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Diabetes Alpha - Glucosidase
Diabetes Alpha - Glucosidase
11
Pharmacology
Professional
09/13/2012

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Cards

Term
How do α-glucosidase inhibitors work?
Definition

Inhibits alpha-glucosidase in the intestine and alpha - amylase in the panreas resulting in delayed absorption of glucose. Inhibits metabolism of sucrose to glucose and fructose

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Term
Brand name for acarbose?
Definition
Precose
Term
Brand name for Miglitol
Definition
Glyset
Term
Do alpha-glucosidase inhibitors decrease pre or post prandial blood glucose?
Definition
postprandial
Term
When are alpha - glucosidases inhibitors taken?
Definition

both acarbose and miglitol are started at 25 mg with the first bite of each main meal

Term
Side effects of alpha - glucosidase inhibitors?
Definition

Gi effects (flatulence, diarrhea)

Increases HDL and decreases TG

Weight neutral

Term
When are alpha - glucosidase inhibitors contraindicated?
Definition

Irritable bowel syndrome (IBS); intestinal obstruction - do not use with any significant GI disease

Term
[image]
Definition
Statement. Not a question.
Term
Should an alpha glucosidase inhibitor be taken when a meal is skipped?
Definition
No. skip a meal, skip a dose
Term
Do alpha glucosidase inhibitors cause hypoglycemia?
Definition

NO. These agents, by themselves, do not cause low blood sugar.

Term
What should one do if they experience low blood sugar while on an alpha glucosidase inhibitor?
Definition

low blood sugar after taking acrabose or miglitol CANNOT be treated with sucrose (present in fruit juice) or with table sugar or candy. Must treat hypoglycemia with a glucose tablet or gel. 

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