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Digestive for An. Lecture Exam 2
digestive system
165
Anatomy
10/31/2010

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Term
main functions of digestive system (3)
Definition
processes food, extracts nutrients, eliminates waste
Term
GI =
Definition
gastrointestinal tract of alimentary canal
Term
Food does not "enter" the body until it is...
Definition
absorbed by cells.
Term
About how long is the GI tract?
Definition
About 9 meters long.
Term
lumen
Definition
space in the GI tract
Term
general function of mouth
Definition
bite, chew, swallow
Term
general function of pharynx and esophagus
Definition
Term
general function of stomach
Definition
mechanical digestion; absorption of water and alcohol
Term
general function of small intestine
Definition
chemical and mechanical digestion, and absorption
Term
general function of large intestine
Definition
absorb electrolytes and vitamins (B & K)
Term
general function of rectum and anus
Definition
defecation
Term
What are the layers of the GI tract (inside to out)?
Definition
1. Mucosa
2. Submucosa
3. Muscularis
4. Serosa
Term
What is the sentence for layers of the GI tract?
Definition
Michigan Sucks Michigan Sucks!
Mucky Submarines Must Sink
Term
What are the three layers in the mucosal layer?
Definition
Epithelium,
lamina propria,
muscularis mucosae.
Term
In the epithelium layer of the mucosal layer, what kinds of tissues are where?
Definition
Tough tissue (stratified squamous) in mouth, esophagus, and anus.
More fragile tissue (simple columnar) everywhere else.
Term
The epithelium layer of the mucosal layer secretes _____ and absorbs _______ .
Definition
The _______ layer of the mucosal layer secretes enzymes and absorbs nutrients.
Term
goblet cells
Definition
In the epithelium layer of the mucosal layer - secrete mucous onto cell surfaces.
Term
enteroendocrine cells
Definition
In the epithelium layer of the mucosal layer - secrete hormones controlling organ function.
Term
Lamina propria layer of the mucosal layer: def. and contains what?
Definition
thin layer of loose connective tissue; contains blood vessels and lymphatic tissue.
Term
Muscularis mucosae layer of the mucosal layer: def, functions
Definition
very thin layer of smooth muscle; causes folds to form in mucosal layer, and increases local movements which increases absorption by exposing "new" nutrients
Term
submucosa layer: def, contains what?
Definition
=loose connective tissue
-contains blood vessels, glands, and lymphatic tissue
Term
submucosal (Meissner's) plexus
Definition
part of the submucosal layer; involuntary nerves, innervation; does vasoconstriction, and local movement of muscularis mucosa
Term
Skeletal muscle in the muscularis layer: locations and function
Definition
In mouth, pharynx, upper esophagus, and anus.
Voluntary control over swallowing and defecation
Term
Smooth muscle in the muscularis layer: what kind of control, components of the smooth muscle layer, functions
Definition
Involuntary control
Inner circular fibers and outer longitudinal fibers
Mixes, crushes, and propels food along by peristalsis
Term
In the muscularis layer, the smooth muscle consists of inner ________ fibers and outer _________ fibers.
Definition
In the muscularis layer, the smooth muscle consists of ______ circular fibers and ________ longitudinal fibers.
Term
What plexus is on the outside of the muscularis layer?
Definition
Myenteric / Auerbach's plexus
Term
What is the function of the myenteric/Auerbach's plexus?
Definition
Innervation of circular and longitudinal smooth muscle layers (of muscularis layer).
Term
The myenteric/Auerbach's plexus of the ______ layer can be __________/_____________ based on ______.
Definition
The ___________ of the muscularis layer can be stimulated/inhibited based on stress levels.
Term
Serosa layer: def, location, function
Definition
Serous membrane
Covers all organs and wall cavities not open to the outside of the body.
Secretes serous fluid (slippery fluid).
Term
Serous fluid
Definition
Slippery fluid secreted by the serosa layer.
Term
Peritoneum =
Definition
continuous layer of tissue that covers the abdominal cavity.
Term
2 parts of the peritoneum
Definition
1. Parietal : covers wall of abdominal cavity
2. Visceral : covers organs (same as serosa layer)
Term
mesenteries: =, functions (3)
Definition
double layers of peritoneum; hold organs in place, prevent friction due to serous fluid, fat deposits cushion organs.
Term
Name the 4 mesenteries.
Definition
Lesser omentum
Greater omentum
Mesentery proper
Mesocolon
Term
Where is the lesser omentum?
Definition
Between stomach and liver.
Term
Where is the greater omentum?
Definition
Stretches down from stomach over small intestine.
Term
What is the function of the mesentery proper?
Definition
Holds coils of small intestine in place.
Term
What is the function of the mesocolon?
Definition
Holds colon to back of cavity wall.
Term
Peritonitis; =, caused by?
Definition
acute inflammation of peritoneum; caused by contamination from infectious microbes during surgery or from rupture of abdominal organs
Term
Primary Peritoneal Carcinoma
Definition
rare cancer where tumors from in peritoneum
Term
Primary Peritoneal Carcinoma almost exclusively affects....
Definition
...women.
Term
Primary Peritoneal Carcinoma has a ____ survival rate; patients are usually given _____ after diagnosis.
Definition
poor; 12-25 months
Term
General functions of the mouth (4):
Definition
food intake, mechanical digestion (mastication), chemical digestion, deglutition (swallowing).
Term
Mastication
Definition
mechanical digestion
Term
deglutition
Definition
swallowing
Term
General structures of the mouth:
Definition
Cheeks, lips, tongue, palate, teeth, and associated muscles.
Term
oral orifice
Definition
opening to mouth
Term
oral cavity proper
Definition
area where tongue sits
Term
vestibule
Definition
area between teeth and lips
Term
fauces
Definition
opening to pharynx
Term
labial frenulum
Definition
skin that holds lips to gums
Term
hard palate
Definition
bony part of roof of mouth
Term
soft palate
Definition
tissue part of roof, leading to uvula
Term
What are the two types of cells in salivary glands?
Definition
Serous - secrete a watery fluid
Mucous (pale-staining, in slide) - secrete slimy mucous
Term
Acini
Definition
sac-like clusters of salivary cells that empty into a duct
Term
Functions of saliva (5):
Definition
-wets food - easier swallowing
-dissolves food - tasting
-bicarbonate ions buffer acidic foods
-salivary amylase begins chem. digestion of starch
-protects mouth from infection w/ rinsing action
Term
How much saliva does the body produce per day?
Definition
1 - 1.5 liters.
Term
What enzyme in saliva helps destroy bacteria?
Definition
Lysozyme.
Term
What enzyme in saliva begins the chemical digestion of starch?
Definition
Salivary amylase.
Term
Mump =
Definition
myxovirus that attacks the parotid gland
Term
Symptoms of mumps (3):
Definition
-inflammation and enlargement of parotid gland
-fever, malaise, sore throat (esp. swallowing sour)
-swelling on one or both sides
Term
When did the vaccine for mumps become available?
Definition
1967
Term
tongue =
Definition
muscular organ that aids with food manipulation
Term
Where do tongue muscles connect to?
Definition
hard palate, mandible, hyoid bone, and styloid process.
Term
lingual frenulum
Definition
skin that connects tongue to floor of mouth
Term
papillae
Definition
bumps on tongue; taste buds located on sides of tongue on papillae
Term
Pharynx =
Definition
funnel-shaped opening from nasal cavities to larynx/esophagus
Term
What are the 3 parts of the pharynx?
Definition
Nasopharynx, Oropharynx, Laryngopharynx
Term
Food travels from the oral cavity to...
Definition
oropharynx, laryngopharynx, down the esophagus.
Term
What does the epiglottis do?
Definition
The epiglottis prevents food from entering the trachea.
Term
peristalsis
Definition
wavelike muscular contractions
Term
Steps to deglutition:
Definition
-Tongue collects food/bolus and forces into fauces
-Food enters pharynx
-Blockage happens; esophagus is the only way.
-Food is forced down esophagus via peristalsis.
Term
What kind of blockage happens during deglutition?
Definition
-Tongue blocks oral cavity
-Soft palate blocks nasopharynx
-Larynx lifts up and epiglottis blocks trachea
Term
How long is the esophagus?
Definition
25-30 cm long
Term
Between what two structures does the esophagus run?
Definition
In front of spine, behind trachea.
Term
hiatus
Definition
Where the esophagus pierces the diaphragm
(hiatus = opening)
Term
cardiac orifice
Definition
Where the esophagus enters the stomach.
Term
Mucosa layer in the esophagus
Definition
very smooth layer of epithelial cells
Term
Submucosa layer in esophagus:
Definition
large mucous glands
Term
Muscularis layer in esophagus:
Definition
upper 1/3 - skeletal muscle
middle - mixed
lower 1/3 - smooth muscle
Term
lower esophageal sphincter
Definition
at the end of the esophagus
Term
True/false: The esophagus has a serosal layer along its entire length.
Definition
False: There is not a serosal layer above the diaphragm; there is a serosal layer below the diaphragm.
Term
Above the diaphragm, what takes the place of the serosal layer on the esophagus?
Definition
adventitia tissue
Term
adventitia tissue
Definition
fibrous connective tissue that replaces the serosal layer on the esophagus above the diaphragm.
Term
distention of esophagus; feels like and caused by?
Definition
ballooning/enlargement of esophagus feels like chest pain or heart attack; is caused by the lower esophageal sphincter not opening.
Term
If lower esophageal sphincter fails to close...
Definition
GERD - stomach acids enter esophagus and cause heartburn (gastrointestinal reflux disorder)
Term
GERD
Definition
gastrointestinal reflux disorder
Term
Eating a large meal and laying down in front of the tv is not good for...
Definition
...a weak esophageal sphincter.
Term
Smoking and alcohol make gastroesophageal situations _______ because they cause the _________ to ___________.
Definition
_________ and __________ make gastroesophageal situations worse because they cause the esophageal sphincter to relax.
Term
Stomach: looks like, where?
Definition
j-shaped organ in upper left abdominal cavity
Term
4 regions of stomach:
Definition
1. cardiac - top, near sphincter
2. fundus - top
3. body - middle
4. pyloric - bottom
Term
cardiac sphincter
Definition
top of stomach
Term
pyloric sphincter
Definition
bottom of sphincter
Term
Greater curvature
Definition
bottom, bigger curve of stomach
Term
Lesser curvature
Definition
top, smaller curve of stomach
Term
rugae
Definition
thick folds of tissue that look like wrinkles
Term
What layers of the stomach form rugae?
Definition
mucosa and submucosa
Term
function of rugae
Definition
allow stomach to expand
Term
A full stomach has a ...
Definition
...smooth inner surface.
Term
gastric pits
Definition
small holes in mucosa layer of stomach
Term
The base of a gastric pit splits into ...
Definition
2 or 3 gastric glands
Term
Gastric pits/glands: function
Definition
secrete substances important for digestion.
Term
Gastric pits are folded into...
Definition
the rugae of the stomach
Term
4 types of gastric gland cells:
Definition
1.mucous neck cells - secrete mucous
2.parietal cells - secrete hydrochloric acid + intrinsic factor
3.chief cells: secrete pipsinogen
4.enteroendocrine: secrete hormones and paracrine messengers
Term
Functions of gastric secretions: mucous neck cells
Definition
SECRETE MUCOUS: lubricates lumen for food passage
Term
Functions of gastric secretions: parietal cells
Definition
SECRETE HYDROCHLORIC ACID AND INTRINSIC FACTOR: HCl activates pepsinogen, breaks up connective tissue + plant cell walls, protects body by killing bacteria; intrinsic factor absorbs B12
Term
Functions of gastric secretions: chief cells
Definition
SECRETE PEPSINOGEN: active form, pepsin, breaks down proteins
Term
Functions of gastric secretions: Enteroendocrine cells
Definition
SECRETE HORMONES + PARACRINE MESSENGERS: Ex, paracrine is a histamine --- stimulates HCl secretion
Term
Is the submucosal layer of the stomach similar to the submucosal layer of the esophagus?
Definition
Yes; also, it is folded into the rugae of the stomach.
Term
What are the 3 layers in the muscularis layer of the stomach?
Definition
1. outer longitudinal
2. middle circular
3. inner oblique
Term
What is the function 3 layers of muscle in the muscularis layer of the stomach?
Definition
Greater mixing of stomach contents.
Term
Pacemaker cells in the _______ layer of the muscularis layer of the stomach helps produce __________ muscle contractions.
Definition
outer longitudinal; peristaltic
Term
Where does the serosal layer of the stomach begin?
Definition
Inferior to the diaphragm.
Term
What is another name for the serosal layer of the stomach?
Definition
visceral peritoneal layer.
Term
Length of small intestine
Definition
20 ft long
Term
Width of small intestine
Definition
1 inch wide
Term
3 parts of small intestine, w/ lengths:
Definition
1. duodenum - 10 inches
2. jejunum - 8 ft
3. ilium - 12 ft
Term
Where does the small intestine end?
Definition
Iliocecal valve.
Term
folds in small intestine =
Definition
plicae circulares
Term
What is the difference between stomach rugae and small intestine plicae circulares?
Definition
Plicare circulares cannot expand like rugae.
Term
Plicae circulae have ______ and _______ layers.
Definition
Plicae circulae have mucosal and submucosal layers.
Term
Plicae circulae are covered in ________ , which make up the ________ layer of plicae circulae.
Definition
villi; musocal.
Term
Villi cells have ________ from the _________.
Definition
brush borders; microvilli.
Term
intestinal crypts
Definition
in mucosa layer of stomach; similar to gastric glands
Term
What kind of cells are in intestinal crypts?
Definition
goblet cells (mucous-producing cells), absorptive cells, stem cells, and cells that protect from infection.
Term
What are nutrients absorbed by?
Definition
Nutrients are absorbed by the cells of villi.
Term
How do nutrients enter the blood stream?
Definition
through a vein
Term
How do absorbed nutrients go to the liver?
Definition
Through the hepatic portal system.
Term
The __________________ is a "stop" before blood goes back to the __________.
Definition
The hepatic portal system is a _______ before blood goes back to the heart.
Term
General function of liver:
Definition
helps remove absorbed nutrients
Term
Where do absorbed nutrients go?
Definition
-Nutrients absorbed by cells of villi and enter blood stream via vein.
-Nutrients go to liver via the hepatic portal system; liver helps remove absorbed nutrients.
Term
How long is the pancreas?
Definition
5 inches long
Term
How thick is the pancreas?
Definition
1 inch thick
Term
Where is the head of the pancreas close to?
Definition
The head of the pancreas is close to the the curve in the j-shaped duodenum.
Term
hepatopancreatic ampull
Definition
bile and pancreatic duct that empties into the duodenum
Term
Where does the pancreas open?
Definition
into duodenum, 4 inches below the pyloric sphincter
Term
Islets of Langerhans
Definition
tissue in pancreas; produce hormones; 1% of a pancreatic gland; pale-staining in slide
Term
Acini
Definition
tissue in pancreas; 99% of gland, pale-staining in slide; produce pancreatic juice.
Term
What are the three main components of pancreatic juice?
Definition
a) water
b) enzymes - help with digestion
c) sodium bicarbonate - neurtralize stomach acids
Term
What are the enzymes in pancreatic juice?
Definition
pancreatic amylase - digests starch
pancreatic lipase - digests fat
proteases - digests proteins
ribonucleases - nueutralizes stomach acids
Term
What does pancreatic amylase do, and where does it come from?
Definition
digests starch; in pancreatic juice
Term
Where does pancreatic lipase, and where does it come from?
Definition
digests fat; in pancreatic juice
Term
What do proteases do, and where do they come from?
Definition
digests proteins; in pancreatic juice
Term
What do sodium bicarbonates do, and where do they come from?
Definition
neutralizes stomach acids; in pancreatic juice.
Term
hepatocyte
Definition
liver cell
Term
Hepatocytes are arranged in...
Definition
lobules.
Term
Lobules are _____ in shape.
Definition
hexagonal
Term
A lobule has a ______ _______ surrounded by ______ and __________.
Definition
central vein; cords; sinusoids
Term
cords
Definition
arrangements of hepatocytes (lobule)
Term
sinusoids
Definition
gaps filled with blood (lobule)
Term
Lobules are bordered by _________ ___________.
Definition
hepatic triads.
Term
hepatic triad
Definition
hepatic vein, artery, bile ductile
Term
function of lobules/liver =
Definition
absorb nutrients from GI tract and cleanse blood.
Term
Blood is collected from the the GI tract through the...
Definition
..hepatice portal vein.
Term
When blood is first collected from the GI tract, is it ________ rich and _________poor.
Definition
nutrient rich/ oxygen poor
Term
Blood flow through lobule
Definition
- Blood collected from GI tract through HPV
-travels to hepatic veins of triads and through lobule
-leaves lobule through central vein to heart
-Arterial blood from hepatic artery also flows through lobules, supplying oxygen to liver.
Term
How does blood travel out of a lobule to the heart?
Definition
central vein to heart;
Term
What creates bile, and how does it get to the gallbladder?
Definition
lobules/hepatocytes create bile and it blows to gallbladder via ductiles.
Term
Function of bile:
Definition
helps w/ digestion and removal of wastes from the liver.
Term
Components of bile: which aid in digestion, and which aid in waste?
Definition
bile salts - digestion
lechithin - digestion
cholestrol - waste
bile pigments - waste
Term
Bile salts: = and function
Definition
= bile acids conjugated w/ potassium or sodium
-fat emulsification
Term
What is lechithin and what does it do?
Definition
A component of bile; aids in digestion
Term
What is the function of cholestrol?
Definition
Cholestrol, a component of bile, is produced in and removed by the liver as waste.
Term
What does hemoglobin break down into, and what are the parts' functions?
Definition
heme = broken down into iron and bilirubin
globin = a reuseable protein
Term
bilirubin
Definition
a pigment of bile
gives bile, urine, and feces color