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Title: fetal/perinatal path

Description: 5.1.07

Total Flash Cards: 15

Created: 05/01/2007 17:23:26

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Cards

Term
when is perinatal period?
Definition
28 completed weeks of pregers to the 7th completed day after birth
Term
what are categories of perinatal death?
Definition
Consequence of pre-term birth; Disorders of utero-placental circulation; Infection; Developmental anomalies; Specific disorders; Unexplained
Term
why are premmies ill?
Definition
organs are immature, and therefore unable to adapt readily to extrauterine life. Although most preterm neonates have a low birth weight, not all lowbirth weight infants are preterm.
Term
why else can low birth weight occur?
Definition
failure of the fetus to grow appropriately during gestion (fetal growth restriction)--so low birthweight babies can be born to term!!
Term
what ar causes for intrauterine growth retardation?
Definition
Chromosomal disorders and developmental anomalies Fetal infections Disorders of utero-placental circulation Maternal malnutrition and diseases Drugs
Term
what are the complications of prematurity?
Definition
1. Respiratory Distress Syndrome 2. Intraventricular Hemorrhage 3. Necrotizing Enterocolitis
Term
what is the acute phase of respiratory distress syndrome?
Definition
haline membrane disease
Term
what is the chronic phase?
Definition
bronchopulmonary dysplasia
Term
hyaline membrane disease
Definition
Difficult breathing within 30’ after birth Clinical course depends on degree of prematurity and therapy employed Hypoxemia, hypercarbia and metabolic acidosis Chracteristic chest x-ray (ground glass picture) intesne vascular congestion, necrosis of epithelial lining of distal airways, alternating atelectasis (collapse of previously inflated lung) and dialated respiratory brochioles lined by pink hyaline membranes
Term
hyaline membrane disease path?
Definition
Epithelial necrosis; Pulmonary congestion and edema; Alternating atelectasis and dilated ;respiratory bronchioles; Hyaline membranes
Term
bronchopulmonary dysplasia
Definition
abnormal growth of the lung. Persistence of respiratory distress for up to 3 to 6 months or more Abnormal lung growth that follows acute lung injury.
Term
bronchopulmonary dysplasia pathology?
Definition
Alternating areas of overinflation and collapse Interstitial fibrosis Epithelial regeneration with squamous metaplasia in conducting airways Abnormal vascular and alveolar development (“new” BPD)
Term
intraventricular hemorrhage
Definition
Subependymal germinal matrix vasculature Pressure/flow changes and hypoxia
Term
necrotizing enterocolitis
Definition
Coagulation necrosis and inflammation; Terminal ileum, cecum and ascending colon; Preterm neonates
Term
complications of necrotizing enterocolitis?
Definition
Early: Perforation Peritonitis Sepsis and shock Late: Strictures Short bowel syndrome Malabsortion



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