Term
| when is perinatal period? |
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Definition
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28 completed weeks of pregers to the 7th completed day after birth
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Term
| what are categories of perinatal death? |
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Definition
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Consequence of pre-term birth;
Disorders of utero-placental circulation;
Infection;
Developmental anomalies;
Specific disorders;
Unexplained
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Term
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Definition
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organs are immature, and therefore unable to adapt readily to extrauterine life. Although most preterm neonates have a low birth weight, not all lowbirth weight infants are preterm.
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Term
| why else can low birth weight occur? |
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Definition
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failure of the fetus to grow appropriately during gestion (fetal growth restriction)--so low birthweight babies can be born to term!!
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Term
| what ar causes for intrauterine growth retardation? |
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Definition
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Chromosomal disorders and developmental anomalies
Fetal infections
Disorders of utero-placental circulation
Maternal malnutrition and diseases
Drugs
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Term
| what are the complications of prematurity? |
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Definition
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1. Respiratory Distress Syndrome
2. Intraventricular Hemorrhage
3. Necrotizing Enterocolitis
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Term
| what is the acute phase of respiratory distress syndrome? |
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Definition
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Term
| what is the chronic phase? |
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Definition
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bronchopulmonary dysplasia
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Term
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Definition
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Difficult breathing within 30’ after birth
Clinical course depends on degree of prematurity and therapy employed
Hypoxemia, hypercarbia and metabolic acidosis
Chracteristic chest x-ray
(ground glass picture) intesne vascular congestion, necrosis of epithelial lining of distal airways, alternating atelectasis (collapse of previously inflated lung) and dialated respiratory brochioles lined by pink hyaline membranes
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Term
| hyaline membrane disease path? |
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Definition
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Epithelial necrosis;
Pulmonary congestion and edema;
Alternating atelectasis and dilated ;respiratory bronchioles;
Hyaline membranes
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Term
| bronchopulmonary dysplasia |
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Definition
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abnormal growth of the lung. Persistence of respiratory distress for up to 3 to 6 months or more
Abnormal lung growth that follows acute lung injury.
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Term
| bronchopulmonary dysplasia pathology? |
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Definition
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Alternating areas of overinflation and collapse
Interstitial fibrosis
Epithelial regeneration with squamous metaplasia in conducting airways
Abnormal vascular and alveolar development (“new” BPD)
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Term
| intraventricular hemorrhage |
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Definition
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Subependymal germinal matrix vasculature
Pressure/flow changes and hypoxia
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Term
| necrotizing enterocolitis |
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Definition
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Coagulation necrosis and inflammation;
Terminal ileum, cecum and ascending colon;
Preterm neonates
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Term
| complications of necrotizing enterocolitis? |
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Definition
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Early:
Perforation
Peritonitis
Sepsis and shock
Late:
Strictures
Short bowel syndrome
Malabsortion
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