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L67 - Adrenergic agonists
Creighton University School of Medicine
40
Medical
Professional
05/05/2013

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Cards

Term
Term
Definition
Definition
Term
Epinephrine targets
Definition
This drug targets Alpha-1, Alpha-2, Beta-1, Beta-2, Beta-3 receptors
Term
Norepinephrine targets
Definition
This drug targets Alpha-1, Alpha-2, Beta-1 receptors
Term
Isoproterenol targets
Definition
This drug targets Beta-1, Beta-2, Beta-3 receptors
Term
Phenylephrine targets
Definition
This drug targets Alpha-1 receptors
Term
Oxymetazoline and Brimonidine targets
Definition
This drug targets Alpha-2 receptors in the peripheral nervous system
Term
Clonidine and Guanfacine targets
Definition
This drug targets Alpha-2 receptors in the CNS
Term
Dobutamine targets
Definition
This drug targets Beta-1 receptors
Term
Albuterol, Terbutaline, Salmetertol targets
Definition
This drug targets Beta-2 receptors
Term
Mirabegron targets
Definition
This drug targets Beta-3 receptors
Term
Epinephrine metabolism
Definition
This drug is metabolized by MAO and COMT (1)
Term
Norepinephrine metabolism
Definition
This drug is metabolized by MAO and COMT (2)
Term
Norepinephrine cardiovascular actions
Definition
This drug causes Decreased HR, Increased BP, Increased Peripheral Resistance (1)
Term
Phenylephrine cardiovascular actions
Definition
This drug causes Decreased HR, Increased BP, Increased Peripheral Resistance (2)
Term
Norepinephrine vs. Phenylephrine (magnitude of cardio response)
Definition
Phenylephrine causes a larger response than norepinephrine
Term
Isoproterenol cardiovascular actions
Definition
This drug causes Increased HR, Decreased mean/diastolic BP, Increased systolic BP, and Decreased Peripheral Resistance
Term
Drugs that stimulate release of norepinephrine from sympathetic nerves
Definition
Amphetamine, methamphetamine, Methylphenidate, phentermine, Tyramine
Term
Drugs that block neuronal uptake of norepinephrine
Definition
Tricyclic antidepressants (desipramine, Imipramine) and cocaine
Term
Mixed acting sympathomimetic drugs
Definition
ephedrine, Pseudoephedrine
Term
Tyramine + this drug is dangerous
Definition
This drug with Phenelzine, is dangerous
Term
Amphetamine MOA
Definition
This drug stimulates release of norepinephrine
Term
Phenelzine MOA
Definition
This drug blocks the action of MAO
Term
Cocaine MOA
Definition
This drug blocks reupate of norepinephrine
Term
Pseudoephrine MOA
Definition
This drug stimulates release of norepinephrine in addition to stimulating the adrenoceptors
Term
Drug for treating cardiac arrest
Definition
Epinephrine is helpful in treating
Term
Drug for treating cardiogenic shock
Definition
Dobutamine and Dopamine is helpful in treating
Term
Drug for treating arrhythmias
Definition
Phenylephrine is helpful in treating (1)
Term
Drug for treating hypotension
Definition
Phenylephrine is helpful in treating (2)
Term
Drug for treating bronchoconstriction
Definition
Albuterol is helpful in treating
Term
Drug for treating nasal congestion
Definition
Pseudoephedrine, Phenylephrine, Oxymatazoline is helpful in treating
Term
Drug for treating wide/open angle glaucoma
Definition
Epinephrine and Brimonidine is helpful in treating
Term
Drug for treating congestion in the eye
Definition
Tetrahydrozoline is helpful in treating
Term
Drug for treating overactive bladder
Definition
Mirabegron is helpful in treating
Term
Drug for treating ADHD
Definition
Amphetamine and Methylphenidate treat this by increasing dopamine and norepinephrine in prefrontal cortex
Term
Drug for treating obesity
Definition
Phentermine treats this by suppresing appetite by increasing norepinephrine, dopamine, and serotonin in the CNS
Term
Drug for treating depression
Definition
Tricyclic antidepressants (desipramine, Imipramine) treat this by blocking neuronal uptake of norepinephrine and/or serotonin in the CNS
Term
Cardiovascular adverse effects of sympathomimetics
Definition
Palpitations/tachycardia/ischemia/angina (beta-1 > beta-2 drugs), increased BP, and bradycardia from (alpha-1 and alpha-2 drugs)
Term
Genitourinary adverse effects of sympathomimetics
Definition
Urinary retention (from alpha-1 drugs)
Term
CNS adverse effects of sympathomimetics
Definition
Stimulation (indirect > mixed > direct acting drugs)
Term
Skeletal muscle adverse effects of sympathomimetics
Definition
Tremors (Beta-2 > Beta-1 drugs)
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