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Dermatology
Acne/Autoimmune
70
Medical
Graduate
12/02/2009

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Cards

Term
A chronic disease of apocrine sweat glands found in the axilla, groin, under breasts, etc. that heal w/ scarring?
Definition
Hidradenitis Suppurativa
Term
When does hidradenitis suppurativa occur?
Definition
Only after puberty
Term
What can Hidradenitis Suppurativa form?
Definition
Sinus tracts
Term
Name 6 risk factors of Hidradenitis Suppurativa.
Definition
1) Women 2) AA 3) h/o acne 4) Tight, curly hair (ingrown) 5) Obesity 6) Tight clothing
Term
Name 5 tx for Hidradenitis Suppurativa.
Definition
1) I&D 2) PO or topical abx 3) Bleach baths 4) Laser 5) Accutane
Term
A chronic, autoimmune blistering dz that causes subepidermal blisters.
Definition
Bullous Pemphigoid
Term
Describe the pathophysiology of bullous pemphigoid.
Definition
IgG autoantibodies bind to the basement membrane leading to separation of dermis from epidermis
Term
What is the cause of bullous pemphigoid?
Definition
Unknown
Term
How common is bullous pemphigoid? Who does it more commonly occur in?
Definition
Rare. Onset usu. >65yo, men = women
Term
Describe the lesions caused by bullous pemphigoid.
Definition
Tense bullae that heal /s scarring
Term
Where is the most common location of bullous pemphigoid?
Definition
Fleural surfaces
Term
Name 5 tx for bullous pemohighoid.
Definition
1) Topical steroids 2) Long-term oral prednisone 3) Tertacycline 4) Methotextrate 5) Immunosuppressants
Term
Condition that causes areas of complete depigmentation because melanocytes are destroyed.
Definition
Vitiligo
Term
What is the avg. age of onset of vitiligo?
Definition
20yo
Term
Describe the visual appearance of areas affected by vitiligo. What are the most common locations on the body?
Definition
Sharply circumscribed white patches that become confluent. MC face, neck, scalp.
Term
What is the cause of vitiligo?
Definition
Unknown. Autoimmune, some genetic inheritance.
Term
Name 7 tx for vitiligo.
Definition
1) Topical steroids 2) Topical immunomodulators (protopic, Elidel) 3) UV 4) Laser 5) Oral steroids 6) Depigmentation 7) Surgery
Term
An autoimmune blostering d/o associated w/ Celiac's dz.
Definition
Dermatitis herpetiformis
Term
Most common age of dermatitis herpetiformis?
Definition
30's
Term
Describe the rash of dermatitis herpetiformis.
Definition
Very pruritic, burning sensation, erythematous excoriated papules or plaques and herpetiform lesions
Term
What is the most common location on the body affected by dermatitis herpetiformis?
Definition
Elbows, knees, and buttock. Palms and soles are spared.
Term
How is dermatitis herpetiformis dx?
Definition
Biopsy
Term
What is the tx for dermatitis herpitiformis?
Definition
1) Gluten free diet 2) Dapsone
Term
What are side effects of dapsone? (4)
Definition
Hemolysis, methemoglobinemia, peripheral neuropathy, cross rxn w/ sulfa allergy
Term
What are complications of dermatitis herpetiformis?
Definition
lymphoma and intestinal CA
Term
Skin condition described as having salmon colored plaques with a thick, silvery scale?
Definition
Psoriasis
Term
What is the etiology of psoriasis? What causes the sx?
Definition
Autoimmune. Fast turnover of dermal cells - 3 to 5 days (normal 23days)
Term
What is the most common location of psoriasis? What is the most common type?
Definition
Elbows and knees. Plaque psoriasis.
Term
Name the 5 types of psoriasis.
Definition
1) Plaque 2) Guttate 3) Inverse 4) Pustular 5) Erythrodermic
Term
Describe appearance of guttate psoriasis.
Definition
<1cm "dew drop" plaques all over the body.
Term
Who is guttate psoriasis most common in?
Definition
Young, healthy people. Typicalll /p strep infection.
Term
Describe appearance of inverse psoriasis. Where does it typically occur?
Definition
Moist, "beefy red", not scaly. Occurs in skin folds, axillae, groin.
Term
Where does pustular psoriasis typically occur?
Definition
palms and soles
Term
Describe appearance of erythrodermic psoriasis.
Definition
Generalized erythema and scale.
Term
Is psoriasis contagious?
Definition
No
Term
What is the name for psoriasis being triggered after trauma, such as surgery or tattoo?
Definition
Koebner phenomenon
Term
What meds can trigger psoriasis?
Definition
NSAIDS, Lithium, Inderal, Indomethacin, anti-malarials, beta blockers
Term
What complication of psoriasis occurs in 10-30% of sufferers?
Definition
psoriatic arthritis
Term
What are anti-inflammatory tx for psoriasis?
Definition
Topical and intranasal steroids
Term
Name 4 immunosuppresant tx for psoriasis.
Definition
1) UV 2) Biologics (Enbrel, Humira, Amevive, Remicade, Raptiva) 3) Methotextrate 4) Cyclosporin
Term
What tx for psoriasis helps decrease scale?
Definition
Vitamin D analogue (Dovonex, Vectical)
Term
A skin conditions whose hallmark prodome is a herald patch, a salmon colored 1-2cm round patch.
Definition
Pityriasis Rosea
Term
Who does pityriasis rosea typically affect? Where is the most common location?
Definition
15-40yo. Trunk.
Term
Describe the secondary eruption of pityriasis rosea.
Definition
Collarette of fine scale OR Christmas tree pattern that is symmetric and gen. on trunks and extremities
Term
What is the cause of pityriasis rosea? When does it most commonly occur?
Definition
Viral. Spring and Fall.
Term
What is the tx for pityriasis rosea?
Definition
None - self limiting 8-12wks. UV can help, mild topical steroids PRN.
Term
What other two conditions that are typically seen together w/ eczema as part of the classic triad?
Definition
Asthma and allergies
Term
With eczema, which typically comes first, the rash or the itch?
Definition
The itch that rashes
Term
Describe the physical appearance of skin affected by eczema.
Definition
Red papules or plaques with scale, lichenification
Term
What part of the body does eczema typically affect in children?
Definition
Flexural surfaces
Term
Describe the appearance of nummular eczema.
Definition
Annular, coin-shaped lesions
Term
What are potential triggers of eczema?
Definition
1) Harsh chemicals/soaps 2) Excessive nathing/dry skin 3) Foods that worsen 4) Pet dander 5) Excessive heat
Term
Name 4 meds to tx eczema.
Definition
1)Topical steroids 2) Topical immunosuppressants (Elidel and Protopic) 3) UV light 4) Antihistamines
Term
How common is acne vulgaris? Who is it moct common in?
Definition
Affects >90% of the population, MC in adolescents
Term
What are the 2 mian types of acne lesions?
Definition
Non-inflammatory and inflammatory
Term
What are the 2 types of non-inflammatory acne lesions?
Definition
Comedones - blackheads (open) and whiteheads (closed)
Term
What are the 2 types of inflammatory acne lesions?
Definition
Papules/pustules (superficial) and cysts/nodules (deep)
Term
Name 4 causes of acne vulgaris.
Definition
1) Skin cells plug hair follicle 2) Excess sebum 3) Bacteria (P. Acnes) 4) Inflammation
Term
What can be used to tx P. Acnes? What is a difficulty with tx it?
Definition
Topical abx (clindamycin, erythromycin), high resistance - need to use benzoyl peroxide to prevent resistance
Term
What acne med. is very teratogenic and prescription requires signing the Ipledge system?
Definition
Oral isotretinoin (accutane, sotret, claravis, amnesteem)
Term
What complication of acne can lead to hospitalization? What causes it?
Definition
Acne Fulminans. High levels of testosterone and P. acnes
Term
Rosacea is a common skin condition that involves __________ and ___________.
Definition
Erythema, rosacea
Term
Name the 4 types of rosacea.
Definition
1) Vascular 2) Acne 3) Phymatous 4) Occular
Term
What is the most common type of rosacea? Describe its presentation.
Definition
Vascular, facial redness that spares the periorbital area
Term
Describe acne rosacea.
Definition
Papules and pustules w/ central facial redness and telangiectasias
Term
Describe the presentation in phymatous rosacea.
Definition
Skin thickening and irregular surface
Term
Where does phymatous rosacea affect?
Definition
MC the nose (rhinophyma), also chin, forehead, eyelids
Term
What is the tx for phymatous rosacea?
Definition
Only tx is surgery
Term
Describe ocular rosacea.
Definition
Usu. chronic blepharitis and conjunctivitis, dryness, sting/burning of eyes
Term
What triggers rosacea?
Definition
Sun, alcohol, heat, exercise, spicy foods, alcohol
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