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Lorazepam
JSRCC Drugs
11
Medical
Undergraduate 1
09/09/2015

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Cards

Term
Lorazepam Generic Name
Definition
Lorazepam
Term
Lorazepam Trade Name
Definition
Ativan
Term
Lorazepam Class
Definition
Benzodiazepine
Term
Lorazepam Mechanism of Action
Definition
Binds to benzodiazepine receptors and enhances the effects of the inhibitory neurotransmitter GABA, causing anticonvulsant, anti-anxiety and amnesic effects
Term
Lorazepam Indications
Definition
Major motor seizures, skeletal muscle relaxant, status epilepticus, premedication prior to cardioversion, preprocedure sedation, acute anxiety stress, violence and/or agitation
Term
Lorazepam Contraindications
Definition
COPD, CNS depression, hypotension, shock, coma, acute closed-angle glaucoma
Term
Lorazepam Adverse Reactions
Definition
Hypotension, drowsiness, amnesia, respiratory depression, blurred vision, nausea, vomiting, syncope, paradoxical CNS stimulation
Term
Lorazepam Onset
Definition
20-30 min
Term
Lorazepam Duration
Definition
6-8 hours
Term
Lorazepam Dose
Definition
1-4 mg IV/IO over 2-5 min. Can be repeated in 10-15 min to a max dose of 8 mg per 12 hours
Term
Lorazepam Peds Dose
Definition
0.05-0.2 mg/kg slow IV/IO/IM over 2 min. May repeat once in 5 min,
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