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Chapter 9: Cerebral Spinal Fluid
N/A
7
Physiology
Undergraduate 2
10/16/2013

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Term
Cerebrospinal fluid (CSF)
Definition
A clear, watery fluid that bathes the CNS
Cushions the brain
Maintains a stable interstitial fluid environment
An unltrafiltrate of plasma
Term
What produces CSF?
Definition
CSF is secreted by ependymal cells of the choroid plexus
Term
What is the total volume of CSF in a human body?
Definition
125-150mL
Term
How much CSF is produced daily?
Definition
400-500mL and it is recycled three times per day
Term
Normal CSF Values consist of
Definition
Clear
Less than 5 WBC
Diff=60-70% lymphocytes
No RBC
Less than 60 mg/dL of protein
Greater than 60mg/dL of glucose
Spec Grav= 1.006-1.009
Sterile
Term
Clinical symptoms of bacterial meningitis are
Definition
Decrease in glucose. Less than 40mg/dL

Increase in protein. Greater than 250mg/dL

WBC increased 10-1,000 WBC

Diff= Mostly neutrophils

Culture= Positive
Term
Viral Meningitis
Definition
Culture = Negative

Glucose is normal

Protein is moderate. Less than 100mg/dL

WBC is less than 100/uL

Differential= Lymphocytes
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