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Micro Rx Clues
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142
Medical
Post-Graduate
12/14/2011

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Term
GRAY BABY SYNDROME
Definition
CHLORAMPHENICOL
Term
TX FOR SALMONELLA
Definition
CHLORAMPHENICOL
Term
MOA FOR CHLORAMPHENICOL
Definition
INHIBITS RIBOSOMAL PEPTIDYL TRANSFERASE
Term
POST INFLUENZA BACTERIAL PNEUMO WITH CAVITARY LESIONS
Definition
STAPH AUREUS - THIS IS WHAT KILLS OLD PPL AS THEY RECOVERING FROM INFLUENZA
Term
GRAM POSITIVE, CATALASE POSITIVE, COAGULASE POSITIVE COCCUS
Definition
STAPH AUREUS - TX WITH NAFCILLIN OR OXACILLIN
Term
PALMS N' SOLES RASH - SPIRLLAR PROKAYOTE WITH INTERNAL FLAGELLUM
Definition
2ND TREPONEMA PALLIDUM (SYPHILIS) - THIS SPROCHETE WITH ENDOFLAGELLA
Term
DRUG FOR PJP (AIDS PT)
Definition
TMP/SMX (TRIMETHAPRIM/SULFAMETHOXAZOLE
Term
RX FOR PATIENTS ALLERGIC TO TMP/SMX?
Definition
PENTAMIDINE
Term
RX FOR LEISHMANIA
Definition
MEGULMINE ANTIMONATE
Na STIBOGLUCONATE
Term
TREAT MAI WTITH? (CD COUNT <50)
Definition
AZITHROMYCIN
Term
BEST RX FOR C.DIFF COLITIS?
Definition
VANCOMYCIN
Term
CURRENT TX FOR C.DIFF COLITIS?
Definition
METRONIDAZOLE
Term
PREGNANT WOMEN'S RECTUM CLUTURE +VE FOR GROUP B STREP, RX WITH?
Definition
AMPICILLIN
Term
TREATMENT FOR HOOKWORMS
Definition
MEBENDAZOLE
THIABENDAZOLE
Term
TREATMENT FOR FLATWORMS
Definition
HYCLOSAMINE
NICLOSAMINE
Term
HOW DO HYCLOSAMINE N' NICLOSAMINE WORK?
Definition
PARALYZE THE WORM'S NERVOUS SYSTEM SO YOU POOP IT OUT
Term
WHAT RX TREAT MALARIA/
Definition
CHLOROQUINE (RESISTANCE) FOR PLASMODIUM
MEFLOROQUINE FOR PLASMODIUM + DOXYCYCLINE
PRIMAQUINE FOR VIVAX AND OVALE
QUININE + CLINDAMYCIN
Term
ONE DOSE TX FOR CANDIDIASIS?
Definition
FLUCONAZOLE (CANDIDA 'FLU' OUTTA CONTROL!"
Term
IMIDAZOLE THAT CROSSES BBB?
Definition
FLUCONAZOLE - GOOD B/C FUNGUS LOVE TO TRAVEL TO MENINGIS B/C THEY HAVE SUCH A FAT SOLUBLE STRUCTURE
Term
IMIDAZOLE THAT INHIBITS P450?
Definition
KETOCONAZOLE
Term
HOW TO YOU TX TINEA CAPITIS?
Definition
GRISEOFULVIN
Term
TREATMENT FOR LYME DISEASE?
Definition
PENICILLIN FIRST LINE** (CUZ ITS CHEAP)
TETRACYCLINES
Term
3 DRUGS THAT TREAT HERPES?
Definition
VALACYCLOVIR (BID) - BETTER COMPLIANCE
PENCICLOVIR (TID)
ACYCLOVIR (5X DAY) - YEAH THAT WASN'T TOO EFFECTIVE B/C OF COMPLIANCY ISSUES
Term
RX FOR CMV?
Definition
GANCYCLOVIR
Term
RX FOR SHINGLES
Definition
FAMCYCLOVIR - FAM - PAM - PAM HAD SHINLGES...EWWW
Term
RX FOR RSV
Definition
RIBAVARIN - R FOR RSV
Term
RX USED TO STOP VIRAL UNCOATING?
Definition
RAMANTADINE AND AMANTADINE
Term
HOW SOON TO ADMIN RAMANTADINE AND AMANTADINE SHOT AFTER EXPOSURE?
Definition
WITHIN 72HRS OF EXPOSURE WINDOW
Term
WHY DO WE PROPHYLAX CONTACTS OF PPL WITH INFLUENZA W/AMANTADINE FOR 2 WEEKS?
Definition
IgM TAKES 2WKS TO PEAK
IgG TAKES 3WKS TO FOLLOW UP
Term
SIDE EFFECT OF RAMANTADINE AND AMANTADINE
Definition
ANTICHOLINERGIC
Term
ANTI-CHOLINERGIC VS SYMPATHETIC DRUGS?
Definition
ANTICHOL WILL NOT ALLOW YOU TO SWEAT, BUT SYMP DRUGS WILL
Term
WHY IS AMANTADINE USED IN PARKINSON DISEASE?
Definition
PROMOTES DOPAMINE RELEASE AND ANTI-CHOL EFFECTS
Term
HOW DOES GRISEOFULVIN WORK?
Definition
INHIBITS MICROTUBULES LEADING TO INHIBITION OF FUNGAL REPLICATION (TINEA CAPITIS)
Term
HOW IS GRISEOFULVIN DELIEVERED?
Definition
INFECTED SITE, ON THE SKIN, TOPICALLY THROUGH THE SWEAT
Term
HOW DO THE IV/ORAL ANTIFUNGAL WORK?
Definition
BY INHIBITING SYNTHESIS OF EGOSTEROL
Term
TOPICAL (CREAMS) ANTIFUNGAL WORK BY/
Definition
BIND TO EGOSTEROL, DESTORY IT BY POKING HOLES IN IT
Term
WHICH ANTIFUNGAL IS PARENTERAL?
Definition
AMPHOTERICIN B, COULD BE SUPPOSITORY (ENTERAL)?
Term
HYPERKALEMIA + AMPHOTERICIN MEANS?
Definition
SYSTEMIC TOX DUE TO DESTRUCTION OF CHOLESTEROL IN THE CELL MEMBRANE LEADING TO LEAKING OF K+ INTO BLOODSTREAM
Term
HYPOKALEMIA + AMPHOTERICIN MEANS?
Definition
NEPHROTOX DUE TO DESTRUCTION OF THE CHOLESTEROL IN THE KIDNEY CELLS AND K+ LEAKS OUT IN URINE
Term
SIDE EFFECTS OF AMPHOTERICIN B
Definition
HYPOKALEMIA (RENAL), HYPERKALEMIA (ENDOTHELIAL), AND RENAL FAILURE
Term
2 FUNGAL INFECTIONS RX'D BY GRISEOFULVIN
Definition
TINEA CAPITIS AND TINEA VERSICOLOR
Term
LIST OF ATYPCALS ORGANISMS?
Definition
MYCOPLASMA, CHLAMYDIA, UREOPLASMA, LEGIONELLA
Term
SIMPLE GRAM -VE
Definition
E.COLI N' H.INFLUENZA
Term
MOA OF QUINALONES?
Definition
INHIBITS TOPOISOMERASES (DNA GYRASE - TOPO ii)
Term
COVERAGE OF QUINOLONES?
Definition
ALL GRAM +VE AND STAPH AURES, SIMPLE GRAM -VE, AND ATYPICALS
Term
NAME OF QUINOLONES?
Definition
CIPROFLOXACIN (GOOD FOR UREITIS, ABOVE BLADDER) - GATIFLOXACIN, OFLOFLOXACIN, NORFLOXACIN, and TROVOFLOXACIN
Term
WHICH QUINALONE GIVES YOU LIVER FAILURE?
Definition
TROVOFLOXACIN
Term
WHICH QUINOLONE IS MOST ACIDIC?
Definition
NORFLOXACIN
Term
MOA OF RIFAMPIN?
Definition
BLOCK BETA SUBUNIT OF RNA POLYMERASE
Term
COVERAGE OF RIFAMPIN?
Definition
TREATMENT FOR TB, PROPHYLAXIS OF INFLUENZA, PROPHYLAXIS OF NEISSERIA...EWWWW
Term
SIDE EFFECTS OF RIFAMPIN?
Definition
ORANGE SECRETIONS, REVS UP P450, HEPATITIS, AND MYOSITIS
Term
HOW SOON MUST YOU PROPHYLAX SOMEONE WITH RIFAMPIN AFTER CONTACT?
Definition
72 HRS
Term
MOA OF MACROLIDES?
Definition
INHIBITS 50S SUBUNIT BY INHIBITING TRANSLOCATION
Term
COVERAGE OF MACROLIDES
Definition
ALL GRAM +VE, STAPH AUREUS, SIMPLE GRAM -VE, ALL ATYPICALS
Term
SIDE EFFECTS OF MACROLIDES?
Definition
INHIBIT P450, GI UPSET, AND DYSGUSIA
Term
NAME THE MACROLIDES
Definition
ERTHROMYCIN, AZITHROMYCIN, CLARITHROMYCIN
Term
ANTIBIOTIC TREATMENT FOR MYCOBACTERIUM AVIUM INTRACELLULARE?
Definition
AZITHROMYCIN, CLARITHROMYCIN
Term
MACROLIDE WITH MOST DYSGUSIA?
Definition
CLARITHROMYCIN
Term
MACROLIDE WITH MOST GI UPSET?
Definition
ERTHYROMYCIN
Term
ONE DOSE TX FOR GONORRHEA?
Definition
CEFTRIAXONE 250MG IM - CEFIXIME - CEFOXETIN - CIPROFLOXACIN 500MG PO - GATIFLOXACIN 400MG PO - OFLOXACIN 400MG PO
Term
MOA OF CLINDAMYCIN
Definition
INHIBIT 50S SUBUNIT BY INHIBITING PEPTIDYLTRANSFERASE
Term
COVERAGE OF CLINDAMYCIN?
Definition
ALL GM + N' STAPH AUREUS, SIMPLE GRAM -VE and ANAEROBES***
Term
MCC OF PSUEDOMEMBRANOUS COLITIS?
Definition
Clindamycin
Term
MOA OF TETRACYCLINES?
Definition
INHIBIT 30S SUBUNIT BY INHIBITING tRNA*
Term
NAMES OF TETRACYCLINES?
Definition
T-MODD - MINOCYCLINE, OXYTETRACYCLINE, DOXYCYCLYINE, DAMECOCYCLINE
Term
COVERAGE OF TETRACYCLINES
Definition
ALL GRAM +VE, ALL ATYPICALS AND SIMPLE GRAM -VE -- MINUS*** StAPH AUREUS, & RICKETSIAL INFECTIONS***
Term
TETRACYCLINE THAT IS HEPATICALLY SECRETED?
Definition
DOXYCYCLINE
Term
TETRACYLINE THAT BLOCKS ADA RECEPTORS IN KIDNEY AND CAUSES NEPHROGENIC DI
Definition
DOMICOCYCLINE
Term
SIDE EFFECTS OF TETRACYCLINES
Definition
inducer of p450, GI UPSET, PILL ESOPHAGITIS, PHOTOSENSITIVTY, FANCONI SYNDROME (PCT FAIL, TYPE 2 RTA), BINDS CA+ IN GI, TURNS TEETH GRAY PERMANENTLY
Term
MOA OF PYRAMYCIN?
Definition
INHIBITS THE A SITE OF 50S SUBUNIT -- RIFAMPIN INHIBITED THE BETA SUBUNIT OF RNA POLYM
Term
MOA OF CHLORAMPHENICOL?
Definition
INHIBITS 50S SUBUNIT BY INHIBITING THE PEPTIDYL TRANSFERASE (LIKE CLINDAMYCIN)
Term
COVERAGE OF CHLORAMPHENICOL
Definition
STAPH AUREUS, GRAM +VE, RICKETSIAL INFECTION
Term
SIDE EFFECTS OF CHLORAMPHENICOL?
Definition
GRAY BABY SYNDROME, APLASTIC ANEMIA (part of hint ABCV - AZT, BENZENE, CHLORAMPHENICOL, AND VINCBLASTINE)
Term
HOW DOES CHLORAMPHENICOL CAUSE GRAY BABY SYNDROME?
Definition
INHIBIT's COMPLEX IV OF ELECTRON TRANSPORT CHAIN
Term
MOA OF AMINOGLYCOSIDES?
Definition
BLOCKS 30S SUBUNIT INHIBITING EF2
Term
WHAT DOES AMINOGLYCOSIDES COVER?
Definition
ALL GRAM NEGATIVES*****
Term
NAME THE AMINOGLYCOSIDES?
Definition
GASS Toll No Kash - GENTAMYCIN, AMIKACIN, STREPTOMYCIN, SPECTINOMYCIN, TOBRAMYCIN, NEOMYCIN, KENTAMYCIN
Term
AMINOGLYCOSIDE THAT IS HEPATICALLY SECRETED?
Definition
AMIKACIN
Term
AMINOGLYCOSIDES USED IN TRIPLE ANTIBIOTICS?
Definition
NEOMYCIN, POLYMYXIN B, and BACITRACIN
Term
AMINOGLYCOSIDE WITH MOST SIDE EFFECTS
Definition
GENTAMYCIN
Term
AMINOGLYCOSIDE USED TO TREAT TB
Definition
STREPTOMYCIN
Term
SIDE EFFECTS OF AMINOGLYCOSIDES?
Definition
OTOTOXICITY, NEPHRO AND NEUROTOXICITY
Term
HOW DO AMINOGLYCOSDIES CAUSE NEUROTOX?
Definition
INHIBIT THE PRESYNAPTIC INFLUX OF CALCIUM - SO CAN'T TRANSPORT NEUROTRANSMITTERS
Term
CAUSES OF DYSGUSIA
Definition
ZINC DEF, METRONIDAZLE, MACROLIDES
Term
WHICH DRUGS CAUSE NEPHROGENIC DI?
Definition
LITHIUM AND DAMICOCYCLINE
Term
WHICH PART OF TRIPLE ANTIBIOTIC OINTMENT IS RESPONSIBLE FOR THE RASH?
Definition
NEOMYCIN
Term
MOA OF VANCOMYCIN
Definition
INHIBITS CELL WALL SYNTHESIS BY INHIBITING THE PHOSPHOLIPID CARRIER*
Term
COVERAGE OF VANCOMYCIN?
Definition
GRAM +VE, STAPH AUREUS, ENTEROCOCCUS, AND STAPH EPIDERMITIS (SO IF YOU SEE QUES WITH CENTRAL LINE N' VEGETATIONS YOU PICK THIS!!! - DO NOT EVEN THINK ABOUT PICKING NAFICILLIN, DOXOCILLIN, COXICILLIN....AND THOSE FUCKERS
Term
SIDE EFFECTS OF VANCOMYCIN?
Definition
OTOTOXICITY, NEPHROTOXIC, AND RED MAN SYNDROME
Term
WHAT THE HELL IS RED MAN SYNDROME?
Definition
VANCOMYCIN SIDEEFFECT - INFUSION WAS DONE TOO FAST AND CAUSES HISTAMINE RELEASE
Term
MOA OF METRONIDAZOLE (FLAGYL)
Definition
CAUSES RELEASE OF FREE RADICALS - TOTALLY FUCK UP ANAEROBES!
Term
COVERAGE OF METRONIDAZOLE?
Definition
ALL ANAEROBES, GARDNERELLA, PROTOZOA
Term
SIDE EFFECTS OF METRONIDAZOLE?
Definition
DYSGUSIA, DISULFURAM RXN, G6PD (FREE RADICALS!), METHEMOGLOBINEMIA, AND HEMOLYTIC ANEMIA - FREE RADICALS (moa OF THIS DRUG) JUST FCKING SHIT UP!
Term
BIG MAMA DRUGS FOR ANAEROBES?!
Definition
METRONIDAZOLE, CLINDAMYCIN, CEFOXATIN
Term
HOW DO SULFA DRUGS WORK?
Definition
INHIBIT PABA! (STOPS DIHYDROPTEROATE SYNTHETASE -- TRIMETHOPRIM BLOCKS DIHYDROFOLATE REDUCTASE*)
Term
5 SULFA DRUGS?
Definition
SULFAMETHOXAZOLE
SULFADIAZINE
SULFAPYRIZONE
SULFACETMIDE
Term
2 DRUGS USED WITH SULFA DRUGS THAT BLOCK DIHYDROFLOATE REDUCTASE?
Definition
TRIMETHAPRIM AND PYRIMETHAMINE
Term
COVERAGE FOR SULFA RX?
Definition
GRAM +VE AND STAPH AUREUS AND SIMPLE GRAM -VE (USE FOR URETHRITIS - FOR E.COLI)
Term
TREATMENT FOR PCP AND UTI'S?
Definition
SMX/TMP - SULFAMETHOXAZOLE AND TRIMETHAPRIM
Term
SULFA DRUGS USED FOR BURN PATIENTS?
Definition
SULFADIAZINE (SILVADINE)
Term
SULFA DRUGS USED TO TREAT TOXOPLASMOSIS
Definition
SULFADIAZINE AND TRIMETHAPRIM - BURN (RX) TMP
Term
SULFA DRUGS THAT COMES IN AN EYE DROP?
Definition
SULFACETAMIDE (face!!)
Term
3 SULFA DRUGS THAT ARE USED TO TREAT ULCERATIVE COLITIS
Definition
#1 SULFASALAZINE
2/SULFAPRYIZONE
3/SULFACETAMIDE
Term
MOA OF PENICILLINS?
Definition
CELL WALL INHIBITOR BY INHIBITING TRANSPEPTIDATION - ATTACKS GARAGE DOOR IN STRUCTURE*
Term
COVERAGE FOR ALL PENICILLINS?
Definition
GRAM +VE not STAPH AURUES*** (PRETTY OBVIOUS NOW A DAYS) -- AND ALL SIMPLE ANAEROBES
Term
SIDE EFFECTS OF PENICLLIN?
Definition
ANAPHYAXIS, DRUG RASH***, INTERSTITIAL NEPHRITIS, AND HEMOLYTIC ANEMIA
Term
WHICH PENICILLIN IS ORALLY GIVEN?
Definition
PEN V
Term
WHICH PENICILLIN IS GIVEN IV?
Definition
PEN G
Term
TWO EXTENDED SPECTRUM PENICLLINS?
Definition
AMOXACILLIN and AMPICILLIN
Term
WHAT COVERAGE DO THE EXTENDED SPECTRUM PCN'S ADD?
Definition
SIMPLE GRAM -VE COVERAGE
Term
WHAT IS ADDED TO THE SIMPLE PCN'S TO COVER STAPH AUREUS
Definition
AMOXACILLIN/CLAUVULINIC ACID
AMOXACILLIN/SULBACTAM
Term
EXTENDED SPECTRUM PENICILLINS WHICH CAUSE JARISH-HERXEHEIMER REACTION?
Definition
EBV, CMV, SYPHILIS
Term
DRUG OF CHOICE FOR UTI DURING PREGNANCY?
Definition
AMPICILLIN/SULBACTUM

not CIPROFLOXACIN!!! - ITS OKAY IN NORMAL MALE/FEMALE BUT C'MON A TOPOISOMERASE INHIBITOR (QUINOLONE) IN PREG LADY IS BAD NEWS - B/C ITS FAT SOLUBLE N' FUCK UP FETUS LIVER!
Term
MC USED IN PEDIATRICS?
Definition
AMOXACILLIN (the pink stuff - believe it or not the taste is patented)
Term
5 ANTI-STAPH PCN'S (BETA-LACTAMASE RESISTANT)
Definition
METHACILLIN, NAFCILLIN, OXACILLIN, DICLOXICILLIN, CLOXACILLIN
Term
MCC OF INTERSTITIAL NEPHRITIS?
Definition
#1 METHACILLIN
2/AMPICILLIN
Term
3 NON-PSUEDOMONAL ANTI-STAPH PCN'S (ONLY STAPH)
Definition
PART OF CONDOM PNEUMONIC IN FIRST AID - KEYS ONE - OXACILLIN, DICLOXACILLIN, AND CLOXACILLIN
Term
IV ANTI-STAPH PCN?
Definition
NAFCILILN
Term
ANTI-STAPH PCN WITH A HIGH SODIUM LOAD?
Definition
NAFCILLIN - LINK WITH IV DELIVERY
Term
5 ANTI-PSEUDOMONAL PCN'S?
Definition
PSUEDO TAKES ALL MY CASH - PIPERCILLIN, TICARCILLIN, AZOCILLIN, MEZLOCILLIN, and CARBENICILLIN
Term
ANTI-PSEUDOMONAL PCN WITH HIGH SODIUM LOAD?
Definition
CARBENICILLIN - LIKE HIGH CARBS lol
Term
WHAT DRUGS ARE ADDED TO THE ANTI-PSEDUOMONAL PCN'S TO COVER STAPH?
Definition
PIPERCILLIN/TAZOBACTAM
TICARCILLIN/CLAUVULINIC ACID
Term
MOA OF CELPHALOSPORINS?
Definition
CELL WALL INHIBITOR BY INHIBITING TRANSPEPTIDATION
Term
COVERAGE FOR ALL CELPHALOSPORINS?
Definition
GRAM +VE, STAPH aURUES AND SIMPLE GRAM -VE
Term
1ST GENERATION CELPHALOSPORIN THAT IS PARENTERAL
Definition
CEFAZOLIN
Term
1ST GEN OF CELPHALOSPORINS THAT IS #1 CAUSE OF INTERSTITIAL NEPHRTIS?
Definition
CEPHALOTIN
Term
NAME FIVE 1ST GEN CEPHALOSPORINS?
Definition
CEFAZOLIN, CEFALOTIN, CEFALEXIN, CEFADOXIL, CEFADROXIL
Term
NAME FIVE 2ND GEN CELPHALOSPORINS?
Definition
CEFACLOR, CEFOTETAN, CEFOMANDOL, CEFUROXIME, CEFOXATIN
Term
NAME SIX 3RD GEN CEPHALOSPORINS?
Definition
CEFTRIAXONE, CEFIXIME, CEFOTAXIME, CEFTAZIDINE, CEFPERAZOME, MAXALACTAM
Term
MOST COMMONLY USED CEPHALOSPORIN USED IN KIDS?
Definition
CEFACLOR (2ND GEN)
Term
CEPHALOSPORIN USED TO TREAT H. INFLUENZA B?
Definition
CEFURXOIME (2ND GEN)
Term
CEPHALOSPORIN USED TO TREAT ANAEROBES?
Definition
CEFOXATIN (2ND GEN)
Term
CEPHALOSPORIN WITH THE BEST CNS PENETRATION?
Definition
CEFTRIAXONE - GOOD TO GO FIND GONNORRHEA...EWW (3RD GEN!)
Term
HEPATICALLY EXCRETED CEPHALOSPORIN?
Definition
CEFTRIAXONE (3RD GEN) GOT GREAT CNS PENETRATION
Term
FIRST LINE MENINGITIS <2mo OLD?
Definition
CEFOTAXIME
Term
FIRST LINE MENINGITIS >2mo OLD? (EVERYONE ELSE)
Definition
CEFTRIAXONE
Term
FIRST LINE PSEUDOMONAS?
Definition
CEFTAZIDINE
Term
FOUR CEPHALOSPORINS WITH MTT (methylthiotetrazole) SIDE CHAINS?
Definition
BAD SE - CAUSES COAGULOPATHY WITH VIT K INHIBITION** -- CEFOTETAN, CEFOMANDOL, CEFAPERAZONE, MOXALACTAM
Term
WHAT DOES methylthiotetrazole (MTT) CHAIN DO?
Definition
INHIBITS VIT K
Term
ONLY ORAL 3RD GEN CEPHALOSPORIN?
Definition
CEFIXEME
Term
CEFALOSPORIN WITH HIGHEST ALLERGIC REACTION IN PEDIATRICS?
Definition
CEFACLOR
Term
DRUGS THAT CAUSE DISULFURAM LIKE RXN?
Definition
CEFOTETAN, CEFOMANDOL, METRONIDAZOLE***
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