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Drugs
j
79
Pharmacology
Pre-School
10/08/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
acetylcholine
Definition
direct musc agonist
glaucoma
Term
carbachol
Definition
direct musc agonist
glaucoma
Term
methacholine
Definition
direct musc agonist
asthma pulmonary testing
muscarinic sepcific
Term
bethanechol
Definition
direct musc agonist
promote GI motility
treat urinary retention
Term
pilocarpine
Definition
direct musc agonist
glaucoma
salivary gland
Term
endrophonium
Definition
reversible cholinesterase inhibitor
dx myasthenia gravis
Term
physostigmine
Definition
reversible cholinesterase inhibitor
treat atropine poisoning
reverse neuromuscular blockade
Term
neostigmine
Definition
reversible cholinesterase inhibitor
treat myasthenia gravis
reverse neuromuscular blockade
Term
pyridostigmine
Definition
reversible cholinesterase inhibitor
treat myasthenia gravis
used in military for pre-exposure
Term
rivastigmine
Definition
reversible cholinesterase inhibitor
treat alzheimers
Term
donepezil
Definition
reversible cholinesterase inhibitor
treat alzheimers
Term
carbamate
Definition
reversible cholinesterase inhibitor
Term
Parathion
Definition
irreversible cholinesterase inhibitor
Term
sarin
Definition
irreversible cholinesterase inhibitor
Term
sildenafil
Definition
cGMP phosphodiesterase inhib
erectile dysfunction - PDE - 5
Term
pralidoxine
Definition
cholinesterase reactivator
Term
atropine
Definition
muscarinic antagonist / anticholinergic
treat cholinesterase inhibitor poisoning
treat parathion poisoning
Term
scopolamine
Definition
muscarinic antagonist / anticholinergic
prevention of motion sickness
Term
dicyclomine
Definition
muscarinic antagonist / anticholinergic
irritable bowel syndrome
Term
propantheline
Definition
muscarinic antagonist / anticholinergic
irritable bowel syndrome
Term
glycopyrrolate
Definition
muscarinic antagonist / anticholinergic
pre-op to dry secretions and inhibit vagal reflexes
Term
ipratropium
Definition
muscarinic antagonist / anticholinergic
asthma, COPD
Term
benztropine
Definition
muscarinic antagonist / anticholinergic
parkinsons
Term
trihexyphenidyl
Definition
muscarinic antagonist / anticholinergic
parkinsons
Term
oxybutynin
Definition
muscarinic antagonist / anticholinergic
incontinence
Term
solifenacin
Definition
muscarinic antagonist / anticholinergic
incontinence
Term
tropicamide
Definition
muscarinic antagonist / anticholinergic
dilate pupil for opthalmic exam
Term
tolterodine
Definition
antimuscarinic / anticholinergic
incontinence
Term
pancuronium
Definition
neuromuscular blocking drug - competative
ach antagonist produces musc relaxation
Term
succinylcholine
Definition
depolorizing agent
cannot be overcome by cholinesterase inhibitors
Term
epinephrine
Definition
sympathomimetic - non selective
anaphylactic shock
asthma
cardiac arrest
bradycardia
circulatory shock
Term
NE
Definition
sympathomimetic - non selective
stim all except B2
neurogenic shock, septic shock, support of BP during spinal anesthesia
increase blood pressure and dec HR
Term
Isoproterenol
Definition
sympathomimetic - non selective
only stimulates beta
dec BP, inc HR
asthma, tilt test for syncopies
Term
dopamine
Definition
sympathomimetic - non selective
DA, then B1, then a1
cardiogenic shock, neurogenic shock, septic shock
low dose - gi and renal
medium - cardiac
high - inc BP
Term
dobutamine
Definition
B1 - agonist
increase cardiac contractility
cardiogenic shock
septic shock
CHF
Term
albuterol
Definition
b2 agonist
COPD asthma
Term
metaproterenol
Definition
b2 agonist
COPD asthma
Term
pirbuterol
Definition
b2 agonist
COPD asthma
Term
salmeterol
Definition
b2 agonist
COPD asthma
Term
terbutaline
Definition
b2 agonist
premature labor causing uterine relaxation
Term
phenylephrine
Definition
a1 agonist
raise BP but more reflex bradycardia
hemorrhoids, nasal congestion
Term
midodrine
Definition
a1 agonist
Term
cocaine
Definition
indirect sympathomimetic
inhibits NE reuptake
Term
sudafed
Definition
indirect sympathomimetic
stimulate NE release
Term
acebutolol
Definition
selective b blocker
partial agonist
membrane stable
Term
atenolol
Definition
selective b blocker
Term
esmolol
Definition
selective b blocker
acute treatment of arrythmia, preoperative hypertension, ischemia
Term
metoprolol
Definition
selective b blocker
Term
nadolol
Definition
nonselective b blocker
chronic hypertension
Term
pindolol
Definition
nonselective b blocker
partial agonist
Term
propranolol
Definition
nonselective b blocker
membrane stabilizing
Term
timolol
Definition
nonselective b blocker
glaucoma
Term
labetalol
Definition
b blocker and a blocker
moderate to severe hypertension, emergency treatment of hypertensive crisis
Term
phenoxybenzamine
Definition
non selective a blocker
noncompetative blocker
pre-surgery
inoperable pheochromocytoma
Term
phentolamine
Definition
non selective a blocker
short acting
used to dx pheochromocytoma
used during surgery
reverse NE effects
prevent local tissue necrosis
dentist
Term
prazosin
Definition
a1 blocker
mild to mod hypertension
BPH
raynauds
PTSD
"first dose phenomenon"
Term
terazosin
Definition
a1 blocker
BPH, hypten, long t1/2, not for PTSD
Term
doxazosin
Definition
a1 blocker
BPH, hypten, long t1/2, not for PTSD
Term
tamulosin
Definition
a1 blocker
subtype A
BPH with less systemic side effects
abnormal ejac
Term
alfuzosin
Definition
a1 blocker
BPH stored in the prostatic tissue
Term
silodosin
Definition
a1 blocker
subtype A
BPH with less systemic side effects
abnormal ejac
Term
reserpine
Definition
sympathetic neuronal blockers
dec uptake of DA and NE
reduce BP, dec CO,
Term
methyldopa
Definition
affects a2 and causes decrease in SNS nerve activity
renin release, dec HR, dec CO
treat hypertension during prenancy
causes autoimmune disorders
Term
clonidine
Definition
affects a2 and causes decrease in SNS nerve activity
comes in patch
primary hypertension
rebound hypertension
treat migrain, ADHD, PTSD, Alcohol withdrawl
Term
guanfacine
Definition
affects a2 and causes decrease in SNS nerve activity
causes less sedation and withdrawl syndromes
antihypertensive
Term
nicotine
Definition
ganglionic stimulants (mostly PNS effects)
stim at low dose
depress at high dose
Term
Mecamylamine
Definition
ganglionic blockers (most SNS effects)
blocks neuronal nicotinic receptors
severe or malignant hypertension
treat tourettes
crosses BBB
Term
l-dopa
Definition
dopaminergic agent
Term
l-dopa and cabidopa
Definition
dopaminergic agent
Term
dopa and carbidopa and entacapone
Definition
dopaminergic agent
Term
bromocryptine
Definition
dopaminergic agent
stim post-synaptic dopamine receptors
if cannot tolerate dopa
may dec on off
used to treat lactation
Term
pramipexole
Definition
dopaminergic agent
stim post-synaptic dopamine receptors
first line, may have antioxidant effects
Term
ropinirole
Definition
dopaminergic agent
stim post-synaptic dopamine receptors
first line, may have antioxidant effects
Term
amantadine
Definition
dopaminergic agent
stim release of dopamine
origonally antiviral
inhibit reuptake
less effective than dopa, more than antichol
Term
seligiline
Definition
MAO B inhib
used in later stage
may slow progression
Term
entacapone
Definition
COMT inhibit
Term
benzotropine
Definition
antimusc agnet
reduce cholingeric activity
Term
trihexyphenidyl
Definition
antimusc agent
reduce chol activity
Term
clozapine
Definition
antipsychotic for managing effects of l-dopa
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