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Exam IV
Bio229 Ch18 -22
5
Microbiology
Undergraduate 1
05/16/2014

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Term
hypersensitivity
Definition
any immune response against a foreign antigen that is exaggerated beyond the norm
Term
type I hypersensitivity
Definition
localized or systemic reactions that result from the release of inflammatory molecules (ie, histamine) in response to an antigen. these reactions are termed immediate hypersensitivity because they develop within sec or min following contact with antigen. commonly called allergies. 2 parts- sensitization and degranulation.
Term
allergies
Definition
an immediate hypersensitivity response against an antigen
Term
allergen
Definition
an antigen that stimulates an allergic response
Term
sensitization of type I hypersensitivity
Definition
following initial exposure to allergens, the plasma cells of allergic individuals secrete IgE, which binds very strongly with its stem to 3 types of defense cells- mast cells, basophils, and eosinophils- sensitizing these cells to respond to future exposures to the allergen
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