Shared Flashcard Set

Details

Exam 1
Actually study these.
52
Nursing
Undergraduate 3
09/17/2012

Additional Nursing Flashcards

 


 

Cards

Term
debulk
Definition
remove as much of tumor as possiblevia surgery, making chemo and radiation more effective
Term
external beam
Definition
radiation therapy, markings placed on skin to calibrate radiation machine
Term
whats worse? Dry or Wet desquamation
Definition
Wet. Sloughing of skin. Keep area clean and protected and avoid constricting clothes
Term
When and Why does fatigue result during radiation?
Definition
3-4 weeks. Result of accumulation of metabolites from cellular destruction. Walking program intervention. EBP
Term
Factors that determine chemotherapy response
Definition
location, mitotic rate, size and age of tumor. more rapid = better response smaller = better response younger = greater response
Term
Which drug(s) are cell cycle non specific?
Definition
Cyclophosphaminde (Cytoxan) & Doxorubicin(Adriamycin)
Term
Which drug(s) are cell cycle specific?
Definition
Fluorouracil (5FU) & Vincristine (Oncovin)
Term
What class is Cyclophosphamide (Cytotoxan)?
Definition
Alkylating agent. May cause a 2nd malignancy. cell cycle non specific
Term
What class is Flourouracil (5FU)?
Definition
Antimetabolite. Cell Cycle specific and works on the S phase.
Term
What class is Doxorubicin (Adriamycin)?
Definition
Antitumor antibiotic. Cell Cycle non specific
Term
What class is Vincristine (oncovin)?
Definition
Mitotic inhibitor. Cell cycle specific and works on the M phase.
Term
What are the side effects of Cyclophosphamide (Cytotoxan)?
Definition
hemorrhagic cystitis N&V, myelosuppression, alopecia & hemorrhagic cystitis - permanent bladder destruction.
Term
What are the side effects of Flourouracil (5FU)?
Definition
stomatitis, diarrhea, N&V, myelosuppression, hyperpigmentation, hand-foot syndrome.
stomatitis - mouth sores
Term
What are the side effects of Doxorubicin (Adriamycin)?
Definition
Cariac toxicity, vesicant, myelosuppression, alopecia, N&V.
Cardiac toxicity - remember ejection fraction
Term
What are the side effects of Vincristine (oncovin)?
Definition
Neurotoxicities, constipation, Vesicant, parasthesia, foot drop, mild myelosuppression.
VinCristiNe (vessicant,constipation,neurotoxicity)
Term
What are nursing implications for Cyclophosphamide (Cytotoxan)?
Definition
Increase fluid intake, give early in the day, void frequently.
Term
What are nursing implications for Flourouracil (5FU)?
Definition
monitor mouth and bowel patterns, keep out of the sun, use sunscreen.
Term
What are nursing implications for Doxorubicin (Adriamycin)?
Definition
Need ejection fractions before given, first void will have pink urine due to red nature of drug. Also - vesicant.
Term
What are nursing implications for Vincristine (oncovin)?
Definition
Need bowel protocol (monitor constipation), Assess for peripheral neuropathy symptoms. Also- vesicant.
Term
Why is chemotherapy given through a central line?
Definition
Because Vesicant drugs can destroy tissues if they get out of the vessel.
Term
What is biotherapy?
Definition
boosting the immune system to better deal with cancer.
Term
What two types of biotherapy are there?
Definition
Alpha interferon & Interleukin - Aldesleukin (Proleukin)
Term
What are side effects of biotherapy?
Definition
flu-like effects. Acetaminophen before tx and q4h after tx. IV meperidine (demerol) to control severe chills, Vital signs, rest, adequate oral intake.
Term
What is targeted therapy?
Definition
Interferes w/ CA growth by targeting specific cellular receptors and pathways important for tumor growth. Able to kill tumor cells w/ less dmg. to normal cells.
Term
Rituximab (Rituxin) function
Definition
bind to CD 20; used with non-Hodgkin's lymphoma. Caoable of binding to target cells and destroying them. (TARGETED THERAPY)
Term
Rituximab (Rituxin) side-effects
Definition
flu like sx, BM suppression, fatigue, cardiotoxicity, hepatotoxicity, diarrhea, risk of anaphylaxis
Term
Class II Antidysrhythmic
Definition
Beta-Blockers- Check BP and HR. Hold <60 HR. 'olol SE: Bradycardia, Hypotension
Term
Class III Antidysrhythmic
Definition
Potassium Channel Blockers- Amiodarone, Sotalol
Term
Class IV Antidysrhythmic
Definition
Calcium Channel Blockers - Diltiazam - Decreases HR and BP. SE: Bradycardia, Hypotension
Term
Adenosine
Definition
Used to treat TACHYCARDIA, slows down the SA node
Term
Atropine
Definition
Used to treat BRADYCARDIA, speeds up the heart! SE: dilation of the pupils
Term
5 lead EKG (rhythm strip)
Definition
Just to show electro activity in the heart.
Term
12 lead EKG
Definition
ischemia or infarction? electrolyte imbalances? irregular positioning of heart?
Term
EKG paper 1 small box
Definition
0.04 seconds
Term
How many small boxes in one large box in an EKG?
Definition
5
Term
Angiogenesis inhibitor
Definition
bevacizumab (Avastin)
Term
Angiogenesis inhibitor function
Definition
VEGF- binds to vascular endothelial growth factor. VEGF
Term
Angiogenesis inhibitor side effects
Definition
HTN, colon bleeding & perforation, impaired wound healing, thromboembolism, hemorrhage. ALL BLEEDING RELATED STUFF
Term
What does Trastuzumab (Herceptin) do?
Definition
Binds to HER-2 & inhibits growth of breast cancer cells that overexpress the HER-2 protein.
Term
What herbs can interfere with CA treatment?
Definition
St. John's Wart, garlic, Echinacea
Term
Class IA,IB,IC Antidysrithmics
Definition
Sodium Channel Blockers Lidocaine, Procainimide, Quinidine
Term
How long is one large box on an EKG strip?
Definition
0.20 seconds
Term
What does the P wave represent?
Definition
Atrial depolarization
Term
What does the P wave represent?
Definition
Atrial depolarization
Term
What does the QRS complex represent?
Definition
Ventricular depolarization
Term
What does the T wave represent?
Definition
Ventricular repolarization
Term
PR interval length
Definition
0.12 - 0.20 seconds
(3-5 small boxes)
Term
QRS complex length (s)
Definition
Less than or equal to .11 seconds
(<3 small boxes)
Term
ST segment length
Definition
.12 seconds (3 little boxes)
Term
T wave length
Definition
.16 or 4 small boxes
Term
QT interval in length
Definition
.34 - .43 seconds
Term
How do you treat symptomatic bradycardia?
Definition
Atropine
Supporting users have an ad free experience!