Shared Flashcard Set

Details

Invasive fungal infection
exam 2 study guide
9
Pharmacology
Graduate
02/25/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
What is the difference between filamentous molds and yeats?
Definition
Term
What are the three clinical circumstances in which plasma level monitoring of antifungal agents can be indicated?
Definition
Term
What is the difference between "aquired" & "intrinsic" resistance to fluconazole?
Definition

Intrinsic resistance: resistance recorded prior to drug exposure in vivo or in vitro

Acquired resistance: resistance that develops on exposure to antifungal 

Resistance mechanism: increased drug efflux, upregulation of ERG11, alteration in sterol composition, decreased azole binding due to mutation in ERG11

Term
What are fine species of Candida that are commonly encountered in the clinical setting?
Definition

C. albicans (most common for nosocomial fungal blood stream infection)

C. glabrata

Aspergillus

Trichosporon

Fusarium 

Term
What are treatment options for hematogenously disseminated candidiasis caused by Candida?
Definition
Term
What are treatment options for the treatment of invasive aspergillosis?
Definition
Term
What are common mechanisms of drug interactions with azole antifungal?
Definition
Term
What are common ADE of various formulations of amphotericin B?
Definition
Supporting users have an ad free experience!