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Microbiology 22 [Unit-3]
Micro-22 [Unit 3] Set
4
Microbiology
Undergraduate 2
02/07/2011

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Term
Chemotherapy
Definition
treating disease (either infectuous or not) A term coined by Paul Ehrlich.
The basis of chemotherapy is selevtive toxicity, which means the chemical being used should inhibit or kill the intended pathogen w/o harming the host.
Term
Magic Bullet
Definition
a drug that can hunt down and destroy a pathogen w/o harming the infected host.
Term
Spectrum
Definition
a range of organisms affected by a drug.
- Broad = affects BOTH gram(+) and gram(-).
- Narrow = drug affects ONE or the other.
Term
Advantage and Disadvantage of Broad Spectrum (pro+con)
Definition
advantage = more likely to affect an unidentified pathogen
disadvantage = more damage to beneficial, normal flora; greater chance of ' superinfection' (or infection by 2nd pathogen and developmental resistance to drug)
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