darifenacin
Definition
M-3 (The most selective)
Tert. For overactive bladder.
CYP metabolism/interactions
Term
Solifenacin
Definition
M-3 Blocker
Tert. For overactive bladder.
CYP metabolism/interactions
Term
Benztropine
Definition
Muscarinic Blocker
For Parkinson's
Term
Cyclopentolate
Definition
Muscarinic Blocker
Tert.
Term
Dicyclomine
Definition
Muscarinic Blocker
Tert.
Term
Flavoxate
Definition
Muscarinic Blocker
Tert.
Term
Fosterodine
Definition
Muscarinic Blocker
Term
Glycopyrollate
Definition
Muscarinic Blocker
Term
Methantheline
Definition
Muscarinic Blocker
Term
Methixene
Definition
Muscarinic Blocker
Tert.
Term
Oxybutynin
Definition
Muscarinic Blocker
Tert.
Term
Oxyphencyclimine
Definition
Muscarinic Blocker
Tert.
Term
Propenthaline
Definition
Muscarinic Blocker
Quat. For peptic Ulcers, Hyperhidrosis,
Term
Tolterodine
Definition
Muscarinic Blocker
Tert. For overactive bladder
CYP metabolism/interactions
Term
Trihexiphenidyl
Definition
Muscarinic Blocker
For Parkinson's
Term
Tropicamide
Definition
Muscarinic Blocker
Tert. For inducing mydriasis and produces cycloplegia during eye exams.
Term
Trospium
Definition
Muscarinic Blocker
Tert.
Term
Anti-histamine
Definition
Muscarinic Block Side effect
Term
Anti-psychotic
Definition
Muscarinic Block Side effect
Term
Anti-depressant
Definition
Muscarinic Block Side effect
Term
Anti-arrhythmic
Definition
Muscarinic Block Side effect
Term
Hexamethonium
Definition
Ganglionic Nicotinic Blocker.
Term
Mecamylamine
Definition
Ganglionic Nicotinic Blocker.
Crosses BBB. For Smoking Cessation
Term
TEA
Definition
Ganglionic Nicotinic Blocker.
Term
Trimethaphan
Definition
Ganglionic Nicotinic Blocker.
Term
Gallamine
Definition
NMJ Nicotinic Blocker.
Quat.
Term
Succinylcholine
Definition
NMJ Nicotinic Blocker.
Term
Tubocurarine
Definition
NMJ Nicotinic Blocker. (Natural)
Long-Acting
Term
Decamethonium
Definition
Depolarizing Nicotinic Blocker.
Term
Succinylcholine
Definition
Depolarizing Nicotinic Blocker.
Ultra-short acting
Term
Atracurium
Definition
Competitive Nicotinic Blocker.
Potency: Dox>Miv>Atra
Duration: Dox>Atra>Miva
Term
Doxacurium
Definition
Competitive Nicotinic Blocker.
Potency: Dox>Miv>Atra
Duration: Dox>Atra>Miva
Term
Mivacurium
Definition
Competitive Nicotinic Blocker.
Potency: Dox>Miv>Atra
Duration: Dox>Atra>Miva
Term
Pancuromium
Definition
Competitive Nicotinic Blocker.
Quat/Quat = Greater potency/duration
Elimination is more renal
Term
Pipecuronium
Definition
Competitive Nicotinic Blocker.
Quat/Quat = Greater potency/duration
Elimination is more renal
Term
Rapcuronium
Definition
Competitive Nicotinic Blocker.
Tert/Quat - Less Potency
Shortest duration
Term
Rocuronium
Definition
Competitive Nicotinic Blocker.
Tert/Quat - Less Potency
Duration: Pan/Pip>Roc/Vec>Rap
Term
Vecuronium
Definition
Competitive Nicotinic Blocker.
Tert/Quat - Less potency, but more than Rap/Roc
Term
2-PAM (Pyridine-2-Aldoxime Methiodide)
Definition
Antidote to Organophosphate Poisoning
Term
Hemicholinium
Definition
Choline uptake inhibitor
Term
Troxypyrrolidinum
Definition
Choline uptake inhibitor
Term
MNPV
Definition
ChAT inhibitor
Term
Alpha-latrotoxin (Spider venom)
Definition
Vesicular releaser of Ach
Term
Botulin
Definition
Blocks Ach release
Term
Vesamicol
Definition
Blocks Ach release
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