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First Aid Pharm Drug Reactions
Drug Reactions
42
Medical
Graduate
04/07/2011

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Cards

Term
Atropine-Like side effects
Definition
TCAs (block reuptake)
Term
Coronary vasospasm
Definition
Cocaine (blocks reuptake), sumatriptan (5HT agonist)
Term
Cutaneous flushing
Definition
VANC: Vancomycin, Adenosine, Niacin, CCBs
Term
Dilated Cardiomyopathy
Definition
Doxorubicin (Adriamycin), daunorubicin
Term
Torsades de pointes
Definition
Class III and class IA antiarrhythmics
Term
Agranulocytosis
Definition
Clozapine, carbamazepine, colchicine, propylthiouracil, methimazole, dapsone
Term
Aplastic anemia
Definition
Chloramphenicol, benzene, NSAIDs, propylthiouracil, methimazole
Term
Direct Coombs-positive hemolytic anemia
Definition
Methyldopa (alpha-2 agonist and blocks dopa decarboxylase)
Term
Gray baby syndrome
Definition
Chloramphenicol
Term
Hemolysis in G6PD-def pts
Definition
Hemolysis IS PAIN
Isoniazid, sulfonamides, primaquine, aspirin, ibuprofen, nitrofurantoin
Term
Megaloblastic Anemia
Definition
Phenytoin (causes decreased folic acid), Methotrexate, Sulfa drugs
Having a BLAST w/ PMS
Term
Thrombotic Complications
Definition
OPCs (estrogens and progestins)
Term
Cough
Definition
ACEi's (NOT ARBs)
Term
Pulmonary Fibrosis
Definition
It's hard to BLAB w/ pulm fibrosis
BLeomycin, Amiodarone, Busulfan (alkylating agent)
Term
Acute Cholestatic hepatitis
Definition
Macrolides
Term
Focal to massive hepatitis
Definition
Halothane, valproic acid, acetaminophen, Amanita phalloides
Term
Hepatitis
Definition
Isoniazid
Term
Pseudomembranous Colitis
Definition
Clindamycin, ampicillin
Term
Adrenocortical insufficiency
Definition
Glucocorticoid withdrawal (HPA suppression)
Term
Gynecomastia
Definition
Some Drugs Create Awesome Knockers
Spironolactone, Digitalis, Cimetidine, Alcohol, estrogens, Ketoconazole
Term
Hot Flashes
Definition
Tamoxifen, clomiphene
Term
Hypothyroidism
Definition
Lithium, amiodarone
Term
Gingival Hyperplasia
Definition
Phenytoin
Term
Gout
Definition
Furosemide, thiazides, Niacin
Term
Osteoporosis
Definition
Corticosteroids, heparin
Term
Photosensitivity
Definition
SAT for a photo
Sulfonamides, Amiodarone, Tetracycline
Term
Rash (Steven-Johnson syndrome)
Definition
Ethosuximide, lamotrigine, carbamazepine, phenobarbital, phenytoin, sulfa drugs, penicillin, allopurinol
Term
SLE-like syndrome
Definition
Hydralazine, INH, Procainamide, Phenytoin
It's not HIPP to have lupus
Term
Tendonitis, tendon rupture, and cartilage damage (kids)
Definition
Fluoroquinolones
Term
Fanconi's syndrome (loss of function of proximal tubule)
Definition
Expired tetracycline
Term
Interstitial Nephritis
Definition
Methicillin, NSAIDs, furosemide
Term
Hemorrhagic Cystitis
Definition
Cyclophosphamide, ifosfamide (prevent by coadministering w/ mesna --> detox's metabolites w/ sulfa groups)
Term
Cinchonism
Definition
Quinidine, quinine
Term
Diabetes Insipidus
Definition
Lithium, demeclocycline (a tetracycline)
Term
Parkinson-Like Syndrome
Definition
Haloperidol, chlorpromazine, reserpine, metoclopramide
Term
Seizures
Definition
Bupropion, imipenem/cilastatin, isoniazid
Term
Tardive dyskinesia (involuntary, repetitive body movements)
Definition
Antipsychotics (increased dopamine effect)
Term
Disulfiram-like reaction
Definition
Metronidazole, certain cephalosporins, procarbazine, 1st-gen sulfonylureas
Term
Nephrotoxicity/Neurotoxicity
Definition
Polymyxins
Term
Nephrotoxicity/Ototoxicity
Definition
Aminoglycosides, vancomycin, loop diuretics, cisplatin
Term
P450 Inducers
Definition
Queen Barb Steals Phen-phen and Refuses Greasy Carbs CHRONICally
Quinidine, Barbiturates, St. Johns Wort, Phenytoin, Rifampin, Griseofulvin, Carbamazepine, CHRONIC alcohol use
Term
P450 Inhibitors
Definition
INHIBIT yourself from drinking beer from a KEG because it makes you ACUTEly SICk
HIV protease INHIBITORS, ketoconazole, erythromycin, grapefruit juice, acute alcohol use, sulfonamides, isoniazid, cimetidine
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