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INTEGUMENTARY SYSTEM-I
Pathology of skin infections
49
Medical
Kindergarten
07/31/2012

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Term
Complex organ weighing an average 4kg covering an area sq m.
Definition
skin
Term
Protects against harmful agents, microorganisms, physical, ultraviolet light. Regulates temperature and also plays a role in immune regulation through skin associated lymphoid tissue
Definition
skin
Term
epidermis consists of 4 layers from surface to base
Definition
Stratum corneum, stratum granulosum, stratum spinosum, and basal layer
Term
4 cell types found in the epidermis
Definition
keratinocytes, basal cells, melanocytes, Langerhan cells
Term
Between the epidermis and dermis
Definition
Basement membrane zone
Term
tough, elastic support, contains blood vessels, nerves and skin appendages
Definition
dermis
Term
sweat glands, hair follicles, sebaceous glands
Definition
skin appendages
Term
lies between the dermis and fascia. insulates the body, cushions deep tissues from blunt trauma
Definition
subcutaneous fat
Term
which cell makes up the majority of epidermal cells
Definition
keratinocytes
Term
source of cytokines that regulate cutaneous environment
Definition
squamous cells
Term
produce melanin pigment to screen uv light
Definition
melanocytes
Term
dendritic cells they are APCs to immune system
Definition
Langerhan cells
Term
detect pain and temp
Definition
Neural end organs
Term
part of skin which is used for cooling
Definition
sweat glands
Term
Verrucae is an epidermal hyperplasia caused by
Definition
HPV
Term
Transmission of Verrucae
Definition
Direct contact, or autoninoculation
Term
common wart, occur anywhere on the skin but mostly on the dorsum of the hand and fingers. Gray white papules
Definition
Verruca vulgaris
Term
flat wart, smooth slightly elevated papules, often occurs on face
Definition
verruca plana
Term
Scaly lesions 1-2 cm on soles and palms respectively
Definition
verruca plantaris and verruca palmaris
Term
soft, tan, cauliflower like papillomas on genitalia and perianal areas
Definition
conyloma acuminatum
Term
Morphology of conyloma accuminatum
Definition
1. Koilocytosis (cytoplasmic vacuolization) of superficial keratinocytes
2. Acanthosis, hyperkeratosis, and parakeratosis
3. viral particles within nuclei
Term
types 6 and 11 warts cause
Definition
anogenital warts
Term
type 16 warts cause
Definition
oncogenic
Term
Verrucae are treated by
Definition
self-limiting
Term
Papular skin lesions transmitted by direct contact in children and sexual active adults
Definition
Molluscum Contagiosum
Term
multiple pink umbilicated papules on skin and mucous membranes; cheesy material can be expressed from cup- like central umbilications
Definition
MC
Term
cup like hyperplasia of epidermal cells with large homogenous ellipsoid eosinophilic cytoplasmic inclusions.
Definition
MC
Term
Superficial skin infection caused by staph and strep usually on face and hands
Definition
Impetigo
Term
Erythematous macule - pustule - brk down to form crusts
Definition
Impetigo
Term
pustules contain neutrophils and gram + cocci
Definition
Impetigo
Term
Pus filled nodule in DERMIS usually caused by S. aureaus, ruptures through epidermis
Definition
Faruncle
Term
necrotizing infection of skin and subcutaneous tissue, composed of furuncles and also deeper
Definition
Carbuncle
Term
Erythematous swelling of the skin mainly caused by S. pyogenes. Common in warm climates
Definition
Erysipelis
Term
acute spreading infection of loose CT of deep layers of dermis. Usually through tramatic inoculation
Definition
Strep Cellulitis
Term
Superficial fungal infections are confined to what layer of epidermis
Definition
Stratum corneum
Term
erythematous sealing and maceration btw and underneath toes
Definition
Tinea pedis (athlete's foot)
Term
dermatophytosis of nail of fingers and toes causing deformity of nail plate
Definition
Onychomycosis
Term
Infection of scalp, affecting hair which tends to brk off.
Definition
Tinea capitis
Term
Infection of bearded regions
Definition
Tinea Barbae
Term
Infection of body, especially in children, expanding erythematous plaque with elevated scaling border
Definition
Tinea corporis
Term
Infection by malassezia furfur, affects trunk producing hyper-hypo macules with peripheral scaling (NICK)
Definition
Tinea versicolor
Term
a contagious skin caused by itch mites, burrows into stratum corneum mainly into skin of palms, wrist, scrotal folds, and periareolar skin. Intense itching and eczema
Definition
Scabies
Term
Infestation of lice usually on scalp or pubic area. May cause impetigo and cervical lymphadenopathy
Definition
Pediculosis
Term
Dermal perivascular infiltration with lymphocytes, eosinophils, and histiocytes
Definition
Arthropod bites
Term
With this disease almost all patients develop some sorts of skin disease
Definition
AIDS
Term
Microscopic appearance of intranuclear and intracytoplasmic nuclear inclusions, ulceration and intraepidermal acantholytic vessicles
Definition
HSV
Term
Occorence of this in an otherwise healthy person under age 60 is strong evidence of AIDS
Definition
Kaposi sarcoma
Term
other skin pathologies of AIDS
Definition
Purpura, pigmentation, major oral apththae
Term
HSV, scabies, deep mycoses, candidosis are found in
Definition
AIDS
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