Shared Flashcard Set

Details

Lipid lowering drugs
meh
6
Medical
Undergraduate 2
06/07/2011

Additional Medical Flashcards

 


 

Cards

Term
Statins (HMG-CoA reductase inhibitors)
Definition
Statins (HMG-CoA reductase inhibitors)

Simvastatin, Fluvastatin, Pravastatin, Atorvastatin

"HMG-CoA reductase inhibitors
* Inhibit LDL cholesterol production
* Cause a decrease of 20 – 50 % in serum LDL levels
* Reduce serum triglyceride levels"
Term
Fibrates
Definition
Fibrates

Gemfibrozil

"Acts as an agonist at a nuclear receptor (PPAR(alpha) or
peroxisome proliferator activated receptor)
Increases lipolysis (breakdown of lipids) in tissues
resulting in a decrease in LDL"
Term
Bile acid-binding resins
Definition
Bile acid-binding resins

Cholestyramine, Colestipol, Colesevelam

Anion exchange resins bind to bile acids in the intestine
Term
Nicotinic acid
Definition
Nicotinic acid

Niacin, vitamin B3

"Decreases lipoprotein synthesis in the liver resulting in
a decrease in LDL, and an increase in HDL"
Term
Ezetimibe
Definition
Ezetimibe

Zetia or Ezetrol

Inhibits absorption of cholesterol from the gastrointestinal tract and thereby decreases total cholesterol, triglycerides and LDL
Term
Fish Oils
Definition
Fish Oils

N/A

Decreases production of triglycerides, reduces blood clotting and inflammation
Supporting users have an ad free experience!