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Lecture 4: Mice, Rats, Hamsters
Intro to Animal Management
67
Science
Undergraduate 1
09/16/2013

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Term
Scientific name for Mouse
Definition
Mus musculus
Term
Scientific name for Rat
Definition
Rattus norvegicus
Term
Scientific name for Hamster
Definition
Mesocricetus auratus
Term
Strain
Definition
group of organisms of the same species that have a distinct characteristic but are not usually considered a separate breed or variety
Term
7 Mouse breeding system designations
Definition
(a) Random bred [=Outbred]
(i) Swiss mice, Balb/c, Db/Db,Ob/Ob
(b) Inbred
(c) F1 Hybrids
(i) Familiar generation 1
(d) Recombinant Inbreds [RI]
(e) Coisogenic Inbreds
(f) Congenic Inbreds
(g) Segregating inbreds
Term
Are Mice covered by the AWA?
Definition
No
Term
Are Rats covered by the AWA?
Definition
No
Term
Are Hamsters covered by the AWA?
Definition
Yes
Term
Conventional Facilities
Definition
no isolation or separation from outside sources
Term
Barrier Facilities
Definition
shower in & out of facility [sometimes use micro-isolator lids with HEPA filters
Term
HEPA
Definition
High Efficacy Particulate Air
Term
What kind of plastic?
Definition
Polycarbonate
Term
What kind of cage is most often used with Mice?
Definition
Shoebox
Term
What kind of cage is most often used with Rats?
Definition
Stainless steel more common
Term
What kind of cage is used with Hamsters? What special feature must it have?
Definition
Shoebox with locking lid
Term
How many Mice in a cage?
Definition
Groups but males barber
Term
How many Rats in a cage?
Definition
1-3, don't barber
Term
How many Hamsters in a cage?
Definition
Groups as young, 2-3 when adults
Term
Barbering
Definition
males mice fight, alpha beats on others, alpha isolated or put in new group, new male takes place, barbering starts again
Term
Neoplasia
Definition
formation of tumor or other abnormal cells [usually cancer]
Term
Mouse, Rat, and Hamster bedding
Definition
Depends on facility & research needs; corncob, pine, Tex Fresh
NO CEDER
Term
Hamster pellets must be where?
Definition
On floor of cage
Term
Mouse and Rat diet and how long it's good
Definition
Commercially prepared rodent chow, 3-5g pellets, only good for 6 months after mill date
Term
Temperature of Mouse and Rat enclosure
Definition
68-79 F,
Term
Humidity level of Mouse, Rat, and Hamster enclosure
Definition
30-70% humidity
Term
Temperature of Hamster enclosure
Definition
65-70 F
Term
At what temperature does mouse health fail over?
Definition
37 C
Term
Mouse bacterial diseases
Definition
(a) Staph, Corynebacterium, Pasteurella pneumotropica, Helicobacter- highly contagious, zoonotic [animal-person]
Term
Mouse viral diseases
Definition
(a) MHV- Mouse Hepatitis Virus- corona virus, highly contagious
(b) EDIM-Epizootic Diarrhea of Infant Mice- roto virus
(c) MPV- Mouse Parvo Virus
(d) LCM- Lymphocytic [kills lymphocytes] Choriomeningitis- cause Encephalitis [acute inflammation of brain] & Meningitis [acute inflammation of meninges [protective covers for spine & brain]]
Term
Mouse parasitic diseases
Definition
(i) Fur Mites- microscopically seen, from outside sources
(b) Pin Worms- nematodes- intestinal, larvae around butt [check with tape]
Term
Mouse non-infectious diseases
Definition
(a) Age related kidney & liver disease
(b) Skin legions
(c) Whisker & Tail eating
Term
Strain
Definition
group of organisms of the same species that have a distinct characteristic but are not usually considered a separate breed or variety
Term
7 Mouse breeding system designations
Definition
(a) Random bred [=Outbred]
(i) Swiss mice, Balb/c, Db/Db,Ob/Ob
(b) Inbred
(c) F1 Hybrids
(i) Familiar generation 1
(d) Recombinant Inbreds [RI]
(e) Coisogenic Inbreds
(f) Congenic Inbreds
(g) Segregating inbreds
Term
Are Mice covered by the AWA?
Definition
No
Term
Are Rats covered by the AWA?
Definition
No
Term
Are Hamsters covered by the AWA?
Definition
Yes
Term
Conventional Facilities
Definition
no isolation or separation from outside sources
Term
Barrier Facilities
Definition
shower in & out of facility [sometimes use micro-isolator lids with HEPA filters
Term
HEPA
Definition
High Efficacy Particulate Air
Term
What kind of plastic?
Definition
Polycarbonate
Term
What kind of cage is most often used with Mice?
Definition
Shoebox
Term
What kind of cage is most often used with Rats?
Definition
Stainless steel more common
Term
What kind of cage is used with Hamsters? What special feature must it have?
Definition
Shoebox with locking lid
Term
How many Mice in a cage?
Definition
Groups but males barber
Term
How many Rats in a cage?
Definition
1-3, don't barber
Term
How many Hamsters in a cage?
Definition
Groups as young, 2-3 when adults
Term
Barbering
Definition
males mice fight, alpha beats on others, alpha isolated or put in new group, new male takes place, barbering starts again
Term
Neoplasia
Definition
formation of tumor or other abnormal cells [usually cancer]
Term
Mouse, Rat, and Hamster bedding
Definition
Depends on facility & research needs; corncob, pine, Tex Fresh
NO CEDER
Term
Hamster pellets must be where?
Definition
On floor of cage
Term
Mouse and Rat diet and how long it's good
Definition
Commercially prepared rodent chow, 3-5g pellets, only good for 6 months after mill date
Term
Temperature of Mouse and Rat enclosure
Definition
68-79 F,
Term
Humidity level of Mouse, Rat, and Hamster enclosure
Definition
30-70% humidity
Term
Temperature of Hamster enclosure
Definition
65-70 F
Term
At what temperature does mouse health fail over?
Definition
37 C
Term
3 Rat nomenclatures and species
Definition
(1) Outbred
(a) Sprague-Dawley, Long-Evans
(2) Inbred
(a) Fischer, Lewis, Wistar-Kyoto
(3) Mutant
(a) Brattle-Boro- Diabetes Insipidous
(b) Gunn- Jaundice
Term
Can Rats vomit?
Definition
No
Term
Rat bacterial diseases
Definition
Klebsiella, Pasteurella pneumotropica, Helicobacter
Term
Rat viral diseases
Definition
Parvo
Term
What are Rats infamous for getting
Definition
Tumors
Term
4 major reasons Hamsters are used for research
Definition
(a) Availability & ease of reproduction [easy to make new ones]
(b) Relatively free from spontaneous diseases
(c) Anatomy & physiological reasons [cheek pouches, type 2 diabetes is hereditary]
(d) Because they develop rapidly and have short lifecycles, you see the disease move through their system quickly
Term
Where are Hamster scent glands?
Definition
Lumbar region
Term
Hamster bacterial diseases
Definition
E.coli
Campylobacter
Term
Hamster viral diseases
Definition
Parvo
LCM
Term
Hamster parasitic diseases
Definition
Protozoa [no disease or symptoms] …but not pathogenic
Term
Hamster non-infectious diseases
Definition
(a) Wet Tail- diarrhea
(b) Ileitis- inflammation of intestine
(c) Lympho Sarcoma- cause liver tumors
Term
Hamster neoplasia conditions
Definition
Urinary bladder & Pancreatic tumors
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