Shared Flashcard Set

Details

Exam 2
Virology
19
Microbiology
Undergraduate 2
09/10/2009

Additional Microbiology Flashcards

 


 

Cards

Term
Viruses
Definition

Pirates of host cell functions

Obligate intracellular parasites

no ribosomes, membranes or organelles

requires electron mircroscope

Term
Viral Structure
Definition

have either DNA or RNA

some have lipid envelope

protein coat, capsid, is composed of capsomere subunits

Term
Virus Shape
Definition
Isometric, helical, or irregular
Term
Bacteriophages
Definition
bacterial viruses
Term
Infections due to animal viruses-clinical
Definition

asymptomatic

respiratory, GI, skin

acute or persistent

Term
Acute
Definition

rapid onset, short duration

virus is eradicated by host defenses

Term
Persistent
Definition

lasts years

balanced pathogenicity

infected carriers can transmit

latent, chronic, slow

Term
DNA viruses
Definition

small pox

herpes simplex

varicella-zoster (chicken pox, shingles)

epstein-barr (infectious mononucleosis)

hepatitis B

HPV

Term
RNA viruses
Definition

poliovirus

influenza

Hepatitis A and C

rhinoviruses (common cold)

coronaviruses (colds, SARS)

human immunodeficiency virus (HIV)

Term
multiplication of viruses
Definition

host cell becomes a plant for manufacture of new viruses

 

infection of a host cell with one virus can result in the release of thousands of viruses within a period of hours or days

Term

multiplication of animal viruses:

stages in "life" cycle

Definition

1. attachment

2. penetration/entry

3. targeting replication site

4. uncoating

5. biosynthesis of viral components

6. maturation/assembly

7. release from cell

8. spreading and shedding

9. transmission to new host

Term
Lytic/productive infection
Definition

virus multiplies and produces lots of virus

 

often kills/lyses host cell

Term
lysogenic infection
Definition

virus doesn't cause lysis/death of host cell

 

can replicate as a plasmid or viral DNA becomes a part of the chromosome = provirus

Term
Receptors on host cells
Definition

on the surface

specifically bind to molecules in environment

presence varies with tissue

Term
animal virus penetration
Definition

endocytosis or fusion

 

fusion: viral envolope fuses with the animal cell plasma membrane

Term
Targeting
Definition
the virus moves to the site of replication (cytoplasm, nucleus)
Term
Uncoating
Definition
the nucleic acid is released from the capsid
Term
biosynthesis
Definition

replication of the viral genome

production of viral proteins

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